S554fs-ERα suppresses oncogenic properties of CarB-transfected cells and alters cytoskeletal and cell adhesion molecules’ levels. by Stella Logotheti (312707)

“…Colonies were scored after 3 to 4 weeks. CarB-V is compared against CarB, C-ER3, C-ER4 and C-ER7 using t-test, and results are flagged with no asterisk when P-value is more than 0.05, with a single asterisk when the P-value is less than 0.05, with two asterisks when the P-value is less than 0.01, and three asterisks when the P-value is less than 0.001.…”

Lectin-like oxidised LDL (LOX-1) receptor expression in thoracic aorta. by Lesley Brennan (3132840)

“…Representative blots from a single gel are shown, n = 3–5/group.</p>…”

Genetic Variants in the p14ARF/MDM2/TP53 Pathway Are Associated with the Prognosis of Esophageal Squamous Cell Carcinoma Patients Treated with Radical Resection by Jing Li (10611)

“…According to multivariate Cox hazard analysis and multiple testing, the TC/CC genotype of <i>p14ARF</i> rs3814960 was shown to be strongly related to a decreased overall survival (OS) (HR = 2.77, 95% CI: 1.33–5.75, <i>P</i> = 0.006, <i>Pc</i> = 0.030) and disease-free survival (DFS) (HR = 2.45, 95% CI: 1.30–4.61, <i>P</i> = 0.005, <i>Pc</i> = 0.025). …”

Data_Sheet_1_The efficacy and safety of Chinese herbal medicine as an add-on therapy for amyotrophic lateral sclerosis: An updated systematic review and meta-analysis of randomized... by Yingdi Liao (13918467)

“…The methodological quality of the included trials was assessed using the Cochrane risk of bias tool, and a pooled data analysis was performed using RevMan 5.3.…”

Animal study showed that cerulenin combined with rapamycin could mediate synergistic anti-tumor effect in mice incubated with MCF-7/HER2 breast cancer cells. by Chen Yan (478322)

“…Compared with baseline, the body weight of the mice increased by 36.5% in the combination group and by 8.2% in the cerulenin-only group, whereas the body weight decreased by 27.5% and 13.6% in the negative control and rapamycin-only groups, respectively.…”

The effect of PINK1 deficiency on mitochondrial membrane potential. by Hilary K. Siddall (407990)

“…<p>Mitochondrial resting membrane potential measured by TMRM fluorescence (in arbitrary units A.U.) in PINK1+/+ and PINK1−/− adult cardiomyocytes, demonstrating a lower mitochondrial membrane potential (decreased TMRM fluorescence) in PINK1−/− cardiomyocytes. …”

ATRA increased the number of ciliated cells in HT and LT. by Carmen Retana (479628)

“…In control, ATRA decreased the number of ciliated cells. Panel k shows the zoom of a cell with two cilia. …”

Data Sheet 1_Latencies of conditioned vocal responses to hearing test tones in killer whales (Orcinus orca).pdf by Jared Stephens (209848)

“…</p>Methods<p>In this study, behavioral hearing tests conducted with two killer whales were analyzed to capture conditioned vocal response latency, which is the time between the onset of the acoustic signal and the onset of the response (i.e., reaction time).…”

DataSheet1_Evaluation of the efficacy of Abelmoschus manihot (L.) on diabetic nephropathy by analyzing biomarkers in the glomeruli and proximal and distal convoluted tubules of the... by Hongmei Yu (584700)

“…</p><p>Result and discussion: After HK capsule treatment for 4 weeks, the urinary albumin-to-creatinine ratio in db/db mice was found to be significantly decreased. The activities of col4a3, slc5a2, slc34a1, slc12a3, and slc4a1 in the kidneys were upregulated in db/db mice prior to the treatment but downregulated after HK capsule treatment. …”

Table1_Small-molecule BCL6 inhibitor protects chronic cardiac transplant rejection and inhibits T follicular helper cell expansion and humoral response.DOCX by Yuxuan Xia (14800378)

“…Splenocytes were collected at different time points after transplantation for CXCR5⁺PD-1⁺ and CXCR5⁺BCL6⁺ Tfh cells detection by flow cytometry (FCM). …”

Cellular functions misregulated by HDACi after 48 h schistosomula treatment. by Letícia Anderson (2543926)

“…<p>IPA analysis pointed to the “cell movement of smooth muscle cells” cellular function (A) that could be functionally limited due to the down-regulated transcription of all involved genes. …”

Identifying the groups becomes harder when the degradation chain is long, especially for groups catalyzing upstream reactions. by Yuanchen Zhao (12905580)

“…As the number of groups <i>k</i> in the output increases, the algorithm first finds group 3 (direct producers), then group 2 and group 1, with ever-decreasing recovery quality. (B) The recovery quality of Metropolis of the most upstream group (group 1, blue dashed line) and the direct producers (group <i>N</i> − 1, red solid line) in the <i>N</i>-metabolites degradation chain, shown as a function of <i>N</i>. …”

Effect of deferiprone on cell cytotoxicity. by Chhanda Bose (787135)

“…</b> Deferiprone treatment decreases the release of catalytic iron of Omniscan-treated human PBMC, as shown by use of a bleomycin-detectable iron assay. …”

Diagrams for measuring basilar membrane vibrations. by Tianying Ren (328287)

“…<p>(A) Two measured locations on the BM and one on the stapes (red dots). …”

Table_1_Effects of assisted reproductive technology on gene expression in heart and spleen tissues of adult offspring mouse.xlsx by Huanhuan Chen (706338)

“…STRING analysis identified Ccl2, Ptgs2, Rock1, Mapk14, Agt, and Wnt5a as the core interacting factors. DEGs in the spleen are significantly enriched in anti-infection and immune responses, which include the core factors Fos, Jun and Il1r2. …”

Paclitaxel inhibits proliferation, induces EMT, and up-regulates miR-375 expression simultaneously in cervical cancer cells. by Yuanming Shen (645855)

“…The representative cells with morphological changes were labeled (<b>b</b>) Immunoblotting measured the expression of Ecadherin and other EMT related proteins (vimentin, Ncadherin, and fibronectin) in cervical cancer cells (SiHa and CaSki) under different amounts (0, 5, 10, 20 nM) of paclitaxel treatment. The expression of Ecadherin protein was decreased and the expressions of vimentin, Ncadherin, and fibronectin protein were increased in cells treated with paclitaxel for 72 hours in a dose-responsive manner. …”

Table_3_Effects of assisted reproductive technology on gene expression in heart and spleen tissues of adult offspring mouse.docx by Huanhuan Chen (706338)

“…STRING analysis identified Ccl2, Ptgs2, Rock1, Mapk14, Agt, and Wnt5a as the core interacting factors. DEGs in the spleen are significantly enriched in anti-infection and immune responses, which include the core factors Fos, Jun and Il1r2. …”

Hydrogen sulfide in posthemorrhagic shock mesenteric lymph drainage alleviates kidney injury in rats by B. Han (2963265)

“…We investigated the role of hydrogen sulfide (H2S) in PHSML drainage in alleviating acute kidney injury (AKI) by administering D,L-propargylglycine (PPG) and sodium hydrosulfide hydrate (NaHS) to 12 specific pathogen-free male Wistar rats with PHSML drainage. A hemorrhagic shock model was established in 4 experimental groups: shock, shock+drainage, shock+drainage+PPG (45 mg/kg, 0.5 h prehemorrhage), and shock+drainage+NaHS (28 µmol/kg, 0.5 h prehemorrhage). …”

Table_2_Effects of assisted reproductive technology on gene expression in heart and spleen tissues of adult offspring mouse.docx by Huanhuan Chen (706338)

“…STRING analysis identified Ccl2, Ptgs2, Rock1, Mapk14, Agt, and Wnt5a as the core interacting factors. DEGs in the spleen are significantly enriched in anti-infection and immune responses, which include the core factors Fos, Jun and Il1r2. …”

Table_11_Neutrophil extracellular traps promote bronchopulmonary dysplasia-like injury in neonatal mice via the WNT/β-catenin pathway.xls by Liujuan Sun (15364594)

“…We found that the expression of the target genes c-MYC, cyclin D, and vascular endothelial growth factor (VEGF) and the important proteins WNT3a and β-catenin significantly decreased. Moreover, heparin, which is a NET inhibitor, attenuated changes in gene and protein expression, thereby attenuating BPD-like changes.…”