CAK inhibition decreases gene transcription after UV-induced DNA damage. by Hany H. Arab (364331)

<i>Prep1</i>^-/- ES cells express decreased levels of Pbx1 and Pbx2 proteins but not of their RNA. by Audrey Laurent (129711)

C2GnT1 gene knock-down results in decreased binding of cells to E-selectin. by Catherine A. St. Hill (357388)

“…At a shear stress of 0.5 dynes/cm², significantly fewer C2GnT1 shRNA transduced cells accumulated on E-selectin than un-manipulated LS174T cells, *p = 0.04. …”

SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

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Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

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Expression of a 65kDa isoform of eIF2Bε leads to a global decrease in protein synthesis. by Lauren K. Brady (4479244)

eIF5a interacts with Mfn1 and preserves mitochondrial integrity. by Dong Ma (584680)

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Effect of eIF5a and Mfn1 expression on mitochondrial morphology. by Dong Ma (584680)

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eIF5a affects the expression of mitochondrial dynamics–related genes. by Dong Ma (584680)

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Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

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Fe limitation decreases transcriptional regulation over the diel cycle in the model diatom <i>Thalassiosira pseudonana</i> - Fig 2 by Johanna A. L. Goldman (7372724)

Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability. by Yuguo Yu (172221)

“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”

Bioluminescence decreases with aging in transgenic mice. by Sarah E. Mailhiot (766685)

Decreased <i>Pax2</i> expression in <i>p53^−/−</i> embryonic kidneys. by Zubaida Saifudeen (135684)

“…<b>B</b>) In situ hybridization. Decreased expression of <i>Pax2</i> mRNA at E12.5. …”

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

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Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter. by Dong Ma (584680)

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2-ME decreases blood pressure in Sprague Dawley rats. by Weiyu Chen (2216251)

The prolyl 4-hydroxylase inhibitor GSK360A decreases post-stroke brain injury and sensory, motor, and cognitive behavioral deficits - Fig 4 by Jin Zhou (90734)

Raw data used to generate the graphs shown in Figs 1B, 1E, 2B, 3B, 4B and 5A–5C of representative experiments from three independent biological repeats. by Timilehin Faboro (20175963)

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