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Decreased function of Nrf2 in the aging heart.
Published 2013“…<p>(<b>A</b>) <b>Decreased nuclear translocation of Nrf2 is evident in the heart of aging mice.…”
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Dexamethasone decreases CRTC1 and CRTC2 nuclear localization.
Published 2016“…Dex increased (D) nuclear SIK1 protein (p = 0.005) with no detectable difference in cytosolic protein. n = 3-7/treatment from 3–5 experiments. (E) Representative western blots for cytosolic and nuclear CRTC1, CRTC2, SIK, and CnA proteins are shown; controls for the nuclear (Histone) and cytosolic (GAPDH) fractions are also shown. …”
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Data Sheet 1_Circulating prostaglandin E2 concentrations decrease at birth in premature lambs.docx
Published 2025“…Rationale<p>During pregnancy, prostaglandin E<sub>2</sub> (PGE<sub>2</sub>) is released from the placenta and circulates in relatively high concentrations in the fetus. …”
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Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis.
Published 2011“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log<sub>2</sub>-transformed fold-change less than -0.50). …”
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mGluR5 receptor decreased glycinergic currents.
Published 2019“…<p>(<b>A–B</b>) Bath perfusion of DHPG for 3 min reduced GlyR-IPSCs (<b>A</b>; 70.2 ± 4.2% of baseline at 15–20 min post-DHPG, <i>t</i>[16] = 6.707, <i>p</i> < 0.001, paired Student <i>t</i> test), but not GABA<sub>A</sub>-receptor–mediated IPSCs (<b>B</b>; 102.9 ± 3.3% of baseline at 15–20 min post-DHPG, <i>t</i>[5] = 0.347, <i>p</i> = 0.743) in spinal slices of mice. …”
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The Hh signaling pathway effectors are decreased in E14.5 <i>Fuz<sup>−/−</sup></i> mouse embryos.
Published 2013“…<p><b>A</b>) Immunofluorescence of Patched1 in sagittal sections of E14.5 <i>Fuz<sup>+/−</sup></i> heterozygous embryos. …”
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