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Ether induces proteotoxic stress, leading to a decrease in Trx protein and an increase in Hsp90 clients that are joint targets of Trx and Ubx.
Published 2024“…Representative images (10×) of untreated eggs (top) and eggs that were exposed to ether vapor for 2 h (bottom). <b>(F)</b> Representative images of Acridine Orange-stained <i>yw</i> embryos for the following cases: no treatment (up left), 5-min immersion in Citrasolv solution [<a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3002629#pbio.3002629.ref046" target="_blank">46</a>] (up right), 5-min immersion in ether liquid (bottom right), and 1.5-h exposure to ether vapor (bottom left). …”
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PLD inhibitors decrease PLD2 expression in foci of lungs following xenotransplantation.
Published 2016“…(<b>F</b>) Xenotransplanted with Alzet pumps delivering vehicle FIPI or (<b>G</b>) VU0155072-2. Scale bar = 200 μm. (<b>H</b>) ImageJ quantification of the negative effect of PLD inhibitors on total mean fluorescence of the total area of PLD2 positive foci in lung tissues in terms of μm<sup>2</sup> x 10<sup>3</sup>. …”
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