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Protein arginine methyltransferase 5 (PRMT5) promotes survival of lymphoma cells via activation of WNT/B-catenin and AKT/GSK3B proliferative signaling
Published 2019“…We show that PRMT5 stimulates WNT/B-CATENIN signaling through direct epigenetic silencing of pathway antagonists, AXIN2 and WIF1, and indirect activation of AKT/GSK3 signaling.PRMT5 inhibition with either shRNA-mediated knockdown or a specific small molecule PRMT5 inhibitor, CMP-5, not only leads to derepression of WNT antagonists and decreased levels of active phospho-AKT (Thr-450 and Ser-473) and inactive phospho- GSK3B (Ser-9) but also results in decreased transcription of WNT/B-CATENIN target genes, CYCLIN D1, c-MYC, and SURVIVIN, and enhanced lymphoma cell death. …”
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Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel
Published 2019“…The electrochemical studies indicate that the corrosion rate of the steel samples coated with the epoxy modified with the healing additives decreases after 5 days of immersion in saline water.…”
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Multifunctional self-healing polymeric nanocomposite coatings for corrosion inhibition of steel
Published 2020“…The electrochemical studies indicate that the corrosion rate of the steel samples coated with the epoxy modified with the healing additives decreases after 5 days of immersion in saline water.…”
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Methylated pentavalent arsenic metabolites are bifunctional inducers, as they induce cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase through AhR- and Nrf2-dependent mechanis...
Published 2014“…Upon knockdown of AhR and Nrf2 the MMA(V)-, DMA(V)-, and TMA(V)-mediated induction of both CYP1A1 and NQO1 proteins was significantly decreased. …”
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Comprehensive thermoeconomic, exergoeconomic, and optimization analyses of direct oxy-combustion supercritical CO2 intercooled and reheated cycles under design and off-design condi...
Published 2022“…This study presents comprehensive energetic, exergetic, exergoeconomic, and economic (4E) performance analyses for four direct oxy-combustion (DOC) supercritical carbon dioxide (sCO2) power cycles at design, off-design, and part-load conditions. …”
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Development And Performance Evaluation Of Smart Polymeric Coatings For Corrosion Protection Of Steel
Published 2020“…Consequently, they are a promising solution for longer durability of coated piping steel and decreased operation expense. …”
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Corrosion behavior of API-X120 carbon steel alloy in a GTL F-T process water environment at low COD concentration
Published 2020“…The effect of temperature, time and rotation speed of FT-GTL process water on the corrosion rate of API X-120 carbon steel was investigated. Electrochemical impedance spectroscopy and potentiodynamic polarization techniques were used to determine the carbon steel corrosion rate under temperatures ranging from 293 to 323 K and rotation speed of 0, 500, 1000, 2000 rpm when the immersion time was 0.5, 1, and 2 h. …”
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Evidence of two mechanisms involved in Bacillus thuringiensis israelensis decreased toxicity against mosquito larvae: Genome dynamic and toxins stability
Published 2015“…This bacterium is characterized by a dynamic genome able to win or lose genetic materials which leads to a decrease in its effectiveness. …”
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Structural and magnetic properties of Ni1-xZnxFe 2O4 (x=0, 0.5 and 1) nanopowders prepared by sol-gel method
Published 2013“…A series of nanostructured Ni-Zn ferrites Ni1-xZn xFe2O4 (x=0, 0.5 and 1) with a grain size from 24 to 65 nm have been prepared with a sol-gel method. …”
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Investigation of solar PV performance under Doha weather using a customized measurement and monitoring system
Published 2016“…Results predict that the maximum power output from a Poly-crystalline panel decreases by around 30% for a dust exposure of five months. …”
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Simulation and experimental study of underwater dissimilar friction-stir welding between aluminium and steel
Published 2020“…473 and 573 K for the aluminum and steel sides, respectively) led to sub-stantial refining the grain structure and formation of a thinner IMC layer. …”
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Use and assessment of “e-plastics” as recycled aggregates in cement mortar
Published 2019“…The obtained results, for all RPs, (especially those of 7.5% and 10%) exhibited an increase in the CS of the specimens by 15.4% and 7.8%, respectively, with the MoE decreased in both cases by 18.1% and 23.8%, respectively. …”
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Two-stage cultivation of a Nannochloropsis mutant for biodiesel feedstock
Published 2015“…The fatty acid profile of MT-I5 also had an increased level of desirable saturated fatty acids (SFA) for use as a biodiesel feedstock, i.e. from 43 to 48�% of TFA, as well as a decreased level of less desirable polyunsaturated fatty acids (PUFA), i.e. from 22 to 7�% of TFA. …”
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L5 Spinal Nerve Axotomy Induces Distinct Electrophysiological Changes in Axotomized L5- and Adjacent L4-Dorsal Root Ganglion Neurons in Rats .
Published 2020“…Consistent with this hypothesis, we found (7 days post-SNA), in SNA rats with established pain hypersensitivity, slower AP kinetics in axotomized L5-neurons and faster AP kinetics in L4-nociceptive neurons including decreased rise time in Aδ-and Aβ-fiber nociceptors, and after-hyperpolarization duration in Aβ-fiber nociceptors. …”
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