Colocalization of Sig1R-YFP in SK-OV-3 cells with the markers pmKate2-mito and KDEL-mRFP. by Sergei Kopanchuk (6406085)

EDN3 is associated with decreased levels of RA receptor mRNA and RA metabolic enzyme mRNA. by Jonathan M. Gisser (456149)

Fomepizole treatment decreases the NAD(H) pool, impairs ATP production, and enhances ribosomal targeting antibiotic efficacy. by Hansol Im (14803255)

Effect of parasitism and PDV injection on triglyceride concentration and lipid metabolism-related gene expression in FAW larvae. by Xian Li (201841)

Neonatal oxygen exposure decreased elastin and increased collagen content in aortic media of 4 weeks-old rats. by Fanny Huyard (553968)

Effect of parasitism and PDV injection on lipid droplet size in the fat body of FAW larvae. by Xian Li (201841)

VEGF and sFlt-1 mutants exhibit changes in stem cell marker gene expression by RT-qPCR. by Christopher R. Schlieve (3179439)

“…<p>(A) VEGF mutants demonstrated 0.55-fold reduction in Lgr5 expression compared to littermates (*p = 0.04). …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Deciphering Nonbioavailable Substructures Improves the Bioavailability of Antidepressants by Serotonin Transporter by Zhi-Zheng Wang (6056033)

“…Here, we proposed the concept of “nonbioavailable substructures”, referring to substructures that are unfavorable to bioavailability. A machine learning model was developed to identify nonbioavailable substructures based on their molecular properties and shows the accuracy of 83.5%. …”

Video_3_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Image_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.TIF by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Video_1_Deficiency of TRIM32 Impairs Motor Function and Purkinje Cells in Mid-Aged Mice.AVI by Jian-Wei Zhu (285977)

“…In addition, deficiency of TRIM32 decreased Type I inositol 1,4,5-trisphosphate 5-phosphatase (INPP5A) levels in cerebellum. …”

Spontaneous beating rates in mESC-CMs. by Yukihiro Saito (797587)

Investigating the shared genetics of non-syndromic cleft lip/palate and facial morphology by Laurence J. Howe (5579186)

“…Where evidence was found of genetic overlap, we used bidirectional Mendelian randomization (MR) to test the hypothesis that genetic liability to nsCL/P is causally related to implicated facial phenotypes. Across 5,804 individuals of European ancestry from two studies, we found strong evidence, using PRS, of genetic overlap between nsCL/P and philtrum width; a 1 S.D. increase in nsCL/P PRS was associated with a 0.10 mm decrease in philtrum width (95% C.I. 0.054, 0.146; P = 2x10^-5). …”

shBRUCE-U2OS cell lines with expression of exogenous BRUCE variants. by Chunmin Ge (838812)

“…<p>(<b>A</b>) Diagram of a DOX-inducible shBRUCE construct under H1 promoter (tandem eight repeats of shBRUCE sequences, top) and five BRUCE constructs expressing wild type BRUCE, mutant BRUCE with BIR or UBC domain mutated at the active site as indicated by the respective number of amino acid residue, or with the entire domain deleted (Δ). …”

VEGF overexpression in OU culture increased OU size and altered stem/progenitor cell gene expression. by Christopher R. Schlieve (3179439)

“…(C) Significant increase in Bmi1 and Atoh1 expression and decrease in EphB2 expression was observed in doxycycline-treated VEGF OU compared to controls at 5 days (*p<0.05). …”

CK1δ-specific kinase activity in HT1080 cells is decreased after activation of Chk1. by Joachim Bischof (189845)