MJ-29 decreases the viability and induces apoptotic death in WEHI-3 cells. by Chi-Cheng Lu (163756)

Virus from obese mice decreased infectivity to mosquitoes and lower transmission rates. by James Weger-Lucarelli (603766)

<i>Prep1</i>^-/- ES cells express decreased levels of Pbx1 and Pbx2 proteins but not of their RNA. by Audrey Laurent (129711)

C2GnT1 gene knock-down results in decreased binding of cells to E-selectin. by Catherine A. St. Hill (357388)

“…At a shear stress of 0.5 dynes/cm², significantly fewer C2GnT1 shRNA transduced cells accumulated on E-selectin than un-manipulated LS174T cells, *p = 0.04. …”

SMC-specific knockout of Klf5 (smcKlf5^−/−) exacerbates the progression of Ang II–induced AAA by facilitating ROS formation. by Dong Ma (584680)

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Young (3 months) or old (18 months) WT and smcKlf5^−/− mice were infused with Ang II for 28 days. by Dong Ma (584680)

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Mst1^−/− mice exhibit decreased incidence and severity of CIA. by Konstantin V. Salojin (567844)

PIN1 silencing leads to decreases in the protein levels of HIF-1α. by Hyeong-jun Han (846566)

“…E) ATRA decreases the expression of HIF-1α and PIN1 in HCT116/5xHRE-ODD-luc cells in dose-dependent manner. …”

Expression of a 65kDa isoform of eIF2Bε leads to a global decrease in protein synthesis. by Lauren K. Brady (4479244)

eIF5a interacts with Mfn1 and preserves mitochondrial integrity. by Dong Ma (584680)

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Effect of eIF5a and Mfn1 expression on mitochondrial morphology. by Dong Ma (584680)

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eIF5a affects the expression of mitochondrial dynamics–related genes. by Dong Ma (584680)

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Cardiac function assessed by echocardiography in Ang II–infused young (3 months) or old (18 months) WT and smcKlf5^−/− mice. by Dong Ma (584680)

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Increasing temperature decreases oxygen concentration and decreasing oxygen content decreases neuronal excitability. by Yuguo Yu (172221)

“…Increasing temperature can dramatically decrease oxygen levels. B. Response of layer 2/3 pyramidal cells (n = 5) to the intracellular injection of a depolarizing current pulse (200 pA, 500 ms) at different temperatures (same experiments as in A). …”

Bioluminescence decreases with aging in transgenic mice. by Sarah E. Mailhiot (766685)

Decreased <i>Pax2</i> expression in <i>p53^−/−</i> embryonic kidneys. by Zubaida Saifudeen (135684)

“…<b>B</b>) In situ hybridization. Decreased expression of <i>Pax2</i> mRNA at E12.5. …”

Representative TUNEL- and DAPI-stained sections from the abdominal aortas of young and old WT and smcKlf5^−/− mice following 28 days of Ang II infusion. by Dong Ma (584680)

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Klf5 activates the transcription of the eIF5a gene through direct binding to its promoter. by Dong Ma (584680)

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NatB inactivation decreased the level of MAPK and proposed model of EGFR/MAPK signaling regulation by NatB and the N-end rule pathways. by Zhentao Sheng (107495)

“…Drk/Grb2 and MAPK, two positive components of the EGFR signaling pathway are targeted for degradation by the Arg/N-end rule pathway and E3 ubiquitin ligase Ubr4 while PP2AC, a negative regulator of EGFR signaling pathway, is targeted for degradation by the Ac/N-end rule pathway E3 ubiquitin ligase Cnot4. …”

A genetic variant in human FIRE is associated with a decreased interferon response in myeloid cells. by Anaïs Assouvie (9600529)