Video_2_Effects of Antiepileptic Drugs on Spontaneous Recurrent Seizures in a Novel Model of Extended Hippocampal Kindling in Mice.MP4 by Hongmei Song (1639081)

“…Phenytoin (25 mg/kg) and levetiracetam (400 mg/kg) abolished the spontaneous recurrent seizures. Lorazepam (1.5 mg/kg) decreased motor seizure severity but did not reduce the incidence and duration of corresponding hippocampal discharges, implicating its inhibitory effects on seizure spread. …”

Table_2_The plasma lipids with different fatty acid chains are associated with the risk of hemorrhagic stroke: a Mendelian randomization study.DOCX by Xingkai Zhang (18065716)

“…Notably, lipids containing arachidonic acid chains (C20:4) such as PC 18:1;0_20:4;0 consistently showed a decreased risk of both intracerebral hemorrhage [p < 0.001; OR(95% CI) = 0.892(0.835–0.954)] and subarachnoid hemorrhage [p = 0.002; OR(95% CI) = 0.794(0.689–0.916)]. …”

Video_1_Effects of Antiepileptic Drugs on Spontaneous Recurrent Seizures in a Novel Model of Extended Hippocampal Kindling in Mice.MP4 by Hongmei Song (1639081)

“…Phenytoin (25 mg/kg) and levetiracetam (400 mg/kg) abolished the spontaneous recurrent seizures. Lorazepam (1.5 mg/kg) decreased motor seizure severity but did not reduce the incidence and duration of corresponding hippocampal discharges, implicating its inhibitory effects on seizure spread. …”

Table1_Effects of the Full Coverage Policy of Essential Medicines on Inequality in Medication Adherence: A Longitudinal Study in Taizhou, China.DOCX by Zhigang Guo (727834)

“…The proportion of patients with high adherence increased from 39.9% at baseline to 51.6, 57.2, and 60.5%, while CI decreased from 0.073 to −0.011, −0.029, and −0.035. …”

Table_1_Altered Lipid Profile Is a Risk Factor for the Poor Progression of COVID-19: From Two Retrospective Cohorts.doc by Hui Jin (38113)

“…</p>Conclusions<p>The baseline dyslipidemia should be considered as a risk factor for poor prognosis of COVID-19. However, lipid levels may be altered during the COVID-19 course, since lipidology may be distinctly affected by both inflammation and organic damage for SARS-CoV-2.…”

Table_1_The neuroelectrophysiological and behavioral effects of transcranial direct current stimulation on executive vigilance under a continuous monotonous condition.DOCX by Jing Dai (470985)

“…Participants completed four sessions of vigilance task and five sessions of self-report sleepiness, Oddball task, and Go/Nogo task, for a total of about 5 h. …”

Data Sheet 1_The prevalence, pathophysiology, and treatment of fecal incontinence in patients with Crohn’s disease: a systematic review and meta-analysis.zip by Yuting Shi (491528)

“…</p>Results<p>In this analysis, a total of 25 studies were included. Fifteen of these studies assessed the prevalence of FI among 7232 patients with CD, yielding a pooled estimated prevalence of 34.8% (95% CI: 24.0%–46.5%). …”

Table_1_Sex-Related Differences in Lactotroph Tumor Aggressiveness Are Associated With a Specific Gene-Expression Signature and Genome Instability.XLSX by Anne Wierinckx (164065)

“…Hundred-forty genes showed an increased or decreased expression with a minimum 2-fold change. …”

DataSheet1_Efficacy of moxibustion in diarrhea-predominant irritable bowel syndrome model rats: a systematic review and meta-analysis.PDF by Xiang Rao (17640756)

“…The meta-analysis results demonstrated that moxibustion enhanced the threshold capacity of the abdominal withdrawal reflex (AWR) [standardized mean difference (SMD) = 1.84; 95% confidence interval (CI): 1.09, 2.60; p < 0.00001], ameliorated the rate of loose stool (SMD = −4.03; 95% CI: –5.76, −2.30; p < 0.00001), and decreased the colon 5-hydroxytryptamine (SMD = −3.67; 95% CI: –5.33, −2.01; p < 0.00001), serum interleukin-1β (SMD = −3.24, 95% CI: –4.06, −2.41; p < 0.00001), serum tumor necrosis factor-α (SMD = −2.35, 95% CI: –4.12, −0.58; p < 0.00001), and serum substance P (SMD = −5.14, 95% CI: –8.45, −1.83; p = 0.002) concentrations. …”

S1 File - by Phyo Zin Winn (16733843)

“…PubMed (Public/Publisher MEDLINE), PubMed Central and EMBASE (Excerpta Medica Database) databases were conveniently selected and Boolean search commands were used for a comprehensive literature search. Five core search terms were "effects of treatments", " COVID-19-related olfactory dysfunction", "corticosteroids", "treatments" and "interventions". …”

Psychological and Educational Intervention to Improve Tuberculosis Treatment Adherence in Ethiopia Based on Health Belief Model: A Cluster Randomized Control Trial by Habteyes Hailu Tola (2742364)

“…However, after intervention, non-adherence level decreased among intervention group from 19.4 (at baseline) to 9.5% (at endpoint), while it increased among control group from 19.4% (baseline) to 25.4% (endpoint). …”

Association between XRCC1 and XRCC3 Polymorphisms with Lung Cancer Risk: A Meta-Analysis from Case-Control Studies by Guohua Huang (450184)

“…<div><p>Many studies have reported the association of X-ray repair cross-complementing group 1 (<i>XRCC1</i>) Arg399Gln, Arg194Trp, Arg280His, −77T>C, and X-ray repair cross-complementing group 3 (<i>XRCC3</i>) T241M polymorphisms with lung cancer risk, but the results remained controversial. Hence, we performed a meta-analysis to investigate the association between lung cancer risk and <i>XRCC1</i> Arg399Gln (14,156 cases and 16,667 controls from 41 studies), Arg194Trp (7,426 cases and 9,603 controls from 23 studies), Arg280His (6,211 cases and 6,763 controls from 16 studies), −77T>C (2,487 cases and 2,576 controls from 5 studies), and <i>XRCC3</i> T241M (8,560 cases and 11,557 controls from 19 studies) in different inheritance models. …”

Data_Sheet_1_Association between dried fruit intake and pan-cancers incidence risk: A two-sample Mendelian randomization study.docx by Chen Jin (703369)

“…</p>Results<p>The evidence from IVW analyses showed that each increase of dried fruit intake by one standard deviation was statistically significantly associated with 82.68% decrease of oral cavity/pharyngeal cancer incidence risk (P = 0.0131), 67.01% decrease of lung cancer incidence risk (P = 0.0011), 77% decrease of squamous cell lung cancer incidence risk (P = 0.0026), 53.07% decrease of breast cancer incidence risk (P = 4.62 × 10^–5), 39.72% decrease of ovarian cancer incidence risk (P = 0.0183), 97.26% decrease of pancreatic cancer incidence risk (P = 0.0280), 0.53% decrease of cervical cancer incidence risk (P = 0.0482); however, there was no significant effect on lung adenocarcinoma (P = 0.4343), endometrial cancer (P = 0.8742), thyroid cancer (P = 0.6352), prostate cancer (P = 0.5354), bladder cancer (P = 0.8996), and brain cancer (P = 0.8164). …”

S1_raw_images. by Lijun Mao (561880)

“…Mechanism investigations revealed that miR-122 directly suppressed the expression of RBM47, which was a novel RNA binding protein. RBM47 decreased the level of α_v integrin (ITGAV) by promoting the degradation of mRNA via interacting with the AU-rich elements in its 3’UTR. …”

Raw data for graphs. by Lijun Mao (561880)

“…Mechanism investigations revealed that miR-122 directly suppressed the expression of RBM47, which was a novel RNA binding protein. RBM47 decreased the level of α_v integrin (ITGAV) by promoting the degradation of mRNA via interacting with the AU-rich elements in its 3’UTR. …”

The predicted AREs in the 3’UTR of ITGAV mRNA. by Lijun Mao (561880)

“…Mechanism investigations revealed that miR-122 directly suppressed the expression of RBM47, which was a novel RNA binding protein. RBM47 decreased the level of α_v integrin (ITGAV) by promoting the degradation of mRNA via interacting with the AU-rich elements in its 3’UTR. …”

Characteristics of the included studies. by Phyo Zin Winn (16733843)

“…PubMed (Public/Publisher MEDLINE), PubMed Central and EMBASE (Excerpta Medica Database) databases were conveniently selected and Boolean search commands were used for a comprehensive literature search. Five core search terms were "effects of treatments", " COVID-19-related olfactory dysfunction", "corticosteroids", "treatments" and "interventions". …”

The frame of review question. by Phyo Zin Winn (16733843)

“…PubMed (Public/Publisher MEDLINE), PubMed Central and EMBASE (Excerpta Medica Database) databases were conveniently selected and Boolean search commands were used for a comprehensive literature search. Five core search terms were "effects of treatments", " COVID-19-related olfactory dysfunction", "corticosteroids", "treatments" and "interventions". …”

Supplementary Material for: Diffusion Tensor Imaging Reveals Whole-Brain Microstructural Changes in the P301L Mouse Model of Tauopathy by Massalimova A. (10780776)

“…Using high-resolution ex vivo diffusion tensor imaging (DTI), we investigated microstructural changes in the white and grey matter in the P301L mouse model of human tauopathy at 8.5 months of age. For unbiased computational analysis, we implemented a pipeline for voxel-based analysis (VBA) and atlas-based analysis (ABA) of DTI mouse brain data. …”

S3 Fig - by Maryam Banar (3220221)