MeHg Suppresses PDGF-Mediated Signaling from the Nucleus Back to the Receptor by Zaibo Li (273729)

“…</p> <p>(D) Cells grown as in (A) showed lower levels of Akt (Thr 308) phosphorylation.</p> <p>(E) Cells grown as in (A) also showed decreased phosphorylation of PDGFRα (as detected with anti-PDGFRα(pY⁷⁴²) antibody). …”

A 21-year-old man with osteosarcoma of the left femur. by Min Wook Joo (3746446)

“…(C) A T2-weighted coronal MRI scan image taken after preoperative chemotherapy showing increased intra-tumoral ossification and decreased extraosseous tumor extension with better-defined margins compared to the initial image. …”

Histological analysis of the calluses. by Tero Puolakkainen (4247116)

“…At the four-week time point ActRIIB-Fc treatment greatly enhanced (H) bone volume/tissue volume and (J) trabecular numbers and decreased their (I) separation * = p<0.05 ** = p<0.01, *** = p<0.001. n = 6 for PBS 2 weeks, 6 for ActRIIB-Fc 2 weeks, 7 for PBS 4 weeks and 7 for ActRIIB-Fc 4 weeks.…”

Effect of the helical parameters. by Young-Joo Kim (1955062)

“…<p>Results are calculated using E_c = 668 MPa, D = 2.4 nm, 1/AR = 0.6, S_r = 1100 pN and Ф = 130°. …”

Permanent effects of neonatal novelty exposure on social competitive success and stress response system function (24 months of age). by Katherine G. Akers (377156)

“…Novel but not Home rats exhibited a significant reduction in wins from Day 1 to Day 2. E. Despite a significant difference between Novel and Home rats in wins on Day 1, there was no parallel difference in post-competition corticosterone (CORT) concentration. …”

Relative mRNA abundance of nine target genes after injecting siRNAs. by Hang Li (123039)

“…Larvae injected with siRNA with a random sequence were used as negative controls. Two housekeeping genes, G3PDH and E2F, were used as multiple internal controls. …”

Post-harvest quality of papaya coated with polivinilic alcohol and maize starch by Mariana Teixeira Pigozzi (10398791)

Secretion of soluble factors by MSCs grown in plate or collagen scaffold. by Iran Rashedi (4557406)

“…The basal level of prostaglandin (PG) E2 was slightly, but significantly, higher in patch-MSC cultures. …”

List of confirmed hit compounds. by Domokos Gerö (422086)

“…(Abbreviations: Bay 11-7085: (2<i>E</i>)-3-[[4-(1,1-dimethylethyl)phenyl]sulfonyl]-2-propenenitrile, MNS: 3,4-methylenedioxy-β-nitrostyrene, PABA potassium salt: para-aminobenzoic acid potassium salt, NF-κB: nuclear factor κB, HIV: human immunodeficiency virus, Src: sarcoma tyrosine kinase, Syk: Spleen tyrosine kinase).…”

Reduced sCLU membrane levels in hemolytic anemia correlate to markers of RBCs senescence, redox imbalance and erythrophagocytosis. by Marianna H. Antonelou (342494)

Absence of excision repair of CPDs in telomeres. by Patrick J. Rochette (249729)

Table 4_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 3, AKI patients exhibited further distinct changes in NK cells and T cell activation/exhaustion markers. A predictive model incorporating key clinical (APACHE II and creatinine) and lymphocyte subsets (CD15⁺T%_1^st, CD4⁺LAG3⁺T%_1^st, Th17_1^st, CD8⁺PD1⁺T%_3^rd, CD8⁺TIGIT⁺T%_3^rd, E_MDSC_3^rd, CD8⁺CCR7⁺CD45RA⁺T%_3^rd, CD4⁺CTLA4⁺T%_3^rd, CD4⁺TIM3⁺T%_3^rd, PMN_MDSC_3^rd, and M_MDSC_3^rd) achieved high accuracy, with an AUC of 0.989 in the training set, 0.895 in the validation set, and 0.906 in the test set. …”

Table 6_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 3, AKI patients exhibited further distinct changes in NK cells and T cell activation/exhaustion markers. A predictive model incorporating key clinical (APACHE II and creatinine) and lymphocyte subsets (CD15⁺T%_1^st, CD4⁺LAG3⁺T%_1^st, Th17_1^st, CD8⁺PD1⁺T%_3^rd, CD8⁺TIGIT⁺T%_3^rd, E_MDSC_3^rd, CD8⁺CCR7⁺CD45RA⁺T%_3^rd, CD4⁺CTLA4⁺T%_3^rd, CD4⁺TIM3⁺T%_3^rd, PMN_MDSC_3^rd, and M_MDSC_3^rd) achieved high accuracy, with an AUC of 0.989 in the training set, 0.895 in the validation set, and 0.906 in the test set. …”

Table 1_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 3, AKI patients exhibited further distinct changes in NK cells and T cell activation/exhaustion markers. A predictive model incorporating key clinical (APACHE II and creatinine) and lymphocyte subsets (CD15⁺T%_1^st, CD4⁺LAG3⁺T%_1^st, Th17_1^st, CD8⁺PD1⁺T%_3^rd, CD8⁺TIGIT⁺T%_3^rd, E_MDSC_3^rd, CD8⁺CCR7⁺CD45RA⁺T%_3^rd, CD4⁺CTLA4⁺T%_3^rd, CD4⁺TIM3⁺T%_3^rd, PMN_MDSC_3^rd, and M_MDSC_3^rd) achieved high accuracy, with an AUC of 0.989 in the training set, 0.895 in the validation set, and 0.906 in the test set. …”

Table 3_Establishment and validation of the prediction model based on lymphocyte subsets for acute kidney injury in sepsis patients.docx by Leyi Wang (408009)

“…On day 3, AKI patients exhibited further distinct changes in NK cells and T cell activation/exhaustion markers. A predictive model incorporating key clinical (APACHE II and creatinine) and lymphocyte subsets (CD15⁺T%_1^st, CD4⁺LAG3⁺T%_1^st, Th17_1^st, CD8⁺PD1⁺T%_3^rd, CD8⁺TIGIT⁺T%_3^rd, E_MDSC_3^rd, CD8⁺CCR7⁺CD45RA⁺T%_3^rd, CD4⁺CTLA4⁺T%_3^rd, CD4⁺TIM3⁺T%_3^rd, PMN_MDSC_3^rd, and M_MDSC_3^rd) achieved high accuracy, with an AUC of 0.989 in the training set, 0.895 in the validation set, and 0.906 in the test set. …”

Numerical integration of the rate equations of the MerB reaction mechanism by Pedro Silva (532059)

“…</p> <p> </p> <p>Syntax is:</p> <p> </p> <p>HgMerB_kinetics [initial concentration of organomercurial (optional)] [number of steps with timestep tightening] [initial_timestep][pH] [type of molecule] [how many seconds of kinetic information you want] [HgMerB (or free MerB) concentration] [concentration of the Hg-removing molecules tested] [barriers in kcal.mol-1 for the 38 reaction steps] [name of output file]</p> <p> </p> <p>Type of molecule is : 1 for MerA, 2 for dithiothreitol, 3 for GSH or other monothiols</p> <p>Notes on the algorithm:</p> <p> </p> <p>A) concentrations are output whenever :</p> <p>A1) concentration of HgMerB decreases by 1%, or</p> <p>A2) concentration of product increases by 1% of initial MerB concentration, or</p> <p>A3) 10^7 integration timesteps have elapsed since the last output (or 3*10^5, if less than 10^7 integration timestpes have elapsed since the beginning of the simulation)</p> <p> </p> <p>B) Integration timestep is scaled to ensure that the concentration of every intermediate does not increase more than 10% of its previous concentration. …”

Ultrasensitive Detection of Dopamine with Carbon Nanopipets by Keke Hu (1414000)

“…Recent attempts to determine neurotransmitters in single cells and vesicles have provided additional impetus for decreasing the probe dimensions. Here, we report two types of dopamine sensors based on carbon nanopipets (CNP) prepared by chemical vapor deposition of carbon into prepulled quartz capillaries. …”

Ultrasensitive Detection of Dopamine with Carbon Nanopipets by Keke Hu (1414000)

“…Recent attempts to determine neurotransmitters in single cells and vesicles have provided additional impetus for decreasing the probe dimensions. Here, we report two types of dopamine sensors based on carbon nanopipets (CNP) prepared by chemical vapor deposition of carbon into prepulled quartz capillaries. …”

Effects of TXA on tPA mediated fibrinolysis. by Tie Bo Wu (3417305)

“…<p>Modeling results show that Tranexamic Acid (TXA) affects tPA mediated fibrinolysis in a dose dependent fashion. As the concentration of TXA increases, the rate of fibrinolysis decreases. …”

The minimum ANTAR domain for RNA recognition. by Arati Ramesh (159304)

“…B) A representative EMSA is shown for association of ANTARcc with 5′-radiolabeled RNA (<i>eutP</i> 5′ leader region) on a non-denaturing polyacrylamide gel. …”