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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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ALVAC-HIV elicits V2, V3, and CD4 inducible (CD4i) binding antibody responses.
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RDV mixed array inhibitor screen with SARS-CoV-2<sub>Engl2</sub> in VeroE6 cells.
Published 2021Subjects: -
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Supplementary Figure 2 from Decreased eIF3e Expression Can Mediate Epithelial-to-Mesenchymal Transition through Activation of the TGFβ Signaling Pathway
Published 2023“…<p>Supplementary Figure 2- Phosphorylation of eIF4E is decreased in A549 and MCF-10A cells that have decreased eIF3e expression. …”
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Supplementary Material for: Blood Outgrowth Endothelial Cells Reduce Hypoxia-Mediated Fibroblast to Myofibroblast Conversion by Decreasing Proangiogenic Cytokines
Published 2017“…This is associated with a decrease in several proangiogenic genes including vascular endothelial growth factor A, platelet-derived growth factor, fibroblast growth factor and matrix metalloproteinase 2 in fibroblasts in contact with BOEC when compared to fibroblasts alone. …”
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Frictional Effects on RNA Folding: Speed Limit and Kramers Turnover
Published 2018“…In the high-friction regime (η ≳ 10<sup>–5</sup> Pa·s), for both HP and PK, <i>k</i><sub>F</sub> values decrease as 1/η, whereas in the low friction regime, <i>k</i><sub>F</sub> values increase as η increases, leading to a maximum folding rate at a moderate viscosity (∼10<sup>–6</sup> Pa·s), which is the Kramers turnover. …”