Image_2_Consecutive Hypoxia Decreases Expression of NOTCH3, HEY1, CC10, and FOXJ1 via NKX2-1 Downregulation and Intermittent Hypoxia-Reoxygenation Increases Expression of BMP4, NOTCH1, MKI67, OCT4, and MUC5AC via HIF1A Upregulation in Human Bronchial Epithelial Cells.TIF by Yung-Yu Yang (9343376)

“…In both the normal and diseased HBE cells, intermittent H/R significantly increased HIF1A, BMP4, NOTCH1, MKI67, OCT4, and MUC5AC expression, while consecutive hypoxia significantly decreased NKX2-1, NOTCH3, HEY1, CC10, and FOXJ1 expression. …”

Activated CD4+ CD45RO+ memory T-cells decrease secretion of soluble caspase-1 and P2X7R mRNA expression in monocytes leading to a reduced response upon ATP binding. by Vanessa Beynon (153924)

“…A significant decrease of soluble Caspase-1 in the supernatant of cells co-cultured with activated memory T-cells was observed both in the presence and absence of IFNβ; b) intracellular levels of pro-IL-1β measured with an ELISA specific for the immature precursor of IL-1β showed a significant increase in pro-IL-1β levels in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3), cell lysates from adherent monocytes were obtained after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP c) the ratio of intracellular pro-IL-1β to released soluble Caspase-1 is significantly increased in the presence of human activated CD4+CD45RO+ memory T-cells (n = 3). d) <i>P2X7R</i> mRNA expression in monocytes cultured overnight with activated CD4+CD45RO+ memory T-cells is decreased with and without addition of exogenous IFNβ (n = 3), mRNA was isolated from adherent monocytes after removal of non-adherent T-cells after addition of LPS and prior to incubation with ATP (Data are shown as means ± SD of duplicate cultures; *p<0.05; **p<0.01 employing repeated measures ANOVA with post-hoc Bonferroni adjustment for multiple comparisons to avoid random correlations); e) Ca²⁺-influx measurement in monocytes cultured with activated human CD4+CD45RO+ memory T-cells in the presence of IFNβ demonstrates the absence of slow sustained Ca²⁺-influx mediated by ATP binding to the purinergic P2X7-receptor (representative of 3 independent experiments); f) Annexin V staining of monocytes coincubated with T-cells and stimulated with LPS was measured by flow cytometry (representative flow cytometry histogram of n = 5).…”

RDV and EIDD2801 EC₅₀ and fold-change in VeroE6-ACE2-TMPRSS2. by Agnieszka M. Szemiel (10196243)

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Carbon−Sulfur Bond Formation via Alkene Addition to an Oxidized Ruthenium Thiolate by Craig A. Grapperhaus (1666657)

“…During oxidation, the absorption bands of <b>1b</b> at 540, 797, and 1041 nm decrease in intensity. The resulting complex <b>[2a]</b><b>⁺</b> displays a single redox couple at +804 mV. …”

Tunable White-Light Emission in Single-Cation-Templated Three-Layered 2D Perovskites (CH₃CH₂NH₃)₄Pb₃Br_{10–<i>x</i>}C... by Lingling Mao (513927)

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SrpR binds the centromere-like region <i>srpC</i>. by Nicolas Carraro (650366)

Visualization and quantification of adhered and internalized <i>C</i>. <i>difficile</i> spores in the ileum and colonic mucosa during aging. by Pablo Castro-Córdova (5614352)

Data_Sheet_3_The German Quality Network Sepsis: Evaluation of a Quality Collaborative on Decreasing Sepsis-Related Mortality in a Controlled Interrupted Time Series Analysis.pdf by Daniel Schwarzkopf (4984601)

“…This study presents the evaluation of a quality collaborative, which aimed to decrease sepsis-related hospital mortality.…”

Data_Sheet_1_The German Quality Network Sepsis: Evaluation of a Quality Collaborative on Decreasing Sepsis-Related Mortality in a Controlled Interrupted Time Series Analysis.pdf by Daniel Schwarzkopf (4984601)

“…This study presents the evaluation of a quality collaborative, which aimed to decrease sepsis-related hospital mortality.…”

Baseline Characteristics by eGFR Category. by Jennie Lin (671926)

Gfi1 is required for the generation of LMPPs. by Jennifer Fraszczak (457829)

“…(K) HSC (Lin^-Sca1⁺c-Kit⁺Flt3^-), MPP (Lin^-Sca1⁺c-Kit⁺Flt3^low), LMPP (Lin^-Sca1⁺c-Kit⁺Flt3⁺) and CLP (Lin^-IL7R⁺Sca1⁺c-Kit⁺) were gated and analyzed for cell death by Annexin V staining. (L) Schematic representation of lymphoid development from Hematopoietic Stem Cells (HSC) to Pro B cells with the different steps including Multipotent Primed Progenitors (MPP), Lymphoid Primed Multipotent Progenitors (LMPP), Common Lymphoid Progenitors (CLP) and Pre-pro B cells. …”

Overexpression of DJ-1 full length prior to oxidative stress leads to decreased levels of H₂O₂-induced ROS generation by RPE cells. by Karen G. Shadrach (429721)

A flowchart describes the stepwise analysis of missense SNPs in the human PC and illustrates the computational tools used in the study. by Mahvash Farajzadeh-Dehkordi (17468232)

(a) and (b) Time series of weekly aggregates of norovirus GII RNA concentrations (filled shapes with solid lines), detection frequency (open shapes with dashed lines), and national... by Jay C. Bullen (10232606)

Summary of the changes in protein expression and cardiac function in the Pkd2+/- mice examined over a 9 mo period. by Ivana Y. Kuo (707543)

HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 3 by Qin Huang (49441)

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SDG decreases iron-induced MMP gene expression in H9c2 cells. by Stephanie Puukila (568109)

HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 2 by Qin Huang (49441)

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HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 1 by Qin Huang (49441)

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HEWL interacts with dissipated oleic acid micelles, and decreases oleic acid cytotoxicity - Fig 4 by Qin Huang (49441)

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