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99641
A pharmacogenomic pathway of the artificial simulation model.
Published 2014“…<p>The figure illustrates the pathway of the artificial simulation model used for datasets (i) and (ii). Each regulation is represented by (i) a linear and (ii) a nonlinear function, such as <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0105942#pone.0105942.e017" target="_blank">Eq. (3)</a>. …”
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99642
Transmembrane and Ubiquitin-Like Domain Containing 1 (Tmub1) Regulates Locomotor Activity and Wakefulness in Mice and Interacts with CAMLG
Published 2010“…The two proteins were also found to be co-localized to the cytoplasm when expressed in HEK cells. …”
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99643
Myocardial ischemia-reperfusion enhances transcriptional expression of endothelin-1 and vasoconstrictor ET<sub>B</sub> receptors via the protein kinase MEK-ERK1/2 signaling pathway...
Published 2017“…<p><b>(A)</b> The mRNA expression levels of ET-1 were sigificantly upregulated at 3 h of IR. …”
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99644
Data_Sheet_1_Serotype distribution, clinical characteristics, and antimicrobial resistance of pediatric invasive pneumococcal disease in Colombia during PCV10 mass vaccination (201...
Published 2024“…</p>Conclusion<p>The prevalence of PCV10-included serotypes decreased, while serotypes 19A and 6C increased, with Spn19A being associated with multiresistance. …”
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99645
Data_Sheet_2_Serotype distribution, clinical characteristics, and antimicrobial resistance of pediatric invasive pneumococcal disease in Colombia during PCV10 mass vaccination (201...
Published 2024“…</p>Conclusion<p>The prevalence of PCV10-included serotypes decreased, while serotypes 19A and 6C increased, with Spn19A being associated with multiresistance. …”
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99646
Image_1_Serotype distribution, clinical characteristics, and antimicrobial resistance of pediatric invasive pneumococcal disease in Colombia during PCV10 mass vaccination (2017–202...
Published 2024“…</p>Conclusion<p>The prevalence of PCV10-included serotypes decreased, while serotypes 19A and 6C increased, with Spn19A being associated with multiresistance. …”
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99647
Simulations of Model (2) on the interruption of treatment and infection progression.
Published 2013“…<p>(a) Treatment is interrupted for 1 day at day 3 and continues for the rest of the 9-day therapy. …”
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99648
A model for zebrafish sex determination: oocyte survival regulated by Tp53-mediated apoptosis can alter gonad fate.
Published 2013“…This model suggests that different levels of germ cell apoptosis (indicated as a red gradient box from low (white) to high apoptosis (red)) has the potential to tip the fate of the gonad: high apoptosis (e.g <i>fancl<sup>−/−</sup></i> mutants) tips fate towards the male pathway, while low apoptosis (e.g. …”
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99649
Hippocampal volume changes along the rostrocaudal axis in the COUP-TFI mutant mice.
Published 2025“…A dense distribution of YFP<sup>+</sup> cells was found in the caudal CA1 (b<sub>2</sub>). <b>(C)</b> Changes in YFP<sup>+</sup> cell distribution in the COUP-TFI mutant hippocampus (marked by yellow outline). …”
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99650
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99651
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99652
Data_Sheet_1_Immediate and Delayed Response of Simulated Human Atrial Myocytes to Clinically-Relevant Hypokalemia.PDF
Published 2021“…</p><p>(ii) A second much slower electrophysiological response (developing 5–10 minutes after [K<sup>+</sup>]<sub>o</sub> is reduced) results from alterations in the intracellular electrolyte balance. …”
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99653
Comparative evolution of plants and cars.
Published 2018“…<p>(a) In 1885, Karl Benz was among the automobile’s first producers, and in 1908, the Ford Motor Company pioneered the first mass produced automobile, the Model T [<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0198044#pone.0198044.ref005" target="_blank">5</a>]. …”
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99654
Length distribution of assembled sequences.
Published 2016“…(B) The counts of unigenes without matches (with a cut-off E-value of 10E-5) in the NCBI NR database decreases along with length. …”
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99655
Gene expression analyses in Enpep silenced HL-1 atrial cardiomyocytes.
Published 2017“…<p>Note that Enpep is decreased (siEnpep), leading to decreased expression of <i>Pitx2c</i> but not of <i>Wnt8a</i>, <i>Wnt11</i>, <i>Zfhx3</i>, <i>Cacna1c</i> or <i>Scn5a</i>. …”
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99656
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99657
CAZy gene expression.
Published 2012“…Cells were grown in glucose (48 h), washed and transferred to straw (24 h) and then glucose was added (downward arrow) followed by a further 5 h incubation. (A) Percentage of total mRNA (calculated from RPKM values) represented by CAZy family genes from each condition of the transcriptome study. …”
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99658
Fluorescence recovery after photobleaching (FRAP)
Published 2011“…FRET is the non-radiative transfer of energy between two fluorophores. The energy transfer efficiency decreases proportionally to the sixth power of the distance between the two fluorophores, and hence occurs only when the molecules harboring the fluorophores are in contact or very close proximity. …”
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99659
Data Sheet 1_Clinical pharmacist interventions in medication review for medication optimization in older hospitalized adults with mental disorders and somatic comorbidities: eviden...
Published 2025“…The number of PIMs also significantly decreased (p < 0.001), with reductions of 29.5% (from 308 to 217) based on the Priscus List and 17.5% (from 343 to 283) according to the Beers Criteria. …”
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99660
Table_2_Multi-omics analysis identifies IgG2b class-switching with ALCAM-CD6 co-stimulation in joint-draining lymph nodes during advanced inflammatory-erosive arthritis.docx
Published 2023“…Integration of single-cell and spatial transcriptomics revealed the increased IgG2b<sup>+</sup> plasma cells localized in MARCO<sup>+</sup> peri-follicular medullary sinuses. A concomitant decreased Fth1 expression (Early 2.5 ± 0.74 vs Advanced 1.0 ± 0.50 counts, p<0.001) within Advanced PLN sinuses was associated with accumulation of iron-laden Prussian blue positive macrophages in lymph nodes and synovium of Advanced TNF-Tg mice, and further validated in RA clinical samples. …”