Histogram of the infection age when one infects others. by Xiaodan Sun (1467613)

“…The infectivity decreased by 1/2 at the primary stage; (c). The infectivity decreased by 1/2 at the asymptomatic stage; (d). …”

Supplementary Material for: ctDNA in Neuroendocrine Carcinoma of Gastroenteropancreatic Origin or of Unknown Primary: The CIRCAN-NEC Pilot Study by Gerard L. (10123463)

“…Molecular response was defined as a decrease of at least 30% of the mutant allele fraction. …”

Differences in Gene Expression between Mouse and Human for Dynamically Regulated Genes in Early Embryo by Elo Madissoon (608322)

“…Several large-scale studies have been conducted to identify gene expression patterns for the first five days of human development, and many functional studies utilize mouse as a model system. …”

Modulation of synaptic transmission by capsaicin at the first sensory synapse in spinal cord. by Joseph A. Jeffry (259692)

“…Application of capsaicin (2 µM) increased the frequency of sEPSCs in a reversible manner. …”

Effect of XO inhibitor allopurinol (ALLO) on IH-induced autonomic dysfunction. by Jayasri Nanduri (467086)

“…</b> HIF-2α degradation in adrenal medullae. Data presented in A–E are mean ± S.E.M. from 8 rats in each group. …”

In situ X-ray tomography imaging of soil water and cyanobacteria from biological soil crusts undergoing desiccation by Estelle Couradeau (192890)

DataSheet_1_Improving anti-tumor efficacy of low-dose Vincristine in rhabdomyosarcoma via the combination therapy with FOXM1 inhibitor RCM1.pdf by Johnny Donovan (14555891)

DataSheet_1_Improving anti-tumor efficacy of low-dose Vincristine in rhabdomyosarcoma via the combination therapy with FOXM1 inhibitor RCM1.pdf by Johnny Donovan (14555891)

Data from: Responses of subsoil organic carbon to climate warming and cooling is determined by microbial community rather than its molecular composition by Yuzhang Li (20150214)

“…However, warming elevated fungal-to-bacterial biomass ratio (F/B) and gram-positive to gram-negative bacterial biomass ratio (G+/G-) by 15.0% and 8.6%, respectively, whereas cooling reduced them by 4.5% and 9.6%. Warming reduced SOC storage by directly increasing F/B and G+/G- and indirectly decreasing the soil carbon-to-nitrogen ratio, whereas cooling enhanced SOC storage primarily by decreasing F/B. …”

CARM1 drives mitophagy and autophagy flux during fasting-induced skeletal muscle atrophy by Derek W. Stouth (17475753)

“…</p> <p><b>Abbreviation</b>: ADMA: asymmetric dimethylarginine; AKT/protein kinase B: AKT serine/threonine kinase; AMPK: AMP-activated protein kinase; ATG: autophagy related; BECN1: beclin 1; BNIP3: BCL2 interacting protein 3; CARM1: coactivator associated arginine methyltransferase 1; Col: colchicine; CSA: cross-sectional area; CTNS: cystinosin, lysosomal cystine transporter; EDL: extensor digitorum longus; FBXO32/MAFbx: F-box protein 32; FOXO: forkhead box O; GAST: gastrocnemius; H₂O₂: hydrogen peroxide; IMF: intermyofibrillar; LAMP1: lysosomal associated membrane protein 1; MAP1LC3B: microtubule associated protein 1 light chain 3 beta; mKO: skeletal muscle-specific knockout; MMA: monomethylarginine; MTOR: mechanistic target of rapamycin kinase; MYH: myosin heavy chain; NFE2L2/NRF2: NFE2 like bZIP transcription factor 2; OXPHOS: oxidative phosphorylation; PABPC1/PABP1: poly(A) binding protein cytoplasmic 1; PPARGC1A/PGC-1α: PPARG coactivator 1 alpha; PRKN/parkin: parkin RBR E3 ubiquitin protein ligase; PRMT: protein arginine methyltransferase; Sal: saline; SDMA: symmetric dimethylarginine; SIRT1: sirtuin 1; SKP2: S-phase kinase associated protein 2; SMARCC1/BAF155: SWI/SNF related, matrix associated, actin dependent regulator of chromatin subfamily c member 1; SOL: soleus; SQSTM1/p62: sequestosome 1; SS: subsarcolemmal; TA: tibialis anterior; TFAM: transcription factor A, mitochondrial; TFEB: transcription factor EB; TOMM20: translocase of outer mitochondrial membrane 20; TRIM63/MuRF1: tripartite motif containing 63; ULK1: unc-51 like autophagy activating kinase 1; VPS11: VPS11 core subunit of CORVET and HOPS complexes; WT: wild-type.…”

Data_Sheet_1_Life-long consumption of high level of fruits and vegetables reduces tumor incidence and extends median lifespan in mice.PDF by Weimin Guo (2634919)

“…Long-term FV supplementation reduced systemic inflammation and blood lipids.</p>Conclusion<p>We provide the first causal evidence that life-long intake of a diet, containing a high level and large variety of FV, decreases tumor incidence and extends median lifespan in mice fed a western-style high-fat diet. …”

DataSheet1_Adolescent Binge Alcohol Enhances Early Alzheimer’s Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation.zip by Alexandra Barnett (12458778)

“…The 3xTg-AD mouse model (APPSwe, tauP301, Psen1^tm1Mpm) which features amyloid (Aβ) and tau pathology beginning at 6–12 months underwent adolescent intermittent ethanol (AIE, 5 g/kg/d, i.g., P25-55) with assessment of AD pathologic mediators at P200. …”

Image4_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.PNG by Agnese Brokāne (14561396)

“…Next, the results were validated in an independent cohort of plasma EVs from 31 PCa and 31 BPH patients.</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”

Table1_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.DOCX by Agnese Brokāne (14561396)

“…Next, the results were validated in an independent cohort of plasma EVs from 31 PCa and 31 BPH patients.</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”

<i>Lin28B</i> Is an Oncofetal Circulating Cancer Stem Cell-Like Marker Associated with Recurrence of Hepatocellular Carcinoma by Shu-Wen Cheng (484650)

“…It is also reported to be a potential marker for cancer stem cells. Therefore, we sought to verify oncofetal-stemness characters of <i>Lin28B</i> and test its potential as a circulating cancer stem cell-like marker in adult HCC patients. …”

Image2_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.PNG by Agnese Brokāne (14561396)

“…Next, the results were validated in an independent cohort of plasma EVs from 31 PCa and 31 BPH patients.</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”

Data_Sheet_1_Life-long consumption of high level of fruits and vegetables reduces tumor incidence and extends median lifespan in mice.PDF by Weimin Guo (2634919)

“…Long-term FV supplementation reduced systemic inflammation and blood lipids.</p>Conclusion<p>We provide the first causal evidence that life-long intake of a diet, containing a high level and large variety of FV, decreases tumor incidence and extends median lifespan in mice fed a western-style high-fat diet. …”

Image3_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.PNG by Agnese Brokāne (14561396)

“…Next, the results were validated in an independent cohort of plasma EVs from 31 PCa and 31 BPH patients.</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”

Upregulation of polycistronic microRNA-143 and microRNA-145 in colonocytes suppresses colitis and inflammation-associated colon cancer by Urszula Dougherty (9920988)

“…Using TargetScan, miR-145, miR-148a, and miR-152 were predicted to regulate ADAM17. miR-143 was also investigated as miR-143 and miR-145 are co-transcribed and associated with decreased tumour growth. …”

Image1_Validation of potential RNA biomarkers for prostate cancer diagnosis and monitoring in plasma and urinary extracellular vesicles.PNG by Agnese Brokāne (14561396)

“…Next, the results were validated in an independent cohort of plasma EVs from 31 PCa and 31 BPH patients.</p><p>Results: We found that the levels of NKX3-1 (p = 0.0008) in plasma EVs, and tRF-Phe-GAA-3b (p < 0.0001) tRF-Lys-CTT-5c (p < 0.0327), piR-28004 (p = 0.0081) and miR-375-3p (p < 0.0001) in urinary EVs significantly decreased after radical prostatectomy suggesting that the main tissue source of these RNAs is prostate and/or PCa. …”