Destabilization of a PKD Domain by the <i>Pkd1l1</i>^<i>rks</i> Mutation. by Daniel T. Grimes (2819494)

“…(E) Thermal denaturation analysis of PKD1L1 PKD domain 2: a reduced melting temperature (Tm) of 56.4°C is evident in the <i>rks</i>-mutated domain; in wild-type controls a Tm of 68.6°C is detected.…”

Comparative Study of Adsorbed Complexes inside Pores and Cavities of Acid Zeolites with Different Topology: Experimental and Theoretical Insights into Confinement Effects by Gonzalo David Romero Ojeda (18415001)

“…TG-FTIR for the first mass loss process, adsorption energy calculations, and electron density results show that the strength of the adsorption of acetic acid between the different acidic zeolites decreases in the order of H-MOR > H-ZSM-5 > H-Beta > H−Y. …”

SPARC has therapeutic potential in severely virus-induced heart failure. by Sophie Deckx (800206)

“…<p>A—D In the more severe VM model mice are injected with 10⁴ PFU CVB3, which results in severe cardiac inflammation after 1 week, and prominent fibrosis, but no cardiomyocyte hypertrophy after 5 weeks. …”

Enok is important for Rhi occupancies at Enok-dependent piRNA source loci. by Shih-Ying Tsai (3576587)

“…<b>(B)</b> Genome Browser view of Rhi ChIP-seq data shows that the Rhi levels at 42AB were decreased upon <i>enok</i> knockdown. Experimental details are as described in <a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009349#pgen.1009349.g005" target="_blank">Fig 5A</a>. …”

1561_pHW_Perth09-HA-G78D-T212I.gb by Valerie Le Sage (10669206)

“…In this study, we examined the role of HA pH of fusion on transmissibility of a cell-culture-adapted H3N2 virus. Mutations in the HA head at positions 78 and 212 of A/Perth/16/2009 (H3N2), which were selected after cell culture adaptation, decreased the acid stability of the virus from pH 5.5 (WT) to pH 5.8 (mutant). …”

Effect of TSC1 deficiency on B cell development in the spleen. by Xinxin Ci (168133)

“…Data shown represent or are calculated from at least five experiments with a total of ten mice in each group. …”

RNase-substrate binding sub-sites. by Khushboo Bafna (531726)

“…The substrates investigated in this study are 5’-ACAC-3’ (shown) and 5’-AUAU-3’. In the present work, simplified nucleotides numbering scheme A_(-2)C/U_(-1)A₍₁₎C/U₍₂₎ is used with negative numbers corresponding to nucleotides away from cleaved phosphodiester bond decreasing in the 5’ direction and positive numbers for nucleotides away from cleaved phosphodiester bond increasing in the 3’direction.…”

Precocity, yield and water-use efficiency of banana plants under planting densities and irrigation depths, in semiarid region by Marcelo Rocha dos Santos (6699794)

“…The hands weight and number of fruits decreased in a linear way with the increase in the planting density (1,600 plants ha-1 to 3,333 plants ha-1) from 10.89 kg to 9.49 kg and from 97.16 to 89.86, respectively; whereas the hands yield (15.5 t ha-1 to 25.79 t ha-1) and the harvest period (442 to 455 days) increased. …”

Effect of acute phenylalanine and tyrosine depletion (APTD) on startle eye-blink amplitudes to underweight and healthy female body stimuli (relative to neutral cues) in individuals... by Caitlin B. O’Hara (847826)

“…<p>In the balanced condition (BAL), AN REC showed decreased startle potentiation (an appetitive response) to underweight (5.18 ± 0.58) relative to neutral (5.30 ± 0.54) cues, while HC displayed increased startle potentiation (an aversive response) to underweight (5.35 ± 0.65) relative to neutral (5.19 ± 0.75) cues. …”

Effect of acute phenylalanine and tyrosine depletion (APTD) on startle eye-blink amplitudes to physically active and non-active body stimuli (relative to neutral cues) in individua... by Caitlin B. O’Hara (847826)

“…<p>In the balanced condition (BAL), AN REC tended towards decreased startle potentiation (an appetitive response) to active (5.21 ± 0.55) relative to non-active cues (5.30 ± 0.51), while HC displayed increased startle potentiation (an aversive response) to active (5.29 ± 0.68) relative to neutral (5.19 ± 0.75) cues. …”

Effect of a Stewardship Intervention on Adherence to Uncomplicated Cystitis and Pyelonephritis Guidelines in an Emergency Department Setting by Michelle T. Hecker (519160)

Mutation of putative JNK phosphorylation sites on hSIRT1 reduces phosphorylation and activity of SIRT1. by Nargis Nasrin (255515)

“…Cells were transfected with the empty vector (CMV), WT hSIRT1 (WT) or Mt-SIRT1 (Mt) then treated with H₂O₂ or H₂O₂ plus JNK inhibitor (JNKi). …”

Table 1_Multiparametric MRI assessment of renal blood oxygenation, fat content, and hemodynamics in an animal model of metabolic dysfunction-associated steatotic liver disease.docx by Chao Wang (146527)

“…Renal T2* and FF were significantly correlated with renal H&E scores and HIF-1α expression (|r| = 0.3552–0.7745). …”

Disruption of Spatacsin in mice results in a severe spastic and ataxic gait disorder. by Rita-Eva Varga (784560)

“…<b>(E)</b> Compared to control mice aged KO mice fall off the beam more frequently (n = 20; 2-way-ANOVA: p = 0.0157; Bonferroni post-hoc analysis: ** indicates p<0.01). …”

Effect of deferiprone on cell cytotoxicity. by Chhanda Bose (787135)

“…</b> Deferiprone treatment decreases the release of catalytic iron of Omniscan-treated human PBMC, as shown by use of a bleomycin-detectable iron assay. …”

Comparison between theories and simulations of the stochastic model. by Xiangrui Ji (16705908)

“…In (A-C), Δ<i>θ</i> = 0.1. (D) The intersection of <i>c</i>_act and (solid green line) determines the mean cell size at division 〈<i>V</i>_<i>d</i>〉. …”

Image_1_Cardioprotective Effect of Whole Body Periodic Acceleration in Dystrophic Phenotype mdx Rodent.TIFF by Arkady Uryash (711632)

“…Myocardial cells from dystrophin-deficient 15-month old mdx mice have contractile deficiency, which is associated with elevated concentrations of diastolic Ca²⁺ ([Ca²⁺]_d), Na⁺ ([Na⁺]_d), and reactive oxygen species (ROS), increased cell injury, and decreased cell viability. …”

Image_1_Dapagliflozin Attenuates Renal Tubulointerstitial Fibrosis Associated With Type 1 Diabetes by Regulating STAT1/TGFβ1 Signaling.TIF by Fengjuan Huang (6160181)

“…Furthermore, dapagliflozin improved renal function, and attenuated diabetes-induced TIF. In HK-2 cells, dapagliflozin, and fludarabine directly decreased aberrant STAT1 expression and reversed high glucose-induced downregulation of E-cadherin and α-SMA induction. …”

Activation of MEK1 during physiological cardiac hypertrophy inhibits PPARα activity. by Hamid el Azzouzi (318740)

“…(b) Western blot analysis using anti-phosphorylated ERK1/2 (p-ERK1/2) antibody on lysates of heart samples of indicated experimental procedure, showing reduced MEK1-ERK1/2 activity of exercised mice treated with U0126. …”

High Glucose Variability Increases 30-Day Readmission Rates in Patients with Type 2 Diabetes Hospitalized in Department of Surgery by Ching-jung Hsieh (728756)

“…Comparing to control group, the study group also had higher HbA1c (8.4 ± 1.3% vs. 7.7 ± 1.1%, <i>p</i> = 0.015) and LOS (8.5± 2.5 days vs 7.0± 1.5 days, <i>p</i> = 0.020). …”