Increasing Notch1 activity in MAFs suppresses tumor angiogenesis. by Hongwei Shao (493627)

“…Data are mean ± SD, n = 5 tumors/group. <b>B.</b> Significantly decreased blood vessel density is observed in 1205Lu co-grafted with N1^IC-GFP/MAF. …”

Immunohistochemical staining and quantitative analysis for VEGF, PEDF, MMP-2, MMP-9, and MMP-14 in human CNE-2 xenograft tissues. by Fang Peng (327071)

“…<p>Xenografts were harvested at day 5 after treatment initiation. The levels of VEGF, MMP-2, MMP-9 and MMP-14 were decreased, while the level of PEDF was increased in CNE-2 xenografts treated with endostar for 5 days compared with the control group (Student's t-tests). a–c, VEGF staining and quantitative data; d–f, PEDF immunostaining and quantitative data; g–i, MMP-2 immunostaining and quantitative data; j–l, MMP-9 immunostaining and quantitative data; m–o, MMP-14 immunostaining and quantitative data. n = 6/group. …”

Global disease burden attributed to low physical activity in 204 countries and territories from 1990 to 2019: Insights from the Global Burden of Disease 2019 Study by Ammar, Achraf

“…In 2019, low PA seems to contribute to 0.83 million [95% uncertainty interval (UI) 0.43 to 1.47] deaths and 15.75 million (95% UI 8.52 to 28.62) DALYs globally, an increase of 83.9% (95% UI 69.3 to 105.7) and 82.9% (95% UI 65.5 to 112.1) since 1990, respectively. The age-standardized rates of low-PA-related deaths and DALYs per 100,000 people in 2019 were 11.1 (95% UI 5.7 to 19.5) and 198.4 (95% UI 108.2 to 360.3), respectively. …”
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DataSheet_1_Genome-wide identification of NHX (Na+/H+ antiporter) gene family in Cucurbita L. and functional analysis of CmoNHX1 under salt stress.xlsx by Changwei Shen (9317979)

“…The findings demonstrated that during salt stress, A. thaliana that had CmoNHX1 heterologously expression was found to have decreased salt tolerance. …”

Image_1_Genome-wide identification of NHX (Na+/H+ antiporter) gene family in Cucurbita L. and functional analysis of CmoNHX1 under salt stress.tif by Changwei Shen (9317979)

“…The findings demonstrated that during salt stress, A. thaliana that had CmoNHX1 heterologously expression was found to have decreased salt tolerance. …”

Data Sheet 1_Wedelia trilobata-derived biochar mitigates chromium toxicity and improves physiological performance in hydroponically grown Chinese cabbage.docx by Fengyue Qin (21748557)

“…Chromium (Cr) toxicity is a major abiotic stressor that threatens leafy vegetable productivity and food safety.…”

Synthesis and Calorimetric, Spectroscopic, and Structural Characterization of Isocyanide Complexes of Trialkylaluminum and Tri-<i>tert</i>-butylgallium by Nicholas B. Kingsley (2112355)

“…Addition of <i>tert</i>-butylisocyanide or 2,6-dimethylphenylisocyanide to a solution of trialkylaluminum or trialkylgallium results in formation of complexes R₃M·CN^tBu (M = Al, R = Me (<b>1</b>), Et (<b>2</b>), ⁱBu (<b>3</b>), ^tBu (<b>4</b>); M = Ga, R = ^tBu (<b>9</b>)) or R₃M·CN­(2,6-Me₂C₆H₃) (M = Al, R = Me (<b>5</b>), Et (<b>6</b>), ⁱBu (<b>7</b>), ^tBu (<b>8</b>); M = Ga, R = ^tBu (<b>10</b>)), respectively. …”

Image_2_Genome-wide identification of NHX (Na+/H+ antiporter) gene family in Cucurbita L. and functional analysis of CmoNHX1 under salt stress.tif by Changwei Shen (9317979)

“…The findings demonstrated that during salt stress, A. thaliana that had CmoNHX1 heterologously expression was found to have decreased salt tolerance. …”

Table_1_Effects of dietary Chinese yam polysaccharide copper complex on growth performance, immunity, and antioxidant capacity of broilers.docx by Jinzhou Zhang (386968)

“…In addition, the antioxidative gene mRNA expression of Nuclear factor E2-related factor 2 (Nrf₂), Superoxide dismutase 1 (SOD₁), Superoxide dismutase 2 (SOD₂), and Catalase (CAT) were upregulated in the liver (P < 0.05). …”

Activin expression network at ovulation. by Christopher J. Martyniuk (243374)

“…Red indicates that the gene is increased and green indicates that the gene is decreased. The abbreviations are provided in the supplementary abbreviation list (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0059093#pone.0059093.s005" target="_blank">File S5</a>).…”

Activation of the RSC-ACC projections causes mechanical and thermal pain sensitization. by Shun Hao (11848871)

“…<b>(E and H)</b> Blue-light stimuli do not change the tail-flick response latency significantly in both ChR2 and EYFP mice (two-tailed paired <i>t</i> test, ChR2: <i>t</i> = 0.9925, <i>p</i> = 0.35, <i>n =</i> 9 mice; EYFP: <i>t</i> = 1.133, <i>p</i> = 0.29, <i>n =</i> 9 mice). …”

Open Field. by Raina D. Pang (345662)

“…<p>A) 5-HTT KO mice show significantly decreased distance traveled throughout the arena in a novel open field. …”

Western blot analysis for ACE2 protein expression in urine and ACE2, ADAM17 and TIMP3 protein expression in the kidney of <i>db/db</i>, <i>db/db</i>+rosiglitazone mice. by Harshita Chodavarapu (408580)

“…<p>(A) Western blot analysis for ACE2 protein expression in urine. …”

HDAC6 differentially regulates autophagy in stem-like versus differentiated cancer cells by Tanveer Sharif (329961)

“…Mechanistically, HDAC6 KD in CSCs decreases pluripotency by promoting autophagy, whereas the inhibition of pluripotency via retinoic acid treatment, POU5F1 or autophagy-related gene (<i>ATG7</i> and <i>ATG12</i>) KD in CSCs decreases HDAC6 expression and promotes differentiation. …”

Data Sheet 1_Effects of chili straw on rumen fermentation, meat quality, amino acid and fatty acid contents, and rumen bacteria diversity in sheep.docx by Jinlong Li (388896)

“…Fifty F1 Dorper×Hu lambs (29.58 ± 2.06 kg) were randomly assigned to five groups, fed pelleted feed with 0%, 5%, 10%, 15%, or 20% CS over a 63-day period, including a 7-day pre-test. …”

Data_Sheet_1_Association of folate and vitamin B12 imbalance with adverse pregnancy outcomes among 11,549 pregnant women: An observational cohort study.doc by Xiaosong Yuan (6683027)

“…A higher SFVB12R increased birthweight (β 60.99; 95% CI 29.52–92.45) and was associated with a higher risk of large-for-gestational-age (LGA) newborns (OR 3.08; 95% CI 1.63–5.83); a lower SFVB12R decreased birthweight (β −43.81; 95% CI −75.62, −12.00) and was associated with a lower risk of LGA newborns (OR 0.75; 95% CI 0.56–1.00), and with higher risks of ICP (OR 2.03; 95% CI 1.54–2.67) and pregnancy-induced hypertension (PIH, OR 1.81; 95% CI 1.09–3.00).…”

Data_Sheet_1_Proportion and trend in the age of cigarette smoking initiation among adolescent smoking experiencers aged 13–15 years in 148 countries/territories.doc by Shuhui Xing (14181710)

“…</p>Results<p>Among 99,728 adolescent smoking experiencers aged 13–15 years, the proportions of initiating cigarette smoking when aged ≤ 9 years, 10–11 years, 12–13 years, and 14–15 years were 22.8% (95%CI 21.3–24.4), 18.8% (17.3–20.2), 36.8% (34.5–39.2), and 21.6% (19.9–23.2), respectively. The average age of cigarette smoking initiation decreased by 0.44 years per 5 calendar-years averagely in 17 (11.5%) of 148 countries, was unchanged in 95 (64.2%) countries, and increased by 0.38 years per 5 calendar-years averagely in 36 (24.3%) countries. …”

Interactions between Notch and Wnt signaling during the activation of Müller cells. by Carolina Beltrame Del Debbio (243080)

“…The proportion of SP cells increased to 0.5% in retinal explants treated with Jag1+Wnt3a (<b>D</b>), which was decreased to 0.1% (<b>E</b>) when DAPT was added to the culture, suggesting a synergistic interaction between Notch and Wnt signaling in the activation of SP cell phenotype in Müller cells (<b>F</b>).…”

Effects of Dietary Supplementations of Synbiotics on Growth Performance, Carcass Characteristics and Nutrient Digestibility of Broiler Chicken by H Nisar (12803445)

“…The experimental diets were supplemented with 0, 700, 1200, 1700 or 2200 g/ton of feed synbiotics and respectively designated as A, B, C, D and E, with A being the control diet. …”

Attenuated transcription for <i>Hox</i> genes moved towards the centromeric end of the cluster. by Patrick Tschopp (266480)

“…<p>Expression patterns of <i>Hoxd3</i>, <i>Hoxd4</i> and <i>Hoxd9</i> in embryos carrying deletions in 5′ of these genes. Schemes and colors are as for <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1000398#pgen-1000398-g003" target="_blank">Figure 3</a>. …”