Screening of either Higher Binding Affinity or Non-affinity scFv against Wild-type or Beta SARS-CoV-2. by Ye Yang (297214)

Image_2_Nrf2 Overexpression Decreases Vincristine Chemotherapy Sensitivity Through the PI3K-AKT Pathway in Adult B-Cell Acute Lymphoblastic Leukemia.tif by Li Wang (15202)

“…The nuclear factor erythroid 2-related factor 2 (Nrf2), a transcription factor, decreases apoptosis when its expression is upregulated. …”

eNOS-NO-induced small blood vessel relaxation requires EHD2-dependent caveolae stabilization by Claudia Matthaeus (7485782)

“…Concomitantly, impaired relaxation of mesenteric arteries and reduced running wheel activity were observed in EHD2 knockout mice. EHD2 deletion or knockdown led to decreased production of nitric oxide (NO) although eNOS expression levels were not changed. …”

Upregulation of miR-30a-5p resulted in promotion of glioblastoma cell growth that was reversed partially by Ad-S7. by Zhifan Jia (286723)

“…<p>(A) The figure showed that 30a-5p m increased the cell survival rate at a significantly higher rate in SNB19 cells and LN229 cells, (B) accelerated the glioma cells from G0/G1 to S phase in SNB19 cells and LN229 cells, (C) decreased the apoptotic cells in the 30a-5p m group, (D) promoted the cell invasive ability. …”

Dietary change improves weight gain, liver steatosis, glucose tolerance, and insulin resistance. by Mami Shiwa (712070)

Original images of HE staining, transmission electron microscopy, and fluorescence. by Cao Wang (1500691)

Subjects:

Animal phenotype raw data. by Cao Wang (1500691)

Subjects:

TOP2α/170 mRNA and protein levels in K562, drug resistant K/VP.5, and K562/SSedit-2 cells. by Victor A. Hernandez (12647320)

“…Using a two-tailed Student’s <i>t</i> test comparing the differences in mean calculated 2^-ΔCt values: <i>P</i> <0.001 for K/VP.5 vs. …”

OPJ: Origin data for Fig 5. by Nacer Badi (14046883)

“…Thermal and dynamic flow patterns are analyzed for a variety of parameters: Rayleigh numbers from 10² to 10⁶, PV panel tilt angle from 15° to 90°, and channel aspect ratios from 1/20 to 1/5. …”

IpgD enzymatic activity promotes the formation of infection foci by <i>S</i>. <i>flexneri</i> in HT-29 cells. by Volkan K. Köseoğlu (12055346)

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Structure-Based Design of a Chemical Probe Set for the 5‑HT_5A Serotonin Receptor by Anat Levit Kaplan (12126567)

“…Docking over 6 million molecules against a 5-HT_5AR homology model identified 5 mid-μM ligands, one of which was optimized to <b>UCSF678</b>, a 42 nM arrestin-biased partial agonist at the 5-HT_5AR with a more restricted off-target profile and decreased assay liabilities versus SB-699551. …”

Development of obesity, liver steatosis, glucose intolerance, and insulin resistance in high fat diet-fed mice. by Mami Shiwa (712070)

Hydrogen volume fraction distribution at different pressures (a) 1 MPa; (b) 3 MPa; (c) 5 MPa. by Weiqing Xu (1279959)

Reduced LFS-LTD but normal mGluR-LTD, HFS-LTP, TBS-LTP, and PSD density and morphology in the <i>Grin2b</i>^{<i>+/C456Y</i>} hippocampus. by Wangyong Shin (6793040)

Hierarchical clustering. by Monica E. Shapiro (22622240)

Hydrogen reduced AngII-induced susceptibility and duration of atrial fibrillation and improved atrial structure and blood pressure in AngII-induced rats. by Binmei Zhang (20529136)

Mean fMRI signal differences in the ROIs used in the online UG to predict acceptance vs. rejection for the five types of offers. by Maurice Hollmann (201868)

Macrophages play a role in esAEV-induced proliferation. by Safia A. Essien (20108379)

C5aR1 Mediates the Progression of Inflammatory Responses in the Brain of Rats in the Early Stage after Ischemia and Reperfusion by Yunwei Shi (10116568)

“…Further mechanism studies showed that inhibiting C5aR1 by PMX53 protected the rats from MCAO/R injury, decreased cell inflammation, and apoptosis via inhibiting the TLR4 and NF-κB signaling pathway and reducing the production of TNF-α, IL-1β, and IL-6 in MCAO/R rats. …”