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101681
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101682
Effect of miR-21 expression on cell proliferation of ARPE-19 cells.
Published 2016“…Expression level of miR-21 in miR-21 inhibitor-transfected ARPE-19 cells in the presence or absence of TGF-β2 was calculated by comparing with negative control inhibitor-transfected cells (B). …”
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101683
Image 3_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.jpeg
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101684
Table1_From vision toward best practices: Evaluating in vitro transcriptomic points of departure for application in risk assessment using a uniform workflow.docx
Published 2023“…An assessment of multiple data points for single chemicals revealed that longer exposure duration and varied cell culture systems (e.g., 3D vs. 2D) lead to a decreased tPOD value that indicated increased chemical potency. …”
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101685
Image 4_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.jpeg
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101686
Table_1_Mapping the Tooth Enamel Proteome and Amelogenin Phosphorylation Onto Mineralizing Porcine Tooth Crowns.xlsx
Published 2019“…We report higher protein diversity than previously published and Gene Ontology (GO)-defined protein functions related to the regulation of mineral formation in secretory enamel (e.g., casein α-S1, CSN1S1), immune response in erupted enamel (e.g., peptidoglycan recognition protein, PGRP), and phosphorylation. …”
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101687
Analysis of TMD-effector translocation in mutants of the T4CC.
Published 2024“…The measurement was performed 4 h post infection by the split NanoLuc-based translocation assay shown in <a href="http://www.plospathogens.org/article/info:doi/10.1371/journal.ppat.1012118#ppat.1012118.g002" target="_blank">Fig 2E</a>. The data points represent the mean (± standard deviation) of at least three independent experiments. …”
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101688
DataSheet1_Pioglitazone treatment mitigates cardiovascular bioprosthetic degeneration in a chronic kidney disease model.PDF
Published 2024“…Aims<p>Chronic kidney disease (CKD) is a risk factor for the development of cardiovascular diseases, e.g., atherosclerosis and calcific aortic valve disease, leading inevitably to valve replacement surgery. …”
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101689
β-Catenin Acts to Regulate Bone Formation in Mice Expressing Osteoblast-Specific β-Catenin Null or Stabilized Alleles
Published 2007“…</p> <p>(B) Histomorphometric analysis of calluses at 1 wk following fracture, as indicated by cartilage volume (CV) as a percentage of total callus tissue volume (TV).</p> <p>(C–E) Radiographic analysis from <i>α1(I)-Catnb<sup>null</sup></i> mice (C), from <i>α1(I)-Catnb<sup>stab</sup></i> mice (D), and from wild-type littermate mice (E) at 3 wk after fracture. …”
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101690
Data_Sheet_1_Mapping the Tooth Enamel Proteome and Amelogenin Phosphorylation Onto Mineralizing Porcine Tooth Crowns.PDF
Published 2019“…We report higher protein diversity than previously published and Gene Ontology (GO)-defined protein functions related to the regulation of mineral formation in secretory enamel (e.g., casein α-S1, CSN1S1), immune response in erupted enamel (e.g., peptidoglycan recognition protein, PGRP), and phosphorylation. …”
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101691
Outline of results for spine maturation.
Published 2017“…For these plots we used <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170113#pone.0170113.e029" target="_blank">Eq 2</a> with . Experimental data from [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0170113#pone.0170113.ref013" target="_blank">13</a>] is highlighted in gray. …”
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101692
Table 3_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.xlsx
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101693
SCD1 activity is required for adipocytes to increase maximal OCR and spare respiratory capacity during adaptation to cool temperature.
Published 2021“…<p>(<b>A</b>) CAY10566 decreases TAG containing monounsaturated lipids (left panels) and increases TAG containing saturated lipids (right panels). …”
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101694
Sensitivity analysis to determine the effect of varying inhibitor adhesion kinetics upon treatment efficacy.
Published 2018“…Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006071#pcbi.1006071.e002" target="_blank">1</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006071#pcbi.1006071.e016" target="_blank">8</a> were solved using ode15s. inhibitors cm<sup>−3</sup> (the standard value). …”
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101695
Table 1_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.xlsx
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101696
Supplementary Material for: Demineralization Inhibitory Effects of Highly Concentrated Fluoride Dentifrice and Fluoride Gels/Solutions on Sound Dentin and Artificial Dentin Caries...
Published 2020“…Furthermore, half of the specimens in each group were brushed (10 s; twice per day) with dentifrice slurries containing either 1,450 ppm (e.g., AmF<sub>1450</sub>) or 5,000 ppm (e.g., AmF<sub>5000</sub>). …”
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101697
Image 1_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.jpeg
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101698
Table 4_Endolysin significantly improves symptoms with atopic dermatitis: bridging the gap from research to clinical practice.xlsx
Published 2025“…An open-label, single-center, investigator-initiated clinical study (ChiCTR25001192) was conducted in which participants, who received the endolysin gel twice daily, underwent follow-up assessments at baseline, treatment weeks 1 and 2, with an optional extension up to 3 months.</p>Results<p>Statistically significant reductions in skin lesion scores, S. aureus load, and AD-related immune mediators (i.e., IgE, TSLP, IL-33) were observed in the Staphyrase<sup>®</sup> group relative to the model group. …”
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101699
Image_8_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”
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101700
Image_1_Pharmacokinetic Behavior of Vincristine and Safety Following Intravenous Administration of Vincristine Sulfate Liposome Injection in Chinese Patients With Malignant Lymphom...
Published 2018“…</p><p>Results: In this phase Ia study, a total of eight subjects participated. VCR elimination from the circulation after injection of VSLI was characterized by a significantly increased maximum concentration (C<sub>max</sub>, 86.6 ng/mL) and plasma area under the plasma concentration-time curve from zero to infinity (AUC<sub>0-Inf</sub>, 222.1 ng/mL h), markedly decreased distribution volume (V<sub>z</sub>, 224.1 L) and plasma clearance (CL, 8.9 L/h) compared to lower C<sub>max</sub> (26.6 ng/mL) and AUC<sub>0-Inf</sub> (95.1 ng/mL h), larger V<sub>z</sub> (688.8 L) and CL (22.1 L/h) for VSI. …”