Integrating Functional Data to Prioritize Causal Variants in Statistical Fine-Mapping Studies by Gleb Kichaev (652009)

“…We validate our findings using a large scale meta-analysis of four blood lipids traits and find that the relative probability for causality is increased for variants in exons and transcription start sites and decreased in repressed genomic regions at the risk loci of these traits. …”

Table_1_Effects of anaerobic and respiratory adaptation of Lacticaseibacillus casei N87 on fermented sausages production.DOCX by Lucia Camprini (14589497)

“…The inoculation of the strain did not have any effect on the Aw values, which decreased similarly in the different samples whereas the pH was lower in A samples (5.2) and the weight loss in R samples (2.5% less than the others). …”

Image_2_Chicken CH25H inhibits ALV-J replication by promoting cellular autophagy.tif by Tingting Xie (837869)

“…Our results found that overexpression of CH25H and treatment with 25HC promoted the autophagic markers microtubule-associated protein 1 light chain 3 II (LC3II) and autophagy-related gene 5(ATG5), while decreased autophagy substrate p62/SQSTM1 (p62) expression in ALV-J infection DF-1 cells. …”

Data_Sheet_2_Scutellarin Enhances Antitumor Effects and Attenuates the Toxicity of Bleomycin in H22 Ascites Tumor-Bearing Mice.docx by Juan Nie (3508364)

“…Furthermore, BLM combined with SCU increased the protein expression of p53 and gene expression of miR-29b, and decreased the expression of TGF-β1. In vitro experiment results showed that BLM combined with SCU inhibited the viability of H22 cells and MRC-5 cells, promoted H22 cell apoptosis, up-regulated the protein expression of p53 and down-regulated the protein expression of α-SMA and collagen-I in MRC-5 cells. …”

IL-7 producing immunotherapy improves <i>ex vivo</i> T cell functions of immunosenescent patients, especially post hip fracture by Chrystel Marton (9950893)

“…In addition, stimulation led to an increased naïve T cell as well as a decreased effector memory T cell proportions compared to controls. …”

Table_2_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”

Table_4_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”

Cell quantifications of H&E, PCNA and TUNEL stainings. by Christoph Tappeiner (444164)

“…</b> After the induction of retinal degeneration using MNU, a significant increase in PCNA-positive cells, indicating proliferation, was observed in the INL (INL DMSO and INL SB431542) between days 3 and 8 (peaking at days 3 and 5). …”

Image_1_Impact of pulmonary arterial systolic pressure on patients with mitral valve disease combined with atrial fibrillation.pdf by Tie Zheng (614289)

“…</p>Results<p>A complete echocardiography was performed at baseline and after 5 years. …”

Alteration of long non-coding RNAs and mRNAs expression profiles by compound heterozygous ASXL3 mutations in the mouse brain by Songhui Zhang (11501090)

“…Results showed that ASXL3 gene expression was decreased in the cerebrum and cerebellum of mice with ASXL3 P723R*P1817A mutations. …”

Competition between CTP and 2’deoxy-2’fluoro-CTP. by Egor P. Tchesnokov (1893004)

“…Data were fitted to a dose response function in GraphPad (Prism 6.0) to determine the concentration of 2’deoxy-2’fluoro-CTP at which the amount of full-length-template product decreased by 50% (IC₅₀).…”

Three SRA-Domain Methylcytosine-Binding Proteins Cooperate to Maintain Global CpG Methylation and Epigenetic Silencing in Arabidopsis by Hye Ryun Woo (271026)

“…Interestingly, the <em>vim1 vim3</em> mutant and <em>vim</em> knock-down lines gained ectopic CpHpH methylation in the 5S rRNA genes against a background of CpG hypomethylation. …”

Table_1_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”

Table_1_Acute hyperglycemia compromises the responses of choroidal vessels using swept-source optical coherence tomography during dark and light adaptations.docx by Zhiyang Lin (284691)

“…However, only TCV (0.38 ± 0.17 mm³) and LV (0.27 ± 0.10 mm³) showed a significant increase at the time point of 5 min after ambient light.…”

Sociodemographic Disparities in Mercury Exposure from United States Coal-Fired Power Plants by Mona Q. Dai (16025606)

“…Significantly greater proportions of low-income individuals lived within 5 km of active facilities in 2020 (<i>n</i> = 277) compared to plants that retired after 2010, suggesting that socioeconomic status may have played a role in retirement. …”

16S rRNA gene profiling and genome reconstruction reveal community metabolic interactions and prebiotic potential of medicinal herbs used in neurodegenerative disease and as nootro... by Christine Tara Peterson (6482789)

“…Taxa displaying low herb responsiveness. Taxa displaying decreased average abundance >5-fold compared to controls in all herb-supplemented cultures. …”

Molecular Determinants of Juvenile Hormone Action as Revealed by 3D QSAR Analysis in <em>Drosophila</em> by Denisa Liszeková (262829)

“…When either of these electronegative atoms are replaced by carbon or the distance between them is shorter than 11.5 Å or longer than 13.5 Å, their biological activity is dramatically decreased. …”

Evaluation of the Traditional and Revised WHO Classifications of Dengue Disease Severity by Federico Narvaez (197554)

“…We evaluated the traditional and revised classification schemes against clinical intervention levels to determine how each captures disease severity using data from five years (2005–2010) of a hospital-based study of pediatric dengue in Managua, Nicaragua. …”

Image_4_Chicken CH25H inhibits ALV-J replication by promoting cellular autophagy.tif by Tingting Xie (837869)

“…Our results found that overexpression of CH25H and treatment with 25HC promoted the autophagic markers microtubule-associated protein 1 light chain 3 II (LC3II) and autophagy-related gene 5(ATG5), while decreased autophagy substrate p62/SQSTM1 (p62) expression in ALV-J infection DF-1 cells. …”

Table_6_Sex and age effects on gray matter volume trajectories in young children with prenatal alcohol exposure.XLSX by Madison Long (18336297)

“…Using longitudinal T1-weighted MRI, the present study characterized gray matter volume development in young children with PAE (N = 42, 84 scans, ages 3–8 years) compared to unexposed children (N = 127, 450 scans, ages 2–8.5 years). Overall, we observed altered global and regional gray matter development trajectories in the PAE group, wherein they had attenuated age-related increases and more volume decreases relative to unexposed children. …”