Supplementary Material for: <b><i>Uncaria rhynchophylla</i></b> Ameliorates Parkinson’s Disease by Inhibiting HSP90 Expression: Insights from Quantitative Proteomics by Lan Y.-L. (5438138)

“…<b><i>Background/Aims:</i></b> <i>Uncaria rhynchophylla</i>, known as “Gou-teng”, is a traditional Chinese medicine (TCM) used to extinguish wind, clear heat, arrest convulsions, and pacify the liver. …”

Image_1_Higher risk of cardiovascular mortality than cancer mortality among long-term cancer survivors.JPEG by Zhipeng Wang (154599)

“…</p>Results<p>For patients with cancer at all sites, the P_CV increased from 22.8% in the 5th year after diagnosis to 31.0% in the 10th year and 35.7% in the 20th year, while the P_CA decreased from 57.7% in the 5th year after diagnosis to 41.2 and 29.9% in the 10th year and 20th year, respectively. …”

Table_1_Higher risk of cardiovascular mortality than cancer mortality among long-term cancer survivors.docx by Zhipeng Wang (154599)

“…</p>Results<p>For patients with cancer at all sites, the P_CV increased from 22.8% in the 5th year after diagnosis to 31.0% in the 10th year and 35.7% in the 20th year, while the P_CA decreased from 57.7% in the 5th year after diagnosis to 41.2 and 29.9% in the 10th year and 20th year, respectively. …”

Image_3_Higher risk of cardiovascular mortality than cancer mortality among long-term cancer survivors.JPEG by Zhipeng Wang (154599)

“…</p>Results<p>For patients with cancer at all sites, the P_CV increased from 22.8% in the 5th year after diagnosis to 31.0% in the 10th year and 35.7% in the 20th year, while the P_CA decreased from 57.7% in the 5th year after diagnosis to 41.2 and 29.9% in the 10th year and 20th year, respectively. …”

Psychometric functions for the power-function transducer with nonzero pedestal. by Keith A. May (350981)

“…This figure illustrates two effects. Within each panel, we see how the psychometric function for the power-function transducer converges towards that for a log transducer as the exponent decreases (Theorem 4). …”

DataSheet1_pH-sensitive charge-conversion cinnamaldehyde polymeric prodrug micelles for effective targeted chemotherapy of osteosarcoma in vitro.docx by Jiapeng Deng (12046829)

“…</p><p>Results: An amphiphilic cinnamaldehyde polymeric prodrug [mPEG-b-P(C7-co-CA)] was successfully synthesized and self-assembled into spheric micelles with a diameter of 227 nm. The CMC value of mPEG-b-P(C7-co-CA) micelles was 25.2 mg/L, and it showed a pH dependent release behavior of CA. mPEG-b-P(C7-co-CA) micelles can achieve chargeconversion from a neutral to a positive charge with decreasing pHs. …”

Mechanical properties and surface characteristics of an AA6060 alloy strained in tension at cryogenic and room temperature by Xu, Zebing

“…When the temperature decreases, the yield strength, the ultimate tensile strength and ductility to fracture are drastically increased from 217.2 MPa, 252.4 MPa, 14.5% to 251.6 MPa, 335.9 Mpa, 21.5% respectively, and the average diameter of dimples decreases from ~8 µm to ~3 µm. …”
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Hemodynamic Forces Regulate Developmental Patterning of Atrial Conduction by Michael C. Bressan (674014)

“…Interestingly, mechanical loading of the embryonic atrial muscle resulted in an induction of <i>Cx40</i>, <i>Nav1.5</i> and the cell cycle marker <i>Cyclin D1,</i> while decreasing atrial pressure via <i>in vivo</i> ligation of the vitelline blood vessels results in decreased atrial conduction velocity. …”

Pharmacological Targeting the REV-ERBs in Sleep/Wake Regulation - Fig 2 by Ariadna Amador (2560231)

“…(<b>B</b>) SR9009 increased wakefulness, but only reached significance on day 3 (p<0.05), decreased SWS on days 2 and 3 (p<0.05), and decreased REM on day 3 (<b>C</b>) Overall, SR9009 increased SWS latency (F(1,5) = 7.7, p<0.05, only significant on Day 2 p = 0.02). …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. Exposure of macrophages to AaCdt slowed phagosome maturation and decreased phago-lysosome formation, thereby compromising macrophage phagocytic function. …”

Image_1_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. Exposure of macrophages to AaCdt slowed phagosome maturation and decreased phago-lysosome formation, thereby compromising macrophage phagocytic function. …”

The impact of Livin on cell cycle arrest in human colorectal cancer cells. by Dae-Seong Myung (452996)

“…Overexpression of Livin inhibited 5-FU-induced cell cycle arrest in SW480 cells and had a minimal influence in DKO1 cells. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. Exposure of macrophages to AaCdt slowed phagosome maturation and decreased phago-lysosome formation, thereby compromising macrophage phagocytic function. …”

Image_2_Aggregatibacter actinomycetemcomitans cytolethal distending toxin modulates host phagocytic function.tiff by Taewan J. Kim (16910679)

“…We now demonstrate that AaCdt manipulates the phosphoinositide (PI) pools of phagosome membranes and alters Rab5 association. Exposure of macrophages to AaCdt slowed phagosome maturation and decreased phago-lysosome formation, thereby compromising macrophage phagocytic function. …”

Supplementary Material for: Avelumab in Combination with Axitinib as First-Line Treatment in Patients with Advanced Hepatocellular Carcinoma: Results from the Phase 1b VEGF Liver 1... by Kudo M. (3218334)

“…Grade 3 treatment-related adverse events (TRAEs) occurred in 16 patients (72.7%); the most common (≥3 patients) were hypertension (<i>n</i> = 11 [50.0%]), palmar-plantar erythrodysesthesia syndrome (<i>n</i> = 5 [22.7%]), and decreased appetite (<i>n</i> = 3 [13.6%]). …”

D-PDMP reduced tumor volume in mice. by Subroto Chatterjee (411621)

“…The right kidney served as control, and the left kidney served as placebo or drug treated with 3 and 10 MPK of D-PDMP. <b>A</b>: A marked increase in mouse kidney tumor volume is sharply decreased by feeding D-PDMP. …”

Table_2_pH Responsive Polymer Micelles Enhances Inhibitory Efficacy on Metastasis of Murine Breast Cancer Cells.DOCX by Jie Wang (16762)

“…The size, drug loading content, and encapsulation efficiency of PTX loaded micelles were 20–30 nm, 7.5%, 82.5%, respectively. PTX loaded PELA-PBAE micelles could enhance the intracellular uptake of a model drug significantly, with increased cytotoxicity and inhibition of tumor metastasis on 4T1 cells, as confirmed by wound healing assay and tumor cells invasion assay. …”

Effect of soybean meal replacement by slow-release urea on ruminal parameter, blood metabolites, and microbial protein synthesis in Zel ram by Zahra Alizadeh (9303946)

“…The experimental design was a 4×4 Latin square design. The experiment has consisted of the following four rations: 1) basic diet with soybean meal as a protein source, 2) basic diet with soybean meal plus 0.5 % of DM slow-release urea (SRU), 3) basic diet with soybean meal plus 1 % of DM SRU, and 4) basic diet with soybean meal plus 1.5 % of SRU, respectively. …”

Expression profiles of mRNA markers of cardiac phenotypes. by Trond Brattelid (290970)

“…(A) Expression of ANP mRNA increases at birth and in HF; (B) MHC-α mRNA expression increases at birth and during transition from neonatal to adult and decreases in HF; (C) MHC-β mRNA expression demonstrates a transitional increase at birth and an increase in HF; (D) The ratio of MHC-β over MHC-α mRNA expression confirms transition in phenotype from foetal to adult and from Sham to HF. …”

Table_1_pH Responsive Polymer Micelles Enhances Inhibitory Efficacy on Metastasis of Murine Breast Cancer Cells.DOCX by Jie Wang (16762)

“…The size, drug loading content, and encapsulation efficiency of PTX loaded micelles were 20–30 nm, 7.5%, 82.5%, respectively. PTX loaded PELA-PBAE micelles could enhance the intracellular uptake of a model drug significantly, with increased cytotoxicity and inhibition of tumor metastasis on 4T1 cells, as confirmed by wound healing assay and tumor cells invasion assay. …”