Beyond the polymerase-γ theory: Production of ROS as a mode of NRTI-induced mitochondrial toxicity - Fig 2 by Reuben L. Smith (4568143)

“…<p><b>A: mtDNA copy number was altered upon short term (1h) exposure to NRTIs</b> and <b>B: paraquat</b>. …”

Table_2_SNP-Based Genotyping Provides Insight Into the West Asian Origin of Russian Local Goats.XLSX by Tatiana E. Deniskova (5527175)

“…In addition, we addressed genetic relationships between local and global goat populations obtained from the AdaptMap project. Russian goats showed a high level of genetic diversity. Although a decrease in historical effective population sizes was revealed, the recent effective population sizes estimated for three generations ago were larger than 100 in all studied populations. …”

Heterodimerization of MC1R and MC1R-TUBB3 chimeric isoforms. by Cecilia Herraiz (836697)

Quantifying bactericidal effects of cold Ar-CAPP against diverse <i>E. coli</i> strains. by Elanie F. Briggs (22103678)

TS3 System parameters for different cases at which one harmonic source is turned off and the other two are present. by Abdallah Aldosary (21370131)

TS3 System parameters sensitivity analysis where HBF inductors values are changed by ± 2% and capacitors values by ± 5%. by Abdallah Aldosary (21370131)

Off-target analysis of CRISPR-Cas9 genome editing. by Zhen Zhou (184390)

Data_Sheet_1_Combined Use of Serum Uromodulin and eGFR to Estimate Mortality Risk.PDF by Babak Yazdani (305373)

“…Participants were categorized into four groups according to the median values of sUmod (LURIC: 146 ng/ml, VIVIT: 156) and eGFR (LURIC: 84 ml/min/1.73 m², VIVIT: 87). …”

Brain disintegration in <i>aP2- Drp1</i>^f/f neonatal mice. by Yuta Ibayashi (20404811)

Schematic overview of the down-stream genes regulated by eIF3a and the resultant functional effects. (A) by Darius J. R. Lane (381080)

“…Second, when eIF3a expression is abrogated, such as occurs in hypoxic tissues that are typical of advanced tumors <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057273#pone.0057273-Chen2" target="_blank">[77]</a>, <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057273#pone.0057273-Dellas1" target="_blank">[78]</a>, there is: <b>(i)</b> down-regulation of NDRG1, leading to a loss of differentiation and increased metastasis/invasion (shown herein); <b>(ii)</b> up-regulation of p27^kip1, resulting in the inactivation of the cell cycle and inhibited proliferation <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057273#pone.0057273-Dong2" target="_blank">[7]</a>; and <b>(iii)</b> decreased expression of RRM2 <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0057273#pone.0057273-Dong1" target="_blank">[6]</a>, preventing DNA synthesis and growth.…”

Assessment of myograph and smooth muscle cell contractile protein expression in ascending aortic tissues. by Zhen Zhou (184390)

Experimental timeline: by Christopher Rowan (21499924)

(Short-term) viral dynamics. by Sulav Duwal (152805)

B+S_pFV increases <i>f</i>, decreases V_T, and induces post-inspiratory activity in abdominal muscles and pre- and post-inspiratory activity in gengioglossus mu... by Robert T. R. Huckstepp (3391586)

Mature B cell depletion in ApoE^−/− mice treated with anti-BAFFR antibody. by Tin Kyaw (335986)

“…(B) CD93⁻ CD19⁺ mature B2 cells identified by FACS analysis significantly decreased in spleen, with CD93⁺ CD19⁺ immature B2 cells unaffected in anti-BAFFR-antibody treated mice. …”

Effect of E protein on the recognition of prM protein by human anti-prM mAbs. by Wen-Yang Tsai (108058)

“…(B) Dot blot binding assay using these 4 mAbs to recognize prM protein in the presence (expressed by prME) or absence (expressed by prM) of E protein in 1% NP40 lysis buffer (NP40). Decreasing amount of prM protein (expressed by prME) in 1% NP40 lysis buffer (column B, rows 3 to 7) and mixtures containing decreasing amount of prM protein in 1% NP40 lysis buffer and increasing amount of denatured prM protein in reducing (R) buffer (column A) were included to control for exposure and sensitivity of the assay signal, respectively. …”

Celastrol targets AR-ERG-p536 in T/E fusion expressing PCa cells at protein level. by Longjiang Shao (385841)

Light-Powered Self-Sustained Oscillators of Graphene Oxide/Liquid Crystalline Network Composites Showing Amplitude and Frequency Superposition by Jianchuang Wang (2898131)

“…When the composite film is embedded in a self-shadowing system, it produces an unconventional hybrid oscillation mode upon near-infrared light irradiation, i.e., bending and twisting oscillation coupled. Furthermore, when the aspect ratio of the film decreases, the twisting mode is suppressed and the actuator changes from a coupled mode to a single bending mode. …”

Key Roles of Bulk Viscosity and Acidity on Liquid–Liquid Phase Separation of Atmospheric Organic–Inorganic Mixed Aerosols by Yuanyuan Ye (4028186)

“…In this study, we introduced three representative WSOCs, i.e., sucrose (SUC), glycerol (GLY), and citric acid (CA), to increase the bulk viscosity of a model LLPS system composed of 1,2,6-hexanetriol (HXT) and ammonium sulfate (AS). …”

Light-Powered Self-Sustained Oscillators of Graphene Oxide/Liquid Crystalline Network Composites Showing Amplitude and Frequency Superposition by Jianchuang Wang (2898131)

“…When the composite film is embedded in a self-shadowing system, it produces an unconventional hybrid oscillation mode upon near-infrared light irradiation, i.e., bending and twisting oscillation coupled. Furthermore, when the aspect ratio of the film decreases, the twisting mode is suppressed and the actuator changes from a coupled mode to a single bending mode. …”