Image_5_Multi-omics analysis of naïve B cells of patients harboring the C104R mutation in TACI.png by Neftali Ramirez (13251924)

Identifying the Basal Ganglia Network Model Markers for Medication-Induced Impulsivity in Parkinson's Disease Patients by Pragathi Priyadharsini Balasubramani (749707)

“…In the model, the BG action selection dynamics were mimicked using a utility function based decision making framework, with DA controlling reward prediction and 5HT controlling punishment and risk predictions. …”

Effect of Bcl-xL on proteins involved in the apoptotic pathway of MDCK cells. by Jiahao Zheng (807470)

DTG 3TC HIV EPI study.xlsx by Anna Esman (17983927)

“…Specifically, <i>CCR5</i> CpG 1 showed a significant increase in methylation from Week 0 to Week 48, while <i>CXCR4</i> CpG 3 displayed a significant decrease between Week 0 and Week 24. …”

Model parameters. by Maria Chironna (2268574)

“…<div><p>Global mitigation strategies to tackle the threat posed by SARS-CoV-2 have produced a significant decrease of the severity of 2020/21 seasonal influenza, which might result in a reduced population natural immunity for the upcoming 2021/22 influenza season. …”

Image_5_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…T cells and resident macrophages (rMP) were the largest populations in the normal cornea comprising 18.6 and 18.2 percent, respectively. rMP increased to 55.2% of cells after 5 days of DS. Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. …”

Data_Sheet_5_Gut microbiome changes in mouse, Mongolian gerbil, and hamster models following Clostridioides difficile challenge.PDF by Shuangshuang Wan (4014089)

Image_5_Single cell analysis of short-term dry eye induced changes in cornea immune cell populations.jpg by Jehan Alam (5577734)

“…T cells and resident macrophages (rMP) were the largest populations in the normal cornea comprising 18.6 and 18.2 percent, respectively. rMP increased to 55.2% of cells after 5 days of DS. Significant changes in expression of 1,365 genes (adj p < 0.0001) were noted in rMP with increases in cytokines and chemokines (Tnf, Cxcl1, Ccl12, Il1rn), inflammatory markers (Vcam, Adam17, Junb), the TAM receptor (Mertk), and decreases in complement and MHCII genes. …”

Hazardous Air Pollutants in Fresh and Aged Western US Wildfire Smoke and Implications for Long-Term Exposure by Katelyn O’Dell (6320639)

Comparison of Provean and non-synonymous results. by Quentin Rougemont (3249753)

“…In this study, we show that key evolutionary processes, including variations in <i>i</i>) effective population size (<i>N</i>_<i>e</i>) <i>ii</i>) recombination rates and <i>iii</i>) chromosome inheritance, have influenced the genetic load and efficacy of selection in Coho salmon (<i>Oncorhynchus kisutch</i>), a widely distributed salmonid species on the west coast of North America. …”

Relationship between GC3 and recombination. by Quentin Rougemont (3249753)

“…In this study, we show that key evolutionary processes, including variations in <i>i</i>) effective population size (<i>N</i>_<i>e</i>) <i>ii</i>) recombination rates and <i>iii</i>) chromosome inheritance, have influenced the genetic load and efficacy of selection in Coho salmon (<i>Oncorhynchus kisutch</i>), a widely distributed salmonid species on the west coast of North America. …”

PQ- or H₂O₂-mediated oxidative stress causes global metabolic changes. by Afzal Husain (131305)

“…<p>(<b>A–B</b>) Survival of <i>E. histolytica</i> trophozoites after 12 h of treatment with varying concentrations of PQ (<b>A</b>) or H₂O₂ (<b>B</b>). …”

Renal oxylipin profiles in WT and sEH-KO mice. by Ye Zhu (646531)

“…<p>(A): The conversion of linoleic acid-derived epoxides (EpOMEs) to the corresponding vicinal diols (DiHOMEs) was reduced in sEH-KO compared to WT mice as indicated by the decreased DiHOME/EpOME-ratios. …”

Plasma oxylipin profiles in WT and sEH-KO mice. by Ye Zhu (646531)

“…<p>(A): The conversion of linoleic acid-derived epoxides (EpOMEs) to the corresponding vicinal diols (DiHOMEs) was reduced in sEH-KO compared to WT mice as indicated by the decreased DiHOME/EpOME-ratios. …”

Image_5_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg by Chris Marco Mbianda Nana (14492776)

“…</p>Results<p>Placental Plasmodium falciparum infection was associated with significant increase in the frequency of total γδ T cells in IVBMC and of the Vδ1⁺ subset in PBMC and IVBMC, but decreased frequency of the Vδ2⁺ subset in PBMC and IVBMC. …”

Image_5_Phenotypic changes of γδ T cells in Plasmodium falciparum placental malaria and pregnancy outcomes in women at delivery in Cameroon.jpeg by Chris Marco Mbianda Nana (14492776)

“…</p>Results<p>Placental Plasmodium falciparum infection was associated with significant increase in the frequency of total γδ T cells in IVBMC and of the Vδ1⁺ subset in PBMC and IVBMC, but decreased frequency of the Vδ2⁺ subset in PBMC and IVBMC. …”

Image_5_Organelle Crosstalk Regulators Are Regulated in Diseases, Tumors, and Regulatory T Cells: Novel Classification of Organelle Crosstalk Regulators.tif by Ming Liu (105953)

“…Similarly, sepsis and trauma plus organ failures upregulated seven OCRG groups including vesicle, MT fission, mitophagy, sarcoplasmic reticulum–MT, MT fusion, autophagosome–lysosome fusion, and autophagosome/endosome–lysosome fusion, classified as the cell failure-handling OCRGs; (3) suppression of autophagosome–lysosome fusion in endothelial and epithelial cells is required for viral replications, which classify this decreased group as the viral replication-suppressed OCRGs; (4) pro-atherogenic damage-associated molecular patterns (DAMPs) such as oxidized low-density lipoprotein (oxLDL), lipopolysaccharide (LPS), oxidized-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (oxPAPC), and interferons (IFNs) totally upregulated 33 OCRGs in endothelial cells (ECs) including vesicle, MT fission, mitophagy, MT fusion, endoplasmic reticulum (ER)–MT contact, ER– plasma membrane (PM) junction, autophagosome/endosome–lysosome fusion, sarcoplasmic reticulum–MT, autophagosome–endosome/lysosome fusion, and ER–Golgi complex (GC) interaction as the 10 EC-activation/inflammation-promoting OCRG groups; (5) the expression of OCRGs is upregulated more than downregulated in regulatory T cells (Tregs) from the lymph nodes, spleen, peripheral blood, intestine, and brown adipose tissue in comparison with that of CD4⁺CD25⁻ T effector controls; (6) toll-like receptors (TLRs), reactive oxygen species (ROS) regulator nuclear factor erythroid 2-related factor 2 (Nrf2), and inflammasome-activated regulator caspase-1 regulated the expressions of OCRGs in diseases, virus-infected cells, and pro-atherogenic DAMP-treated ECs; (7) OCRG expressions are significantly modulated in all the 28 cancer datasets, and the upregulated OCRGs are correlated with tumor immune infiltrates in some tumors; (8) tumor promoter factor IKK2 and tumor suppressor Tp53 significantly modulate the expressions of OCRGs. …”

Two bortezomib injections do not improve muscle morphology, reduce fibrosis or increase body weight in <i>dy</i>^<i>2J</i><i>/dy</i>^<i>2J</i> mice. by Zandra Körner (843029)

“…(C) Bortezomib did not decrease the tenascin-C positive area in quadriceps muscle <i>dy</i>^<i>2J</i><i>/dy</i>^<i>2J</i> animals. …”

Global glomerulosclerosis proportions predict nephropathy progression in IgA nephropathy: a multicenter retrospective analysis with propensity score matching by Wenli Zou (1643875)

“…</p> <p>Based on the median of GS proportion, patients were divided into two groups (GS1 and GS2). Thereafter, the clinical, demographic, and treatment characteristics were evaluated by propensity score matching, Kaplan-Meier survival curves, Cox regression analyses. …”

RhoA controls retinoid signaling by ROCK dependent regulation of retinol metabolism by Alberto García-Mariscal (5644820)