Decreased Polycystin 2 Levels Result in Non-Renal Cardiac Dysfunction with Aging by Ivana Y. Kuo (707543)

“…Anatomically, the 9 month old Pkd2+/- mice had thinner left ventricular walls, consistent with dilated cardiomyopathy, and the left ventricular ejection fraction was decreased. Intriguingly, in response to acute isoproterenol stimulation to examine β-adrenergic responses, the 9 month old Pkd2+/- mice exhibited a stronger contractile response, which also coincided with preserved localization of the β2 adrenergic receptor. …”

HIF-1α knockdown and TGF-β blockade decreases VEGF and CXCR4 mRNA expression <i>in vitro</i>. by Lauren K. Dunn (260121)

G3BP1 and TIA-1 double-KD cells, which had decreased MuV-induced SGs, partly increased MuV-induced IFN-λ1 production, but did not affect MuV replication. by Shin Hashimoto (3079659)

The human neutrophil IL-1β secretory response, in contrast to the CXCL8/IL-8 secretory response decreases as MOI increases. by Florencia Sabbione (4862455)

Manganase²⁺ stimulation decreases association of ADAM17 to β1 integrin and leads to increased ADAM17 activity. by Pal Gooz (330154)

<i>In vitro</i> characterization of the mnuA::Tn and 0690::Tn mutants. by Aga E. Gelgie (17661720)

Anesthetics differentially decrease cilia-driven particle transport speed (PTS). by Ghulam Murtaza (2559319)

“…<b>(D)</b> Avertin® (1 mM) decreased PTS. N = 5 tracheas from 5 animals. <b>(E)</b> Avertin® (4 mM) robustly decreased basal PTS and ATP could not induce increase in PTS. …”

Early HCV infection enhanced cell survival signaling pathways associated with TGF-β in hepatocytes while phosphorylated Gab1 decreased. by Da-eun Nam (18927946)

The BMP pathway decreases the ability of colonocytes to grow without anchoring. by Jacques Dupuy (6670244)

smPPARγOE decreased the transcripts of aortic smooth muscle contractile proteins and the smooth muscle transcriptional co-activator, myocardin. by Jennifer M. Kleinhenz (811618)

Berenil treatment decreases the percentage of CD25⁺ and FoxP3⁺ cells in the spleens of infected mice. by Shiby Kuriakose (121471)

Homozygous deletion of <i>ERG251</i> leads to increased sensitivity to cell membrane and osmotic stress but decreased sensitivity to oxidative stress. by Xin Zhou (54275)

NEURON computer modelling predicts increased electrical activity at rest and in response to hyperpolarizing pulses for three variants of Ca_V3.3 and quiescence at rest fo... by Yousra El Ghaleb (22075892)

Subjects:

Helminth co-infection results in decreased number of CD11b⁺ cells and antimicrobial peptide expression in colonic tissue. by Libo Su (596288)

Experiment 1: Comparison of effort and delay discounting. by Miriam C. Klein-Flügge (713481)

“…The sigmoidal model was included because it fulfills two particular features: it can obtain initially concave shapes, in line with work showing that the sense of effort increases as a power function of the target force with decreasing sensitivity at lower effort levels; and it entails a turning point after which effort discounting becomes progressively less steep. …”

Spatial training decreases the association between Ndfip1 and Nedd4 and decreases endogenous Beclin 1 ubiquitination in the hippocampus. by Wei-Lun Hsu (1756123)

“…Endogenous Beclin 1 ubiquitination level is decreased in Nedd4 siRNA-transfected rats (t_1,6 = 5.78, <i>p</i> = 0.001). …”

3-aminobenzamide decreased nuclear SIRT1 expression without modifying its activity, demonstrating basal SIRT1 activity increase. by Cindy Gueguen (526035)

Subtype C MA decreases viral production, only partially rescues viral replication in CD4+ T-cells but does not restore infectivity. by Eveline Santos da Silva (411217)

Exogenous IL-15 decreases the fraction but not the absolute number of CD25^High CD4⁺ T cells. by Tom L. Van Belle (306406)

TGFβ1 decreases p27 phosphorylation at Thr187 in the gastric mucosa of 14-day-old rats during fasting. by Ana P. Z. P. Fiore (593811)