Effect of sex and acute dosing of (2<i>R</i>,6<i>R</i>)-HNK on withdrawal latency in the hot plate assay. by Todd M. Hillhouse (1359186)

“…<p>(A) There was a temperature-dependent decrease in withdrawal latency for male and female mice. …”

Changes in osteoblast differentiation and function of 4 week-old <i>Lmna</i>^−/− mice. by Wei Li (7081)

“…(<b>C</b>) Sections of plastic embedded proximal tibiae (secondary spongiosa) from <i>Lmna</i>^−/− mice and WT controls (n = 10 per group) were stained sequentially with toluidine blue (upper panels, Magnification ×40) for osteoblasts (black arrows) and osteocytes (red arrows) and ALP (lower panels, Magnification ×20) for osteoblasts (arrows). (<b>D</b>) A significant decrease (−47%) in the number of ALP expressing osteoblasts (N.Ob) and a significant decrease in osteocyte number (N.Ot) (−50%) were seen in <i>Lmna</i>^−/− mice compared with WT^+/+ mice. …”

XAV939 inhibits TNKS PARP-activity in MB cell lines. by Cristiano Renna (585758)

Effect of cell density on cell survival after high-dose irradiation. by Marlon R. Veldwijk (512440)

“…A significant decrease (P<0.0001) in surviving fraction (SF) after 12 Gy was found when seeding 50,000 cells/T25 flask (open symbol) compared with 10,000 cells/T25 flask. …”

Effect of MEHP and PMA on the gene transcription of TSPO, PKCε, PPAR-α, PPAr-β/δ, and PPAR-γ. by Enrico Campioli (336888)

“…Cells were seeded for 24 h before treatment with MEHP (A–C) or PMA (D) and collected after the indicated time points (A) or after 4 days (B–D). qRT-PCR results are normalized to RPS18, expressed in terms of mean and S.E.M. calculated from 3 independent experiments, and presented as fold increase or decrease compared to control. …”

Short-term thalidomide has little effects on AD-like pathology and BACE1 regulation. by Ping He (33281)

Sensitivity of simulated pathogen diversity to host lifespan and environmental transmission. by Benjamin Roche (84064)

“…The <i>z</i>-axis corresponds to the mean antigenic diversity over the 40-y period. A decrease in environmental uptake rate (<i>x</i>-axis) dramatically reduces mean antigenic diversity (average of the number of strains) and switches the phylogenetic pattern from one that depicts broad coexistence to an immune escape profile. …”

Proliferation and apoptosis evaluation. by Dong Sun (165703)

“…(<b>K</b>) hAFSC group at 14 days after hAFSCs injection: The apoptotic cells were significantly decreased in animals in the hAFSC group (bar, 50 µm). …”

Effect of OWB extract and CA on PGE2 release and COX-2 expression in LPS-induced murine peritoneal macrophages. by Durbadal Ojha (475076)

“…The RT–PCR data are expressed as Means ± SD from triplicate experiments. Asterisks indicate a statistically significant decrease (**P, 0.05) in COX-2 expression, compared with infected macrophages.…”

Effect of freezing with oscillating magnetic fields on the physical and sensorial characteristics of mango (Mangifera indica L. cv. ‘Kent’) by Enzo Aldoradin Puza (6935378)

“…Freezing using OMF with a Cells Alive System (CAS) freezer caused negative changes to the thawed mango, mainly a decrease in firmness, with results similar to those reported elsewhere using conventional freezing.…”

The E1B19K protein plays an essential role in adenovirus-mediated autophagy. by Sujan Piya (336435)

“…Deletion of E1BK jeopardizes adenovirus-associated autophagy, as assessed by a significant decrease in the LC3 membrane localization. …”

MβCD treatment is effective in sequestering cholesterol from the plasma membrane. by Bárbara Hissa (176168)

Impairment of cognitive memory functions in Auts2 mutant mice. by Kei Hori (840871)

Balance of NMDA and GABA receptor activation and two ways of eliciting bursts or pauses of the DA neuron. by Ekaterina O. Morozova (3386927)

“…The insert illustrates a smooth frequency decrease during application of GABAR conductance (<i>g</i>_<i>NMDA</i> = 0 mS/cm²). …”

Bcl-xL siRNA effectively knocks down Bcl-xL mRNA and protein and induces platelet apoptosis. by Shifang Yu (721211)

“…<p>Leukocyte-depleted apheresis platelets (LDPs) were transfected with siBcl-xL or negative control siRNA (siNC) at a final concentration of 50 nM. LDPs without transfection were used as blank controls (control). …”

Parasympathetic blockade by methylatropine prevents bradycardia during seizure and in the immediate post-ictal period. by William P. Schilling (7522238)

“…<b>D:</b> The change in heart rate for individual mice in the absence of methylatropine is shown. Note the rapid decrease in heart rate in the clonic period with a further decrease by the end of the tonic period. …”

<i>In vitro</i> and <i>in vivo</i> properties of aminotriazines used in this study. by David J. Matson (625974)

“…Analgesic efficacy was determined by a statistically significant (p < 0.05) decrease in formalin-induced flinching for which the same dose did not produce a reduction in movement in the open field assay that obviated the formalin result. …”

Cdk2 and PTPLAD1 interact with IR complex organization. by Martial Boutchueng-Djidjou (5832626)

“…The autoradiograms depict data from a typical experiment. Statistical values for salient time points are mean ± s.d. of % of initial densitometric values (two-tailed unpaired Student’s t-test). …”

Ellagic Acid Derivatives from <em>Terminalia chebula</em> Retz. Downregulate the Expression of Quorum Sensing Genes to Attenuate <em>Pseudomonas aeruginosa</em> PAO1 Virulence by Sajal Sarabhai (104656)

“…<em>C. elegans</em> fed on F7-treated <em>P. aeruginosa</em> showed enhanced survival with LT50 increasing from 24 to 72 h. LC-ESI-MS of F7 revealed the presence of ellagic acid derivatives responsible for anti QS activity in <em>T. chebula</em> extract.…”

Low dissolved oxygen levels increase stress in piava (Megaleporinus obtusidens): iono-regulatory, metabolic and oxidative responses by CARLOS E. COPATTI (7291634)

“…Fish were exposed to different DO levels, including 1.0, 2.0, 3.0, 4.0 and 5.0 mg L-1 of DO for 96 h, after which blood and tissue samples (liver, kidney, gill and muscle) were collected. …”