Six weeks of voluntary wheel running decreases 5-HT_2C mRNA expression in the medial dorsal striatum. by Benjamin N. Greenwood (295216)

Specific Cyt2 triggering increases CTLA-4 expression and decreases LAT phosphorylation. by Siobhan Ni Choileain (124123)

SPL treatment decreases diabetes-induced decrement in protein expression of cldn-5 in glomeruli (GL) and cldn-2 and occldn in proximal tubules (PT). by Eduardo Molina-Jijón (4020464)

“…<p>SPL prevents diabetes-induced decrease of cldn-5 protein expression (A and B) in GL, and mRNA (F) and protein expression of cldn-2 (A and C), and protein expression of occldn (A and D) in PT (<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0177362#pone.0177362.s002" target="_blank">S2 Fig</a>). …”

Cortical distribution of neurons born at E11.5, E13.5, E15.5, or E17.5 in P0 mice. by Qingfa Chen (739620)

“…In <i>Nestin;Epha4</i>^<i>fx/fx</i> mice, a larger number of CTIP2+ cells was co-labeled with BrdU at E11.5 but fewer were co-labeled at E13.5 compared to controls (C), whereas in <i>GFAP;Epha4</i>^<i>fx/fx</i> mice, the number of co-labeled cells was similar to that of controls at both E11.5 and E13.5 (D). …”

Exposure to low CO₂ levels decreases ER cholesterol levels. by Nityanand Bolshette (17396845)

“…<b>(B)</b> Bioluminescence recordings from the different conditions as depicted in <b>(A)</b>, the arrow indicates the time CO₂ was shifted from 5% to 1% (mean ± SE, <i>n</i> = 4 biological replicates per condition, AUC for 0 mM 0.34 ± 0.007, 1.59 ± 0.004 (<i>P</i> < 0.0001), 0.5 mM 1.00 ± 0.023, 2.68 ± 0.04 (<i>P</i> < 0.0001), 1 mM 1.66 ± 0.07, 3.34 ± 0.04 (<i>P</i> < 0.0001), 3 mM 2.06 ± 0.02, 2.79 ± 0.07 (<i>P</i> < 0.0001), 5 mM 2.02 ± 0.05, 2.43 ± 0.06 (<i>P</i> < 0.002), 7 mM 1.85 ± 0.01, 1.77 ± 0.02 (<i>P</i> < 0.02) two-sided Student’s <i>t</i> test). …”

sEH inhibition decreased fasting glucose levels in type 2 diabetic mice. by Kristen L. Zuloaga (563616)

PTB is associated with decreased spontaneous production of Type 1, 2, 17 and immunoregulatory cytokines. by Nathella Pavan Kumar (129299)

Repeated dosing of P2Y13R agonist decreases HDL-C. by Marine Goffinet (90787)

Cardiac Development in Zebrafish and Human Embryonic Stem Cells Is Inhibited by Exposure to Tobacco Cigarettes and E-Cigarettes by Nathan J. Palpant (127912)

“…In definitive human cardiomyocytes, both e-cigarette- and tobacco cigarette-treated samples showed reduced expression of sarcomeric genes such as MLC2v and MYL6. …”

Cell proliferation in the MGE is not altered in Fgfr1 mutants at E13.5. by Karen Müller Smith (613941)

Stimulation of α2-adrenergic receptors inhibits hippocampal precursor activity and decreases neurogenesis. by Dhanisha J. Jhaveri (577341)

“…<p>(A) Treatment of hippocampal precursor cells with α2-adrenergic receptor agonist at 10 uM significantly decreased neurosphere formation compared to the control. …”

Tunicamycin produces a concentration- and time-dependent decrease in cell viability in SH-SY5Y cells concomitant with caspase-3 activation. by Arindam P. Ghosh (317870)

“…<p>(A) Treatment of SH-SY5Y cells with tunicamycin (0.1–5µM) for 24 h caused a progressive decrease in cell viability as measured by Calcein AM cleavage assay. …”

TLR2-mediated inhibition of IFN-γ induction of CXCL11 and CIITA decreases expression of protein products. by Sarah A. Benson (371554)

(A) The temperature sensitive allele of <i>HEM1</i> leads to a significant decrease in the endogenous levels of Cia2 and Mms19. by Ifat Lev (469072)

The raw data for Fig 5B. by Hongjoo An (21703199)

Subjects:

Sonication decreases toxicity of the Vicilin, Cupin-1.1, and Cupin-1.2 fibrils. by Kirill S. Antonets (4807410)

DN1 and DN2 cells are preferentially increased by TSLP in FTOC and decreased in TSLPRFTOC by Qi Jiang (33521)

Characteristics of patients with AKI diagnosed using KDIGO definition versus patients diagnosed with AKI by eKDIGO only by the decrease in sCr (deKDIGO). by Marina Wainstein (12437091)

MeCP2 expression in glutamatergic dLGN neurons decreases upon dark-rearing. by Yuki Yagasaki (402238)

Nitrile in the Hole: Discovery of a Small Auxiliary Pocket in Neuronal Nitric Oxide Synthase Leading to the Development of Potent and Selective 2‑Aminoquinoline Inhibitors by Maris A. Cinelli (1309419)

“…We previously developed a class of membrane-permeable 2-aminoquinoline inhibitors and later rearranged the scaffold to decrease off-target binding. …”