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Overexpression of cathepsin K in mice decreases collagen deposition and lung resistance in response to bleomycin-induced pulmonary fibrosis-2
Published 2011“…Nized and BAL cells (A, B), freshly isolated type II alveolar epithelial cells (A, C), lung homogenate (A, D), and concentrated BAL fluid supernatant (E) were prepared for analysis of cath K mRNA by real-time RT-PCR (A) and western blotting (B-E). …”
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At lower concentrations, METH decreases LTP.
Published 2010“…At 0.1 µM METH, LTP was 1.58±.08 [<i>n</i> = 13(5)] (Fig. 1B); at 1 µM METH, LTP was 1.50±.07 [<i>n</i> = 13(7)] (Fig. 1C); at 10 µM METH, LTP was 1.58±.07 [<i>n</i> = 14(8)] (Fig. 1D); at 30 µM METH, LTP was 1.37±.06 [<i>n</i> = 15(4)] (Fig. 1E); and at 60 µM METH, LTP was 1.32±.24 [<i>n</i> = 4(2)] (Fig. 1E). …”
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Overexpression of Pax6 decreases Olig2 protein levels.
Published 2011“…(<b>a</b>) Oli-Neu cells were transfected with flag-tagged WT Pax6 (WT), Pax6(5a)R128C (128), or eGFP control vector (-). …”
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Vasopressin decreases EPSPs in CA2 after LTP induction.
Published 2013“…</i> time showing that AVP did not affect the basal EC LIII-CA2 EPSP recorded before HFS stimulation. E) Left, Typical graph of the fEPSP evoked by Schaffer collaterals stimulation and recorded in a CA1 pyramidal neuron (SC-CA1); AVP did not affect the amplitude of the LTP-potentiated EPSP , as shown on the average graph (Right, n = 4).…”
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Regenerating axons are increased by ATRA and decreased by clodronate.
Published 2021“…<p>(A—E) Confocal images of immunohistochemical staining of growing axons with anti-GAP43 antibody (green), in longitudinal sections of the optic nerve at 2 weeks after axotomy. …”
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