Three Ca_V3.3 variants left-shift the window current, while the A398V completely abolishes the window current. by Yousra El Ghaleb (22075892)

Subjects:

NaSal increased the excitability of 5-HTergic neurons, but decreased that of GABAergic neurons in the DRN of the ChR2 transgenic mouse. by Yan Jin (143500)

“…(D) Sample traces (left panel) and group data (right panel, paired Student’s <i>t</i>-test) showing that NaSal suppressed the firing of GABAergic neurons evoked by laser light (1 s, 5.5 mW, 473 nm). (E) Sample recordings from a GABAergic neuron showing that NaSal decreased voltage responses to a series of hyperpolarizing currents (-10 to -60 pA, -10 pA/step, duration: 500 ms). …”

Decreased immunofluorescence during multiplex staining. by Sandrine Prost (38667)

“…<p>Serial sections were stained with 1 to 5 different markers (Marker 1, MHCII Qdot 705Vivid; Marker 2, HO1 Qdot 605Vivid; Marker 3, CD163 Qdot 565; Marker 4, CD206 Qdot 655Vivid; Marker 5, CD68 streptavidin Qdot 525). …”

Decreased IL-7 responses in ICL. by Florence Bugault (278171)

“…A dose dependent response is observed, with a higher pSTAT5 expression at high IL-7 dose (2 nM) than at low IL-7 dose (20 pM). …”

At lower concentrations, METH decreases LTP. by Jarod Swant (246454)

“…At 0.1 µM METH, LTP was 1.58±.08 [<i>n</i> = 13(5)] (Fig. 1B); at 1 µM METH, LTP was 1.50±.07 [<i>n</i> = 13(7)] (Fig. 1C); at 10 µM METH, LTP was 1.58±.07 [<i>n</i> = 14(8)] (Fig. 1D); at 30 µM METH, LTP was 1.37±.06 [<i>n</i> = 15(4)] (Fig. 1E); and at 60 µM METH, LTP was 1.32±.24 [<i>n</i> = 4(2)] (Fig. 1E). …”

Cyclooxygenase inhibition decreases immune control of fungal germination and invasive hyphal growth. by Savini Thrikawala (5690510)

Phagocytosis is sharply decreased in CF macrophages. by Karin Simonin-Le Jeune (464354)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

G9a decreases Rhox5 expression. by Mayumi Sugimoto (151133)

CpG/c stimulated CLL B cells exhibit decreased survival and decreased activation of the Wnt pathway. by Albert Gutierrez Jr. (342562)

Maternal exposure to U-46619 decreases fetal body weight at E19 compared to sham pups. by Camille M. Fung (844334)

“…<p>Pregnant mice were exposed to a TXA₂- analog (U-46619) or vehicle via micro-osmotic pump infusion from E12.5 until birth (term ~20 days). …”

Effect of SNX5 S226 phosphorylation on macropinocytosis. by Nao Itai (5954666)

Subjects:

Changes in the localization of SNX5 S226 mutants. by Nao Itai (5954666)

Subjects:

Delphinidin alters VEGF-A splicing to increase VEGF-A₁₆₅b and decrease total VEGF-A expression. by Megan Stevens (3964886)

“…<p><b>A)</b> Treatment of podocytes with delphinidin chloride (10 μg/ml) under normal glucose (NG; 5 mM glucose + 25 mM mannitol) and high glucose (HG; 30 mM glucose, 1 ng/ml TNFα, 1 ng/ml IL-6, and 100 nM insulin) for 48 hrs increased the protein expression of VEGF-A₁₆₅b relative to total VEGF-A₁₆₅ (quantified in <b>B</b>; *p<0.05 vs NG, †p<0.05 vs HG; n = 3 biological repeats; One-way ANOVA with Bonferroni post-hoc test for comparison between pairs; <b>A</b>—the same blot was first probed with VEGF-A₁₆₅b before stripping and reprobing with panVEGF-A). …”

Table_5_Sub-Inhibitory Concentrations of Chlorhexidine Induce Resistance to Chlorhexidine and Decrease Antibiotic Susceptibility in Neisseria gonorrhoeae.DOCX by Jolein G. E. Laumen (11754755)

Simulated effects of increased pCREB combined with decreased pCaMKIIα on bistability. by Yili Zhang (540283)

“…<p>(A1) Modification of model. Increased basal phosphorylation of CREB <i>k</i>_{<i>basalp_creb</i>}, concurrent with decreased basal phosphorylation of CaMKIIα <i>k</i>_{<i>basalp_CaMKII</i>}, in the absence of the effects of MeCP2/HDAC2/Sin3a (red) ([<i>E</i>_<i>comp</i>] = 0; [<i>E</i>_<i>MeCP2</i>] = 0). …”

Intervention with MLKL decreased neutrophil death and protected mice against <i>E. coli</i> pneumonia. by Qinyu Luo (13000956)

PLD inhibitors decrease PLD2 expression in foci of lungs following xenotransplantation. by Karen M. Henkels (3350273)

“…<p>(<b>A</b>) Primary tumor volume from xenotransplanted mice in the presence or absence (“control” = vehicle only) of PLD inhibitors delivered by Alzet pumps, as in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0166553#pone.0166553.g001" target="_blank">Fig 1</a> legend. …”

Intervention with MLKL decreased neutrophil death and protected mice against <i>E. coli</i> pneumonia. by Qinyu Luo (13000956)

Muscle-specific knockdown of <i>nSMase</i> decreases a subset of ceramide species that are decreased in <i>Gba1b</i> mutants. by Kathryn A. Jewett (3756811)