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101501
Image3_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF
Published 2024“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkably decreased thresholds of weight bearing and paw withdrawal, alterations in the tibial and femoral structures (reactive sclerosis, increased trabeculation, and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining and tidemark integrity, and increased synovial hyperplasia and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord. …”
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101502
DataSheet_1_Genetically Predicted C-Reactive Protein Associated With Postmenopausal Breast Cancer Risk: Interrelation With Estrogen and Cancer Molecular Subtypes Using Mendelian Ra...
Published 2021“…Estrogen-only users for ≥5 years had more profound CRP-decreased breast cancer risk in dose–response fashion, whereas past OC users for ≥5 years had CRP-increased cancer risk. …”
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101503
Image2_Novel multitarget analgesic candidate SZV-1287 demonstrates potential disease-modifying effects in the monoiodoacetate-induced osteoarthritis mouse model.TIF
Published 2024“…Then, SZV-1287 (20 mg/kg/day) or its vehicle was injected intraperitoneally over a 21-day period.</p>Results<p>MIA induced remarkably decreased thresholds of weight bearing and paw withdrawal, alterations in the tibial and femoral structures (reactive sclerosis, increased trabeculation, and cortical erosions), histopathological damage (disorganized cartilage structure, hypocellularity, decreased matrix staining and tidemark integrity, and increased synovial hyperplasia and osteophyte formation), and changes in the astrocyte and microglia density in the lumbar spinal cord. …”
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101504
Long-term use of cover crops and no-till shift soil microbial community life strategies in agricultural soil
Published 2018“…Total (bacterial + archaeal) diversity was higher in no-till than standard till; diversity increased with depth in no-till but decreased with depth in standard till. Total bacterial numbers were higher in cover cropped plots at all depths, while no-till treatments showed higher numbers in 0–5 cm but lower numbers at lower depths compared to standard tillage. …”
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101505
The effect of degradation rate of macromolecules on strand asymmetry.
Published 2014“…For strong trade-off (), this threshold is at a lower rate of degradation, whereas higher degradation rates are tolerated as the strength of trade-off decreases (). …”
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101506
Effects of enalapril and paricalcitol treatment on diabetic nephropathy and renal expressions of TNF-α, p53, caspase-3 and Bcl-2 in STZ-induced diabetic rats
Published 2019“…In association, the immunohistochemically detected pro-inflammatory cytokine, TNF-α, and apoptotic mediators, p53 and caspase-3, were remarkably decreased in kidney of diabetic rats as a result of treatment while the expression of anti-apoptotic protein Bcl-2 was increased. …”
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101507
The impact of using chickpea flour and dried carp fish powder on pizza quality
Published 2017“…Chickpea flour increased iron and zinc contents of the pizza. Water activity (<i>a</i><sub>w</sub>) was decreased in fish powder and chickpea pizza. …”
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101508
Data_Sheet_1_Optimizing Nutrient Recycling From Excreta in Sweden and Pakistan: Higher Spatial Resolution Makes Transportation More Attractive.docx
Published 2019“…Further increasing the resolution to 5 km grids in Sweden decreased the average transportation distance by 9 km (down to 123 km). …”
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101509
Data_Sheet_1_Optimizing Nutrient Recycling From Excreta in Sweden and Pakistan: Higher Spatial Resolution Makes Transportation More Attractive.docx
Published 2019“…Further increasing the resolution to 5 km grids in Sweden decreased the average transportation distance by 9 km (down to 123 km). …”
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101510
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101511
Influence of RhoB in 786-O cells and Caki-1 cells on cell cycle distribution.
Published 2016“…(<b>B, D</b>) The data were shown mean±SD of three independent experiments, each performed in triplicate. (<b>E</b>) The expression levels of cyclin B1 and CDK1 were significantly decreased in 786-O cells transfected with pcDNA3.0-Flag-RhoB (<i>p</i><0.05). …”
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101512
Time of treatment initiation affects disease rebound and therapeutic outcome.
Published 2024“…Infected host cells and activated CD8<sup>+</sup> T cells are normalized by division with their initial values 14.46x10<sup>6</sup> [1/ml] and 0.4 [g/cm<sup>3</sup>], respectively. (E) indicates that increasing the expression of proinflammatory cytokines (by 1000-fold), decreases the peak number of infected cells with prolonged hypoxemia (F) the optimal timing for avoiding rebound or qualitatively effecting the degree of activated B cells (G) or activation of CD4 and CD8 T-cells (H).…”
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101513
Figure 1 from Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
Published 2025“…<b>F,</b> Under hypoxia (3% O<sub>2</sub>), OCR ablation was observed at 1 µmol/L atovaquone and while a trend toward reduced OCR was observed for banoxantrone this was not significant.…”
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101514
Image_1_EEG Signal Complexity Is Reduced During Resting-State in Fragile X Syndrome.TIF
Published 2022“…</p><p>Methods: In this study, resting-state EEG power, including alpha peak frequency (APF) and theta/beta ratio (TBR), as well as signal complexity using multi-scale entropy (MSE) were compared between 26 FXS participants (ages 5–28 years), and 77 neurotypical (NT) controls with a similar age distribution. …”
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101515
Table_1_EEG Signal Complexity Is Reduced During Resting-State in Fragile X Syndrome.docx
Published 2021“…</p><p>Methods: In this study, resting-state EEG power, including alpha peak frequency (APF) and theta/beta ratio (TBR), as well as signal complexity using multi-scale entropy (MSE) were compared between 26 FXS participants (ages 5–28 years), and 7 neurotypical (NT) controls with a similar age distribution. …”
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101516
Table_1_EEG Signal Complexity Is Reduced During Resting-State in Fragile X Syndrome.docx
Published 2022“…</p><p>Methods: In this study, resting-state EEG power, including alpha peak frequency (APF) and theta/beta ratio (TBR), as well as signal complexity using multi-scale entropy (MSE) were compared between 26 FXS participants (ages 5–28 years), and 77 neurotypical (NT) controls with a similar age distribution. …”
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101517
Image_1_EEG Signal Complexity Is Reduced During Resting-State in Fragile X Syndrome.TIF
Published 2021“…</p><p>Methods: In this study, resting-state EEG power, including alpha peak frequency (APF) and theta/beta ratio (TBR), as well as signal complexity using multi-scale entropy (MSE) were compared between 26 FXS participants (ages 5–28 years), and 7 neurotypical (NT) controls with a similar age distribution. …”
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101518
Figure S1 - Synergistic and Additive Effects of Epigallocatechin Gallate and Digitonin on <em>Plasmodium</em> Sporozoite Survival and Motility
Published 2010“…We reduced it to 1% since the percentage of sporozoite gliding is still similar. However, decreasing the BSA concentration further resulted in a drastic reduction of gliding parasites. …”
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101519
Increased extrinsic mortality results in lower intrinsic mortality.
Published 2017“…<p>(A) Adding an additional source of extrinsic mortality of magnitude <i>Q</i> decreases the evolved value of intrinsic mortality <i>q</i>, and increases evolved reproduction probability <i>p</i>. …”
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101520
Effects of Maraviroc and Efavirenz on Markers of Immune Activation and Inflammation and Associations with CD4<sup>+</sup> Cell Rises in HIV-Infected Patients
Published 2010“…term=MERIT&cond=HIV&rank=1">NCT00098293</a></p></div>…”