Development of a retinal pigment epithelium (RPE) tear after massive subretinal hemorrhage (SRH) in Patient 3, a 76-year-old woman with retinal angiomatous proliferation (RAP). by Jae Hyung Lee (1703224)

“…The patient received a single bevacizumab injection with gas/rt-PA injection. (E) Then, 2 months later, an RPE tear developed (arrowheads) and best-corrected visual acuity of the left eye decreased to counting fingers.…”

The numbers of upregulated and downregulated genes in the right and left mantles compared with the control right and left mantles on each of the seven sampling dates. by Xiaotong Wang (276499)

“…<p>In the right mantle, the number of upregulated or downregulated genes (green and purple bars, respectively) were determined at 1, 2, 3, 4, 5, 6 and 7 sampling dates. The levels gradually decreased with the increase of sampling dates, as expected if upregulation or downregulation were caused by random variation. …”

The LC dataset augments functional predictions by Teresa Reguly (21205)

“…</p><p></p> Evaluation of curated literature against GO biological process as a standard. Comparisons of enrichment for functional relationships in LC dataset versus a variety of HTP datasets as scored against GO biological process are shown as the individual data points. …”

The assay responds to stimulation of the T cells and to a known biologic. by Kasper Vadstrup (402463)

“…<p>(A) Cytokine release from inflamed colonic biopsies incubated with either anti-CD3 (10 μg/ml) or isotype control (10 μg/ml) in the explant assay for 24 hours (n = 12 patients, 2–4 biopsies each). Significant differences are observed for GM-CSF, IFN-γ and TNF-α (paired t-test) as well as across the panel, <i>P</i> = .0026 (two-way ANOVA). …”

Image1_A Novel Biochemical Study of Anti-Dermal Fibroblast Replicative Senescence Potential of Panax Notoginseng Oligosaccharides.tif by Lu Zhai (2069098)

“…Mechanistically, PNO treatment up-regulated expression of proliferating cell nuclear antigen (PCNA), cyclin E, cyclin D1, and cyclin-dependent kinase 4 (CDK4) proteins and promoted phosphorylation of MEK, p38, and ERK1/2 to trigger cell cycle progression. …”

Data_Sheet_1_β-Defensin 129 Attenuates Bacterial Endotoxin-Induced Inflammation and Intestinal Epithelial Cell Apoptosis.docx by Kunhong Xie (6998816)

“…Importantly, pBD129 elevated the expression level of Bcl-2-associated death promoter (Bcl-2), but down-regulated the expression levels of apoptosis-related genes such as the B-cell lymphoma-2-associated X protein (Bax), BH3-interacting domain death agonist (Bid), cysteinyl aspartate-specific proteinase-3 (Caspase-3), and caspase-9 in the intestinal mucosa (P < 0.05). …”

Progression of centromere coupling in wild-type diploid yeast cells. by Philippe Lefrançois (102385)

“…Heatmaps were unscaled, with white meaning no changes, red for increases, and blue for decreases. Please note the log2 scale on the color key for interaction frequencies. …”

Image_1_β-Defensin 129 Attenuates Bacterial Endotoxin-Induced Inflammation and Intestinal Epithelial Cell Apoptosis.TIF by Kunhong Xie (6998816)

“…Importantly, pBD129 elevated the expression level of Bcl-2-associated death promoter (Bcl-2), but down-regulated the expression levels of apoptosis-related genes such as the B-cell lymphoma-2-associated X protein (Bax), BH3-interacting domain death agonist (Bid), cysteinyl aspartate-specific proteinase-3 (Caspase-3), and caspase-9 in the intestinal mucosa (P < 0.05). …”

Acoustic parameters of voices of women in post-menopause by Renata D'Arc Scarpel (12818055)

“…CONCLUSION: The observed changes in acoustic parameters show that postmenopausal women had changes in vocal patterns, which can lead to decreased quality of life. Therefore, it requires a closer look at the need of speech therapy in this group.…”

Fibrotic changes in the murine lungs and livers of the DMSO, valsartan, and PD123319 groups. by Saori Yaguchi (418831)

“…<p>A: Mallory staining of the murine cGVHD lungs showing severe fibrosis of the interstitial space. …”

Image_1_The effect of calcitriol on the development and implantation capacity of embryos from hyper-stimulated mice.jpeg by Zoltán Bognár (16628382)

“…Calcitriol was given to superovulated female mice at the time of FSH injection (Group A), or at day 0.5 of pregnancy (Group B). The retrieved and cultured embryos were transferred to the uteri of pseudopregnant females. …”

The functional effects of three novel human isoforms, GABAB1k, l, and m. by Changhoon Lee (360362)

“…After one-way ANOVA and Dunnett's tests, one-tailed unpaired Student's t-tests were performed between no isoform injected groups and the isoform injected groups. A. GABAB1k had no inhibitory effect. B. GABAB1l data showed significant differences by ANOVA and Dunnett's tests (p = 0.0058), and caused significantly decreased GIRK currents at 5× and 6× GABAB1l (**p = 0.0014 and *p = 0.0229, respectively). …”

APOPTOSIS, NUTRITION, AND METABOLISM OF TRANSPLANTED INTERVERTEBRAL DISC CELLS by Morgan B. Giers (4395523)

“…The cells of the control decreased in viability and number over the 5 days without feeding, then improved dramatically when feeding was resumed. …”

DataSheet_1_Retinoic Acid Alleviates Cisplatin-Induced Acute Kidney Injury Through Activation of Autophagy.docx by Junxia Wu (8601516)

“…<p>Cisplatin-induced acute kidney injury (CIAKI) is a common complication in patients receiving cisplatin-based chemotherapy. …”

Image_1_Retinoic Acid Alleviates Cisplatin-Induced Acute Kidney Injury Through Activation of Autophagy.tif by Junxia Wu (8601516)

“…<p>Cisplatin-induced acute kidney injury (CIAKI) is a common complication in patients receiving cisplatin-based chemotherapy. …”

HLA Associations in Classical Hodgkin Lymphoma: EBV Status Matters by Xin Huang (11077)

“…The allele frequency of HLA-A2 was significantly decreased in the EBV+ cHL population. …”

Fig 2 - by Jeffery Demers (5607548)

“…<p>(a) Single-site basic reproduction number values as a function of the relative controlled death rate <i>μ</i>_<i>i</i>/<i>μ</i>₀ and relative controlled emergence rate Λ_<i>i</i>/Λ₀, assuming model parameters given in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1008136#pcbi.1008136.t001" target="_blank">Table 1</a>. …”

<i>Tg(slc17a6b)</i>-positive pretectal neurons are required for AF7 formation. by Alexandra R. Schmidt (18452108)

“…LPr = left pretectum. <b>(C-C</b>^<b>ii</b><b>)</b> Pre-ablation of 72 hpf max projection of 2-photon z-stack through RPr separated by individual channels of <i>Tg(atoh7</i>:<i>eGFP)</i>, green, <i>Tg(slc17a6b</i>:<i>DsRed)</i>, magenta, and merged image channels. …”

Data_Sheet_1_Quantitative Comparison of Pyranose Dehydrogenase Action on Diverse Xylooligosaccharides.PDF by Johanna Karppi (8364939)

“…A versatile method based on product reduction using sodium borodeuteride, and applicable to carbohydrate oxidoreductases in general, was established to facilitate the identification and quantification of oxidized products. …”

Data_Sheet_1_Characterization of Plasma Protein Alterations in Pregnant and Postpartum Individuals Living With HIV to Support Physiologically-Based Pharmacokinetic Model Developmen... by Sherry Zhao (3188103)

“…Estimated AAG concentrations slightly decreased from 24 wks gestation to term (53.6 and 44.9 mg/dL) while postpartum levels were elevated at two wks after delivery (126.1 mg/dL) and subsequently declined thereafter. …”