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The NK1-receptor antagonist ezlopitant significantly decreases voluntary intake of sucrose using the drinking in the dark model in mice.
Published 2013“…<p>The highest dose of ezlopitant (15 mg/kg) decreased consumption of 5% sucrose (<b>A</b>). However, ezlopitant treatment failed to induce a significant decrease in ethanol consumption compared to vehicle (<b>B</b>). …”
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Decreased LIN-35/Rb contributes to the RNAi hypersensitivity of <i>mir-35-41(gk262)</i> worms.
Published 2012“…Error bars represent the standard error of the mean (s.e.m) for at least two independent experiments.…”
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1347
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1348
Blocking CD88 decreased ANCA antigen translocation, ANCA-induced respiratory burst and degranulation in C5a-primed neutrophils.
Published 2013“…B: blocking CD88 decreased C5a-primed neutrophils expression of membrane-bound PR3 (mPR3). …”
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Adaptation to cool temperature decreases basal and stimulated lipolysis and increases <i>de novo</i> lipogenesis and TAG synthesis.
Published 2021“…ACC, acetyl-CoA carboxylase; ATGL, adipose triglyceride lipase; GSEA, gene set enrichment analysis; FASN, fatty acid synthase; HSL, hormone-sensitive lipase; NEFA, nonesterified fatty acid; PL, phospholipid; TAG, triacylglycerol; TOFA, 5-(tetradecyloxy)-2-furoic acid.…”
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1354
Decreased dissemination and parasite load after adoptive transfer of <i>Toxoplasma</i>-infected DC treated with GABAergic inhibitors.
Published 2012“…Color scales indicate photo emission (photons/s/cm<sup>2</sup>/sr) during a 180 s exposure. Data are from one set of mice and representative of two independent experiments with three to five mice per group. …”
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PI(3)P and VPS34 lipid kinase activity is decreased in <i>Becn1</i> deficient MEFs.
Published 2014“…Quantification of normalized <sup>32</sup>P-labelled PI(3)P from 3 separate experiments. Bars represent mean +/− s.e.m. (n = 3) con vs. def p<0.0001 using a one sample t-test (two-tailed). …”
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1358
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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1359
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1360
Decreased methylglyoxal-mediated protein glycation in the healthy aging mouse model of ectopic expression of UCP1 in skeletal muscle
Published 2023“…We found both young and aged HSA-mUCP1 mice had decreased advanced glycation endproducts (AGEs) formed from MG, lysine-derived Nε(1-carboxyethyl)lysine (CEL) and arginine-derived hydroimidazolone, MG-H1, whereas protein glycation by glucose forming Nε-fructosyl-lysine (FL) was increased ca. 2-fold, compared to wildtype controls. …”
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