Table1_Relationship between cathepsins and cardiovascular diseases: a Mendelian randomized study.xlsx by Qiaoqiao Li (355362)

“…</p><p>Conclusion: Our MR analysis reveals that cathepsin E is a risk factor for MI and IS, cathepsin L2 offers protective effects against CHF and AF, and cathepsin O increases the risk for IS and AF.…”

Image 1_Kaixin San Jiawei granule improves cognitive function and alleviates neuronal damage in Alzheimer’s disease via multi-component and multi-target mechanisms.tif by Wei Liu (20030)

“…Treatment increased hippocampal levels of ACh and GSH-Px while reducing AChE and ROS. In vitro, KSG mitigated Aβ_25-35-induced cytotoxicity in PC12 cells, decreased Aβ accumulation, and downregulated the expression of TNF-α and IL-1β. …”

Data_Sheet_1_Early Combination of Albumin With Crystalloid Administration Might Reduce Mortality in Patients With Cardiogenic Shock: An Over 10-Year Intensive Care Survey.pdf by Zhi-ye Zou (12651271)

“…Patients who received the albumin combination had decreased 30-day and 60-day mortality (21.7 vs. 32.4% and 25.2 vs. 34.2%, respectively, P < 0.001), and the results were robust after PSM (21.3 vs. 44.7% and 24.9 vs. 47.0%, respectively, P < 0.001) and following E-value. …”

Paneth cells are more adherent to laminin than other crypt cells. by Alistair J. Langlands (3164235)

“…Underlying data for panel C can be found in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002491#pbio.1002491.s002" target="_blank">S2 Data</a>, and for panels D and E in <a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.1002491#pbio.1002491.s003" target="_blank">S3 Data</a>.…”

D-loop D674A mutation impairs engineered human TAP1 NBD dimerization and ATPase activity. by Ahmet S. Vakkasoglu (4043111)

“…Significance was evaluated using two-tailed Student’s t-tests, with p < 0.05 indicated by *. …”

Stat3 regulates the transcription of Foxm1. by Guixiang Tan (553792)

“…D3 ES cells were cultured without LIF for 4 days and then LIF was added for 6 h. The mix of two inhibitors (2i) of Mek (PD0325901 1 µM) and GSK3β (CHIR99021 3 µM), or JAK inhibitor I (10 µM) was added 1 hour before the addition of LIF. …”

Data_Sheet_1_A preliminary study for the clinical effect of one combinational physiotherapy and its potential influence on gut microbial composition in children with Tourette syndr... by Chun Bao (384730)

“…</p>Methods<p>The gut microbial profiles were depicted based on the sequence data of 32 patients and 29 matched health children by 16S rDNA amplicon pyrosequencing. Thirty of thirty-two patients underwent uninterrupted two 10-day courses of combinational physiotherapy, which included a 60-minute cranial electrotherapy stimulation (CES) training followed by a 30-minute biofeedback training per session, 2 sessions a day.…”

A Randomized Trial to Assess Anti-HIV Activity in Female Genital Tract Secretions and Soluble Mucosal Immunity Following Application of 1% Tenofovir Gel by Marla J. Keller (118184)

“…Endogenous activity against <em>E. coli</em> and HSV-2 and concentrations of immune mediators were quantified in CVL as candidate biomarkers of safety. …”

<i>Cysltr1</i> gene disruption does not suppress osteoclast formation and bone resorption activity. by Hirofumi Fujita (297325)

“…Representative images are shown. WT, n = 2; KO, n = 2. Scale bars: 100 μm. (B) Osteoclast formation was not affected by <i>Cysltr1</i> gene KO <i>in vitro</i>. …”

Data_Sheet_1_Morpho-Anatomical Traits and Soluble Sugar Concentration Largely Explain the Responses of Three Deciduous Tree Species to Progressive Water Stress.doc by Jonathan O. Hernandez (11801054)

“…Larger vessels (i.e., >100 to ≤ 130) were more frequent at WS for Q. acutissima and B. schmidtii, whereas smaller vessels (i.e., >40 to ≤ 90) were more frequent at WS than at WW for Q. serrata after 8 weeks. …”

Image_1_Early Combination of Albumin With Crystalloid Administration Might Reduce Mortality in Patients With Cardiogenic Shock: An Over 10-Year Intensive Care Survey.tif by Zhi-ye Zou (12651271)

“…Patients who received the albumin combination had decreased 30-day and 60-day mortality (21.7 vs. 32.4% and 25.2 vs. 34.2%, respectively, P < 0.001), and the results were robust after PSM (21.3 vs. 44.7% and 24.9 vs. 47.0%, respectively, P < 0.001) and following E-value. …”

Data_Sheet_1_Morpho-Anatomical Traits and Soluble Sugar Concentration Largely Explain the Responses of Three Deciduous Tree Species to Progressive Water Stress.doc by Jonathan O. Hernandez (11801054)

“…Larger vessels (i.e., >100 to ≤ 130) were more frequent at WS for Q. acutissima and B. schmidtii, whereas smaller vessels (i.e., >40 to ≤ 90) were more frequent at WS than at WW for Q. serrata after 8 weeks. …”

datasheet1_Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury.pdf by Arantza Lamas-Paz (9899561)

“…Increased intestinal permeability, loss of zonula occludens-1 (ZO-1) and MUCIN-2 expression, and alterations in microbiota—increased Lactobacillus and decreased Lachnospiraceae species—were found in the large intestine of mice exposed to EtOH. …”

Inverse agonist of ERRγ inhibits ACEA-mediated fibrinogen gene expression in Huh7 cells. by Yaochen Zhang (4282165)

“…Huh7 and HepG2 cells were treated with ACEA (10 μM) for 12 h. …”

Scavenging of reactive oxygen species by astaxanthin inhibits epithelial–mesenchymal transition in high glucose-stimulated mesothelial cells by Kazuaki Hara (4445914)

“…The NF-κB pathway was activated in response to high glucose concentrations, whereas <i>de novo</i> α-SMA expression was observed with decreased E-cadherin expression. AST treatment attenuated ROS production, inflammatory cytokine production, NF-κB activation, and EMT.…”

Image_3_Early Combination of Albumin With Crystalloid Administration Might Reduce Mortality in Patients With Cardiogenic Shock: An Over 10-Year Intensive Care Survey.tif by Zhi-ye Zou (12651271)

“…Patients who received the albumin combination had decreased 30-day and 60-day mortality (21.7 vs. 32.4% and 25.2 vs. 34.2%, respectively, P < 0.001), and the results were robust after PSM (21.3 vs. 44.7% and 24.9 vs. 47.0%, respectively, P < 0.001) and following E-value. …”

TEMPORAL TREND OF HOSPITALIZATIONS FOR ACUTE BRONCHIOLITIS IN INFANTS UNDER ONE YEAR OF AGE IN BRAZIL BETWEEN 2008 AND 2015 by Kanama Tumba (8045474)

“…The incidence of hospitalization for bronchiolitis increased by 49% over this period (8.5 to 12.7 per 1,000 inhabitants per year). Between 2013 and 2014, the incidence rate of hospitalization for acute bronchiolitis decreased by 8% (12.5 to 11.5 per 1,000 inhabitants per year). …”

Recovery of Bradyrhizobium cells and effects on the physiological quality of soybean seeds sown in dry soil by Débora Bueno Bernardo Pinto (14516629)

“…In the first experiment, irrigation was applied with 2 h, 1, 4, 11, 18, or 21 days after sowing; in the second experiment, sowing was carried out 2 h, 1, 5, 12, 14, or 20 days before irrigation. Each time represented a treatment in a completely randomized design. …”

Image2_Identification of Immune-Related Genes Associated With Bladder Cancer Based on Immunological Characteristics and Their Correlation With the Prognosis.TIF by Zhen Kang (335450)

“…Combining clinical factors, we established a nomogram. The ROC curve in the external validation group showed that the nomogram had a good predictive ability for the survival rate, with a high accuracy, and the AUC values of 1-, 3-, and 5-year survival were 0.744, 0.770, and 0.782, respectively. …”

DataSheet1_Identification of Immune-Related Genes Associated With Bladder Cancer Based on Immunological Characteristics and Their Correlation With the Prognosis.ZIP by Zhen Kang (335450)

“…Combining clinical factors, we established a nomogram. The ROC curve in the external validation group showed that the nomogram had a good predictive ability for the survival rate, with a high accuracy, and the AUC values of 1-, 3-, and 5-year survival were 0.744, 0.770, and 0.782, respectively. …”