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Inhibition of MRP1 significantly decreases basal and apoptotic GSH efflux.
Published 2012“…<p>GSH efflux in ARPE-19 cells incubated with two MRP1 inhibitors (75 µM MK571 and 5 mM sulfinpyrazone [SP]) for 5 h (A). …”
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564
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565
The number of behavioral arrests in DKO mice decreased following systemic atropine.
Published 2011“…<p>(A) Mean (± SEM) time per mouse spent in full behavioral arrests are plotted in 30 min bins across the entire recording period following IP injections of saline (open symbols) and atropine (0.5 mg/kg; filled symbols). …”
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566
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567
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Down-regulation of Gli decreased ovarian cancer cell migration and invasion.
Published 2014“…<p>(<b>A</b>) Exposure to GANT61 (30 µM; 48 hr) reduces expression of both Gli1 and Gli2 protein, determined by Western blot. …”
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569
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570
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571
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572
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Survivin deletion in beta cells leads to decreased beta-cell mass.
Published 2012“…<p>(a) Male and female mutant mice exhibit decreased beta-cell mass at 2-month of age as compared to controls (n = 5 per genotype). …”
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577
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578
Downregulation of SPHK1 expression decreases the resistance of glioma cells to apoptosis.
Published 2013“…Results are expressed as percentages of total cells. (E) PARP cleavage and cleaved caspase 3 levels were assessed in indicated cell lines treated with UV irradiation (40 J/m<sup>2</sup>) or adriamycin (1.0 µM) for 24 h via WB. α-tubulin was used as a loading control. …”
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579
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580