Bam blocks nuclear accumulation of pMad and dSmurf degrades cytoplasmic pMad. by Wen Lu (153883)

“…(D–H) Flies of genotype <i>TkvAct</i> (D), <i>hs-bam TkvAct</i> (E), <i>hs-bam</i> (F), <i>dSmurf^15C</i> (G), or <i>hs-bam dSmurf^15C</i> (H) were subject to a 2-h heat shock at 37° and a 4-h recovery at room temperature. …”

Supplementary Material for: Association between impaired renal function and subclinical myocardial dysfunction in patients with heart failure with preserved ejection fraction: asse... by Lin M. (4160032)

Comparison of bacterial population dynamics in the untreated and single inhibitor dose scenarios. by Paul A. Roberts (5171447)

“…Eqs <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006071#pcbi.1006071.e002" target="_blank">1</a>–<a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1006071#pcbi.1006071.e016" target="_blank">8</a> were solved using ode15s. …”

Cerebellar pathology in FTgpi mice. by Paolo Dametto (253415)

“…Western blot was decorated with POM2 antibody. (<b>D</b>) Cerebellar frozen sections were stained with DAPI (blue) and TUNEL (red) to reveal nuclei and fragmented DNA, respectively. …”

Data_Sheet_1_Diagnostic Value of Combinatorial Markers in Colorectal Carcinoma.docx by Veronika Voronova (3727030)

“…</p><p>Results: Of 20 biomarkers, 16 were significantly different between the groups (p-value ≤ 0.001); ApoA1, ApoA2 and ApoA4 levels were decreased, whereas levels of tumor antigens (e.g. carcinoembriogenic antigen) and inflammatory markers (e.g., C-reactive protein) were increased in CRC patients vs. healthy subjects. …”

NF-κB dependent regulation of PKA and FOXO1. by Yvonne Imielski (185827)

“…Reactivation of NF-κB by doxycycline treatment results in re-expression of PKA (<b>e</b>, <b>f</b>); as shown by in situ hybridisation (encoded in false colour, data from <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0030838#pone.0030838-Kaltschmidt2" target="_blank">[19]</a>). …”

Analysis of the descending aorta and carotid in untreated and PPS-treated MPS I dogs. by Calogera M. Simonaro (276724)

“…(A) The intima media of both the descending aorta and carotid is thickened (arrows) in the untreated MPS I dog due to lysosomal storage, resulting in narrowing of the lumen (*) (magnification 1X). PPS treatment decreased the thickness of the intimal media and increased the diameter of the lumen with both modes of administration, but was more significant with subQ treatment (see Tables <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153136#pone.0153136.t002" target="_blank">2</a> and <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0153136#pone.0153136.t003" target="_blank">3</a>) (B) Higher magnification (10X) of the descending aorta and carotid artery in untreated and PPS-treated MPS I dogs revealed reduced vacuolization/storage in the treated animals when compared to untreated (arrows). …”

Supplementary file 1_Scorpion-Centipede extracts mitigate ovariectomy-induced osteoporosis in mice through facilitating Cx3cr1 expression.docx by Jinghuai Ni (21023477)

“…In addition, SC treatment markedly increased Runx2, Osx, Alp, and Cx3cr1 while decreasing adipogenic genes like PPARγ and C/EBPα in the bone tissue of OVX mice and BMMSCs. …”

Critical control effort relative to classical predictions. by Samuel P. C. Brand (2633989)

“…Two scenarios for the efficacy of spraying are considered: where the excess mortality reduces the population biting rate as well as reducing the life expectancy of inoculated vectors (solid blue curves) or if it solely decreases the life expectancy of inoculated vectors (dashed blue curves). …”

DataSheet1_Statistical Analysis of the Weather Impact on Robusta Coffee Yield in Vietnam.PDF by Thi Lan Anh Dinh (12894872)

“…The data suggest that robusta coffee in Vietnam is most sensitive to two key moments: a prolonged rainy season of the previous year favoring vegetative growth, thereby increasing the potential yield (i.e., number of fruiting nodes), while low rainfall during bean formation decreases yield. …”

Quantitation of Glucocorticoid Receptor DNA-Binding Dynamics by Single-Molecule Microscopy and FRAP by Femke L. Groeneweg (535939)

Copper-Induced Deregulation of microRNA Expression in the Zebrafish Olfactory System by Lu Wang (45927)

“…Moreover, several miRNAs (e.g., miR-203a, miR-199*, miR-16a, miR-16c, and miR-25) may contribute to decreased mRNA levels of their host genes involved in olfactory signal transduction pathways and other critical neurological processes via a post-transcriptional mechanism. …”

Table1_Lipidomics analysis facilitate insight into the molecular mechanisms of urate nephropathy in a gout model induced by combination of MSU crystals injection and high-fat diet... by Guifeng Hao (14588425)

“…Lipidomics analysis revealed that altered triacylglycerol (TAG) profile, impaired mitochondrial function resulted by decreased tetra 18:2 cardiolipin, reduced 4-hydroxyalkenal (HNE) species, and elevated lysophospholipids were already present in the kidneys at early stage of renal injury, probably contributing to its occurrence and development. …”

Copper-Induced Deregulation of microRNA Expression in the Zebrafish Olfactory System by Lu Wang (45927)

“…Moreover, several miRNAs (e.g., miR-203a, miR-199*, miR-16a, miR-16c, and miR-25) may contribute to decreased mRNA levels of their host genes involved in olfactory signal transduction pathways and other critical neurological processes via a post-transcriptional mechanism. …”

Scoparone suppresses anchorage-independent growth <i>in</i><i>vitro</i> and xenograft tumor growth of DU145 cells in nude mice. by Jeong-Kook Kim (485635)

“…The number of colonies lager than 2 mm in diameter was counted and data represent the means ± S.E.M. of three independent experiments, each performed in duplicate. …”

Stability analysis of the bump in the ring attractor network. by Andres Flores-Valle (11114221)

“…E: Mean of the bump peak over the analysis time window (mean activity of the wedge neuron 16, ). …”

Copper-Induced Deregulation of microRNA Expression in the Zebrafish Olfactory System by Lu Wang (45927)

“…Moreover, several miRNAs (e.g., miR-203a, miR-199*, miR-16a, miR-16c, and miR-25) may contribute to decreased mRNA levels of their host genes involved in olfactory signal transduction pathways and other critical neurological processes via a post-transcriptional mechanism. …”

<i>Ptp4a3</i> is expressed in AOM-DSS derived colon tumors and normal tissue. by Mark W. Zimmerman (395901)

“…<i>Ptp4a3</i> was elevated 3.7-fold (** = p<0.01), while <i>Ptp4a1</i> and <i>Ptp4a2</i> levels were significantly decreased (* = p<0.0001 and p<0.05, respectively) (n = 15, bars  =  SEM). …”

Numerical simulations of the general integro-differential model (Eqs 6 and 7) in a cylindrically symmetric domain. by Zhihui Wang (88248)

“…<p>As cell kill ensues over several cell cycles, (<i>A</i>) successive cell layers next to the blood vessel (<i>r</i> = <i>r</i>_b) die out, i.e., tumor volume fraction <i>φ</i> decreases; (<i>B</i>) local drug concentration <i>σ</i> increases due to an enhancement of drug penetration; and (<i>C</i>) cell kill accelerates further from the vessel and deep into the tumor. …”

Effect of BCAA on the dexamethasone-induced protein degradation pathway in the GH-treated SDRs. by Hikaru Nishida (757003)

“…BCAA increased MuRF1 mRNA in soleus muscles. D and E. Dex increased the REDD1 and REDD2 mRNA levels, and BCAA attenuated the Dex-induced increase in REDD2 mRNA. …”