Pollen-based Holocene vegetation reconstruction.xlsx by Yuanhao Sun (12697028)

“…In the Daihai basin, the vegetation cover changed relatively little, maintaining values of 45–50%, and only increased during the interval of 8–5.1 ka, when it attained a maximum of 67%. In the Gonghai area, the vegetation cover remained at a higher level at 70–80% for an extended interval, before decreasing substantially to 58% after 1.4 ka. …”

Gene expression profiles in wildtype, <i>Tnfr1</i>- and <i>Tnfr2-</i>deficient glomeruli after TNF stimulation ex vivo. by Anela Taubitz (433585)

“…<p>Expression profiling by microarrays was performed on isolated glomeruli from wildtype, <i>Tnfr1</i>−/− and <i>Tnfr2</i>−/− mice 12 after stimulation with 50 ng/ml TNF for 12 hours ex vivo. A negativ “fold change” (black to green) indicates decreased expression and a postive “fold change” (black to red) indicates increased expression in a glomerular sample compared with the average of all analyzed samples. …”

Changes in Practice Patterns of Clopidogrel in Combination with Proton Pump Inhibitors after an FDA Safety Communication by Annie Guérin (215559)

“…Among combination therapy users, the probability of patients using a combination with a CYP2C19 inhibitor decreased by 53% (OR = 0.47; <i>p</i><0.001); however, 31.5% of patients were still prescribed a clopidogrel-PPI combination therapy. …”

MDS ordinations of modelled reef state showing the interaction between nutrification-sedimentation and fishing. by Georgina G. Gurney (486242)

“…<p>MDS ordinations of modelled reef state showing the nature of the interaction between nutrification-sedimentation (NS) and fishing (F). At Cangaluyan after 5 years (a) variability in reef state increased significantly as the magnitude of F and NS decreased (pairwise <i>p</i><0.0385 all cases). …”

Analysis of the myonuclei and myofibre volume of isolated EDL single fibres. by Alice Neal (321532)

“…Volume increases significantly between 2 weeks and 3 months of age (p<.001), and decreases between 1 year and 2.5 years (p<.001). There is no difference in fibre volume between males and females at any age. …”

Inhibition of TGF-β leads to functional and morphological changes in retinal neural cells. by Tony E. Walshe (269700)

“…(B) Inhibition of TGF-β did not alter the a-wave response, however b-wave was significantly decreased in Ad-sEng mice (n = 5, * p<0.05). …”

Internal Ribosomal Entry Site-Mediated Translation Is Important for Rhythmic PERIOD1 Expression by Kyung-Ha Lee (161966)

“…Translation of m<em>Per1</em> is directed by both a cap-dependent process and cap-independent translation mediated by an internal ribosomal entry site (IRES) in the 5′ untranslated region (UTR). …”

p150 catalyzes microtubules nucleation. by Jacob E. Lazarus (433707)

“…(D) Montage from TIRF nucleation assay shows that dimeric p150 Nt-GCN4 catalyzes microtubule nucleation in contrast to monomeric p150 Nt. Scale bar, 12.5 µm. (E) Montage of representative microtubules nucleated in the presence of a low concentration of p150 dimer. …”

Data_Sheet_2_Transcriptome Analysis Reveals That Naphthenic Acids Perturb Gene Networks Related to Metabolic Processes, Membrane Integrity, and Gut Function in Silurana (Xenopus) t... by Juan Manuel Gutierrez-Villagomez (7320332)

“…In S. tropicalis embryos exposed to the AEOs, the mRNA levels of eprs (bifunctional glutamate/proline-tRNA ligase) and slcs5a1 (sodium/glucose cotransporter 1) were significantly decreased compared to the controls. …”

Data Sheet 1_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”

Data_Sheet_1_The Crocus sativus Compounds trans-Crocin 4 and trans-Crocetin Modulate the Amyloidogenic Pathway and Tau Misprocessing in Alzheimer Disease Neuronal Cell Culture Mode... by Ioanna Chalatsa (6505079)

“…Trans-crocin 4 significantly decreased of β-secretase, a key enzyme of the amyloidogenic pathway, and APP-C99, while it decreased γ-secretases that generate toxic beta-amyloid peptides. …”

Data Sheet 3_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”

Data Sheet 2_How low can you go? Antibiotic use in Swedish dogs with gastroenteritis.pdf by Ditte Ljungquist (20446670)

“…Concurrently, the annual all-cause mortality decreased for all CGE consultations. Higher levels of antibiotic use were seen in hospitalized CGE (21.7% compared to 2.1% for non-hospitalized CGE, OR 13.1, 95% CI: 12.3–14.0, p < 0.001) and hemorrhagic diarrhetic CGE (21.0% compared to 5.5% for non-hemorrhagic diarrhetic CGE, OR 4.6, 95% CI: 4.2–4.9, p < 0.001).…”

Data_Sheet_1_Transcriptome Analysis Reveals That Naphthenic Acids Perturb Gene Networks Related to Metabolic Processes, Membrane Integrity, and Gut Function in Silurana (Xenopus) t... by Juan Manuel Gutierrez-Villagomez (7320332)

“…In S. tropicalis embryos exposed to the AEOs, the mRNA levels of eprs (bifunctional glutamate/proline-tRNA ligase) and slcs5a1 (sodium/glucose cotransporter 1) were significantly decreased compared to the controls. …”

Table_1_Transcriptomic and phenotype analysis revealed the role of rpoS in stress resistance and virulence of pathogenic Enterobacter cloacae from Macrobrachium rosenbergii.DOCX by Xiaojian Gao (9166612)

“…The phenotype changes also showed the E. cloacae-rpoS RNAi strain exhibited significantly decreasing abilities of survival in environmental stresses (starvation, salinity, low pH, and oxidative stress), biofilm production, movement, adhesion to cells, pathogenicity, and colonization to M. rosenbergii. …”

Growth rate controls mRNA turnover in steady and non-steady states by José García-Martínez (41415)

A Model for the Control of NEB by Mtrm-Induced Inhibition of Polo by Youbin Xiang (32328)

Effects of neutralizing TLR4 antibody compared to goat IgG control antibody on TLR4-induced gene transcription and cytokine activation. by Kok-Hooi Yew (139311)

“…B–F: Similar results were obtained for MD2 (B), TIRAP (C), IL-6 (E) and IL-8 (F). However, no effect on TRAM (D) was seen. …”

Simplified scheme of F-induced alterations in the expression of proteins related to energetic metabolism pathways in liver. by Heloísa Aparecida Barbosa da Silva Pereira (459610)

“…<p>F^- (fluoride ion); red arrows indicate increased expression and green arrows indicate decreased expression; P (phosphate); Fructose-bisP-AldoB (Fructose-bisphosphate aldolase B); L-PK (R-type isoform of piruvate kinase isozymes R/L); PDHE1-B (Pyruvate dehydrogenase E1 component subunit beta, mitochondrial); LDH-A (L-lactate dehydrogenase A chain); Mdh2 (Malate dehydrogenase); OAA (oxaloacetate); VLCAD (Very long-chain specific acyl-CoA dehydrogenase, mitochondrial); 3-Ketoacyl-CoA thiolase – m.(3-Ketoacyl-CoA thiolase, mitochondrial). …”

Overexpression of UBXN1 inhibits retrovirus production and NFκB pathway. by Yani Hu (644012)

“…<p><b>(A)</b> Schematic of UBXN1 deletion and mutant constructs: yellow is N terminal UBA domain thought to bind polyubiquitin, green is coil-colied domain thought to mediate self-association, blue is UBX domain thought to interact with other proteins; <b>(B)</b> Quantification of HIV-eYFP (VSV G) production, after 293T co-transfection of HIV vector components and UBXN1 expression plasmid shown at bottom, with titer on HOS cells normalized to empty plasmid (set at 1), as measured by FACS; <b>(C)</b> Immunoblot of the various FLAG-UBXN1 mutant proteins, as detected using anti-FLAG antibody; <b>(D)</b> Quantification by FACS of HIV LTR activity in 293T cells transfected with decreasing amounts of 1–297 UBXN1 along with HIV-eYFP, as measured by eYFP MFI, normalized to empty vector (EV) (black bars); also quantification by RLU of HIV LTR-FFLUC, also normalized to EV (grey bars); underneath is shown immunoblot of transfected FLAG-tagged UBXN1 wt and AAA mutant proteins; <b>(E)</b> Quantification of transfection efficiency in 293T producers of other lentiviral vectors, as measured by eGFP/eYFP MFI by FACS in the presence of either FLAG-UBXN1 (grey bars) or EV (black bars); <b>(F)</b> As in part <b>(B)</b>, quantification of production of indicated retroviral vectors, after co-transfection of FLAG-UBXN1 (grey bars), FLAG-AAA mutant (open bars), or EV (black bars) expression plasmids along with packaging and transfer vector components and VSV G into 293T cells, with resultant titer normalized to that of EV (set at 1.0 in each case). …”