CA alleviated DOX-induced myocardial injury <i>in vitro</i> and <i>in vivo</i>. by Meijiao Mao (10677555)

Stability parameters for SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

Kinetic parameters of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

<i>T</i>_m values of SpGrx3 WT and mutants. by Trang Van Tran (16913946)

“…Hydrophilic-to-hydrophobic substitutions were made in the aromatic cluster, in β1 (E5V and Y7F), adjacent β2 (Y32F and Y32L), both β1 and β2 (E5V/Y32L), and short α2 (R47F). …”

DYRK2 Negatively Regulates Cardiomyocyte Growth by Mediating Repressor Function of GSK-3β on eIF2Bε by Celine S. Weiss (453817)

“…</p><p>Results</p><p>(1) Under baseline conditions eIF2Bε transgenic mice showed no difference in cardiac phenotype compared to wild type, whereas in the mutant eIF2Bε-S⁵³⁵A an increase in LV/tibia length (7.5±0.4 mg/mm vs. 6.2±0.2 mg/mm, p<0.001) and cardiomyocyte cross sectional area (13004±570 vs. 10843±347 RU, p<0.01) was observed. (2) Cardiac overexpression of eIF2Bε did not change the response of the heart to pathologic stress induced by chronic isoproterenol treatment. (3) Cardiac overexpression of the eIF2Bε transgene was followed by overexpression of DYRK2 which is known to prime the inhibitory action of GSK-3β on eIF2Bε, while DYRK1A and GSK-3β itself were not increased. (4) In C57BL/6 mice after 48 h of isoproterenol-stimulation or aortic banding, eIF2Bε was increased and DYRK2 was concomitantly decreased. (5) In line with these in vivo findings, siRNA knockdown of DYRK2 in cultured cardiomyocytes resulted in decreased levels of p(S535)- eIF2Bε, (6) whereas adenoviral induced overexpression of DYRK2 was accompanied by clearly increased phosphorylation of eIF2Bε, indicating a coordinated response pattern (7) Adenoviral induced overexpression of DYRK2 leads to significantly reduced cardiomyocyte size and diminishes hypertrophic response to adrenergic stimulation.…”

Effect on Physical Activity of a Randomized Afterschool Intervention for Inner City Children in 3rd to 5th Grade by Scott E. Crouter (759136)

“…After adjusting for accelerometer wear time and other design factors, light and moderate-to-vigorous PA (MVPA) increased in the nutrition+PA group (+21.5±14.5 and +8.6±8.0 min^.d^-1, respectively) and decreased in the nutrition only group (-35.2±16.3 and -16.0±9.0 min<sup>.…”

Cancellous bone microarchitecture assessed by μCT of the distal femur from 8.5–9 week old <i>Notch3</i>^{<i>em1Ecan</i>} mutant (gray bars) male mice and sex-matched litter... by Ernesto Canalis (516050)

Administration of BL-7010 (Polymers A and B) decreased CD3⁺ intraepithelial cells in villi tips of gliadin-sensitized mice. by Justin L. McCarville (432593)

Cortical bone microarchitecture assessed by μCT of the mid-diaphyseal femur from 8.5–9week old <i>Notch3</i>^{<i>em1Ecan</i>} mutant (gray bars) male mice and sex-matched l... by Ernesto Canalis (516050)

Δ40p53 alters WTp53 function; Δ40p53:WTp53 fails to induce eRNA transcription despite similar genomic occupancy vs. WTp53. by Cecilia B. Levandowski (11238230)

“…Nutlin-treated WTp53 or Δ40p53:WTp53 cells. Raw data for panels A–C, E, and G in <b><a href="http://www.plosbiology.org/article/info:doi/10.1371/journal.pbio.3001364#pbio.3001364.s028" target="_blank">S2 Data</a></b>. …”

Full model fit of predicting choosing the right option on screen during subsequent choices in the long horizon (choices 2–4; shown in Fig 3E and described in detail in the Material... by Caroline I. Jahn (14522732)

Treatment with either Salubrinal or GSK2606414 altered the levels of p-eIF2α in medulloblastoma cells. by Stephanie Jamison (323751)

“…(E, F) Western blot analysis showed that treatment with GSK2606414 (25 μM) noticeably decreased the level of p-eIF2α in Daoy cells. …”

LTB-PDM is associated with decreased spontaneously expressed and antigen - induced frequency of CD4⁺ mono -, dual - and/or multi - functional Th1 cells. by Nathella Pavan Kumar (129299)

LTB-PDM is associated with decreased spontaneously expressed and antigen - induced frequency of IL-4⁺CD4⁺ Th2 cells. by Nathella Pavan Kumar (129299)

Courtship Conditioning Learning and Memory in MB Output Neurons. by Shelby A. Montague (3232929)

The shortened version of the Edinburgh Handedness Inventory encompasses 4 items (e.g. writing) scored on a 5-point scale ranging from:” Always right; usually right; both equally; u... by Marcel F. Hinss (14675457)

a) Number weighted mean volume of AEII during postnatal development and in adults.... by Julia Hüttmann (22656283)

“…<p>a) Number weighted mean volume of AEII during postnatal development and in adults. …”

Rab10 is required for methamphetamine-induced activity in <i>D</i>. <i>melanogaster</i>. by Scott M. Vanderwerf (785324)

The CZA97.012 SOSIP.664-trimer structure. by Rajesh P. Ringe (3118764)

Distribution of the global population in 2020 [4] and prevalence of global Parkinson’s disease in 2016, by age [5]. by Sasivimol Virameteekul (11868977)