NLR family CARD domain containing 5 promotes hypoxia-induced cancer progress and carboplatin resistance by activating PI3K/AKT via carcinoembryonic antigen related cell adhesion mo... by Yu Dong (398252)

“…NLR family CARD domain containing 5 (NLRC5) is widely expressed in tissues and exerts a vital role in anti-tumor immunity. …”

Data_Sheet_1_Usability of the Video Head Impulse Test: Lessons From the Population-Based Prospective KORA Study.PDF by Maria Heuberger (551541)

“…</p><p>Results: Twenty-two of the 681 vHITs (3.2%) were not interpretable due to restrictive mistakes. …”

Data_Sheet_5_Relative supersaturation values distinguish between feline urinary and non-urinary foods and align with expected urine analytes contributions to uroliths.PDF by Elizabeth M. Morris (11143674)

S1 Dataset - by Edosa Tesfaye Geta (16541924)

“…SDM significantly decreased the level of HbA1c by 0.14% (95% CI = -0.28, -0.01, P = 0.00) when shared decisions were made in person or face-to-face at the point of care, but there was no statistically significant reduction in HbA1c levels when patients were engaged in online SDM. …”

RNA-seq transcriptional profiling of <i>Leishmania amazonensis</i> reveals an arginase-dependent gene expression regulation by Juliana Ide Aoki (3109917)

“…The absence of arginase activity in promastigotes increased the levels of pyrroline 5-carboxylate reductase, but decreased the levels of arginosuccinate synthase, pyrroline 5-carboxylate dehydrogenase, acetylornithine deacetylase and spermidine synthase transcripts levels. …”

DataSheet1_Effect of CYP3A4 Inhibitors and Inducers on Pharmacokinetics and Pharmacodynamics of Saxagliptin and Active Metabolite M2 in Humans Using Physiological-Based Pharmacokin... by Gang Li (34549)

“…The prediction results demonstrated that the oral dose of saxagliptin should be reduced to 2.5 mg when coadministrated with ketoconazole. The predictions also showed that although PK profiles of saxagliptin showed significant changes with delavirdine (AUC 1.5-fold increase) or rifampicin (AUC: a decrease to 0.19-fold) compared to those without inhibitors or inducers, occupancies of DPP-4 by saxagliptin were nearly unchanged, that is, the administration dose of saxagliptin need not adjust when there is coadministration with delavirdine or rifampicin.…”

E64 treatment reduced lesion size in RGAS053Δ<i>srv</i> infected mice but increased lesion size in MGAS315Δ<i>srv</i> infected mice. by Kristie L. Connolly (338016)

“…<p>The infecting dose (∼2×10⁸ CFU) of MGAS315, MGAS315Δ<i>srv,</i> RGAS053 or RGAS053Δ<i>srv</i> was resuspended in 333 µM E64 (0.1 ml), and 333 µM E64 (0.1 ml) was injected directly into the abscess each day following infection (n = 3 mice/strain). …”

MIB/MS kinome profiling reveals brigatinib target specificity in multiple <i>NF2</i>-deficient cell models. by Long-Sheng Chang (41691)

“…(H) HS11 and HS01 cells were treated with vehicle (DMSO) or brigatinib (1μM) for 24h prior to MIB/MS kinome profiling. MIB binding (log2LFQ intensities) was determined and the top 20 kinases with decreased MIB binding compared to vehicle are shown as a stacked bar plot for the two cell lines.…”

Trends in polypharmacy over 12 years and changes in its social gradients in South Korea by Yeon-Hee Baek (5759345)

“…Polypharmacy was defined as the concomitant prescription of ≥6 distinct medications on a single prescription at least once without a given duration. …”

Effects of the Central Lanthanide Ion Crystal Radius on the 15-MC_{Cu^II(N)pheHA}-5 Structure by Curtis M. Zaleski (1851952)

“…Each Ln^III[15-MC_CuII(N)pheHA-5]³⁺ complex is amphiphilic with a hydrophobic side consisting of the phenyl groups of the pheHA ligand and a side without the aromatic residues. …”

The salivary gland proteome of root-galling grape phylloxera (<i>Daktulosphaira vitifoliae</i> Fitch) feeding on <i>Vitis</i> spp. by Markus W. Eitle (8138322)

“…Quantitative RT-PCR analysis of five conserved effector candidates (protein disulfide-isomerase, peroxidoredoxin, peroxidase and a carboxypeptidase) revealed that their gene expression decreased, when larvae were starved for 24 h, supporting their assignment as effector molecules. …”

Synergistic interaction between <i>Brca2</i>^<i>G25R</i> mutation and <i>Palb2</i> heterozygosity. by Suzanne A. Hartford (596319)

“…<p><b>A.</b> Image of decreased body size in <i>B2</i>^<i>GR/Ko</i><i>;P2</i>^<i>Ko/+</i> animals (right) compared to littermate controls (left). …”

“Mixed” EPSP show characteristics of two types of EPSPs. by Haiyang Wei (346155)

HAI-2 deficiency disrupts normal architecture of intestinal epithelium. by Roman Szabo (138655)

“…Quantification of Alcian blue/PAS staining-positive cells in proximal (jejunum, left panel) and distal (ileum, middle panel) small intestine, and colon (right panel) at E18.5, P2, and P4. <i>Spint2</i>^{<i>−/−</i>}<i>;Prss8</i>^{<i>R44Q/R44Q</i>} mice present with a substantially decreased number of PAS-positive cells in both small and large intestines after birth. …”

Changes in expression of Kv7.5 and Kv7.2 channels in dorsal root ganglion neurons in the streptozotocin rat model of painful diabetic neuropathy by Laiche, Djouhri

“…We found 35 days post-STZ: (1) a significant decrease in Kv7.5-immunoreactivity in small (<30 μm) DRG neurons (both IB4 positive and IB4 negative) and medium-sized (30−40 μm) neurons, and (2) a significant increase in Kv7.2-immunoreactivity in small (<30 μm) neurons, and a non-significant increase in medium/large neurons. …”
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Data_Sheet_5_Unequal literacy development and access to online education in public versus private Panamanian schools during COVID-19 pandemic.PDF by Daniel Cubilla-Bonnetier (14578295)

Starvation reduces copper avoidance. by Molly A. Matty (6432926)

“…E) Animals are exposed to decreasing concentrations of diacetyl (DiA) (0.2%, 0.1% and 0.05%, or 1:200, 1:1000, and 1:2000, respectively) and other volatile attractants 0.1% Benzaldehyde (BZ) and 0.05% Isoamyl Alcohol (IAA). 50 mM CuSO₄ is the repellant in each condition N≥6. …”

Differential usage of splice sites in the <i>sf3b1</i> mutants. by Bei Zhang (428038)

S2 Fig - by Pierre Ganault (17972799)

Serum chemistry in the animals after chronic treatment with HIFN or vehicle. by Shweta Modgil (12864344)