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64761
Differential effects of selective and non-selective cyclooxygenase inhibitors on fecal microbiota in adult horses
Published 2018“…Therefore, our objectives were to determine whether the composition and diversity of the fecal microbiota of adult horses were altered by NSAID use, and whether these effects differed between non–selective and COX-2-selective NSAIDs. Twenty-five adult horses were randomly assigned to 1 of 3 groups: control (n = 5); phenylbutazone (n = 10); or, firocoxib (n = 10). …”
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64762
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64763
Applying Corrigan’s progressive model of self-stigma to people with depression
Published 2019“…The aim of this study was to test the progressive model of self-stigma in three respects: I) successive stages have the strongest associations, II) endorsements decrease with each stage, and III) the procedural character can be represented by one serial mediation model.…”
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64764
Data Sheet 1_Role of memantine in adult migraine: a systematic review and network meta-analysis to compare memantine with existing migraine preventive medications.docx
Published 2024“…Our analysis showed that memantine demonstrated the second-largest reduction in migraine days [standardized mean difference (SMD): −0.83; 95% confidence interval (CI): −1.26, −0.41 compared with placebo] and the highest 50% response rates [odds ratio (OR): 5.58, 95% CI: 1.31 to 23.69] in all studied interventions. …”
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64765
A Personalized short-time Immunotherapy with Subcutaneous very low-dose Il-2 plus the Pineal Hormone Melatonin in advanced cancer patients with Persistent Lymphocytopenia
Published 2021“…Finally, it is known that lymphocytopenia may predict a negative prognosis in the advanced neoplasms, and a more negative significance is played by the occurrence of abnormally low values of lymphocyte-to-monocyte ratio (LMR), whose decline could depend on both lymphocyte decrease and monocyte increase. …”
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64766
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64767
Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF
Published 2023“…Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”
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64768
Image_2_Human Wharton's Jelly Stem Cell (hWJSC) Extracts Inhibit Ovarian Cancer Cell Lines OVCAR3 and SKOV3 in vitro by Inducing Cell Cycle Arrest and Apoptosis.TIF
Published 2018“…Real-time gene expression analysis of OVCAR3 and SKOV3 treated with hWJSC-CM (50%) or hWJSC-CL (15 μg/ml) for 48 h demonstrated decreased expression of cell cycle regulatory genes (cyclin A2, Cyclin E1), prostaglandin receptor signaling genes (EP2, EP4) and the pro-inflmmatory genes (IL-6, TNF-α) compared to untreated controls. …”
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64769
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64770
Data fo "<strong>ENSO skewness hysteresis and associated changes in strong El Niño under a CO2 removal scenario</strong>"
Published 2023“…The CO2 ramp-up and ramp-down experiment branches from the PD experiment at different phases of the Pacific Decadal Oscillation and Atlantic Multidecadal Oscillation to generate a total of 28 ensemble members. Each member is forced by the same time-varying CO2 forcing for 500 years, comprising a 1% increase per year in the CO2 concentration for 140 years until the concentration quadrupled (4×CO2, 1,468 p.p.m.v., ramp-up period); and a subsequent symmetric 1% decrease per year in CO2 concentration for another 140 years until it returned to the initial level (1×CO2, 367 p.p.m.v., ramp-down period), and a fixed CO2 concentration for the remaining 220 years (1×CO2, 367 p.p.m.v., restoring period). …”
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64771
Image_1_High Circulating Methylated DNA Is a Negative Predictive and Prognostic Marker in Metastatic Colorectal Cancer Patients Treated With Regorafenib.pdf
Published 2019“…In addition, high cmDNA/ml values during regorafenib treatment predicted with higher accuracy shorter PFS (<16 weeks with a PPV of 96%), therefore associated with increased risk of progression (HR for progression = 2.985; [95%CI: 1.63–5.46; p < 0.0001).…”
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64772
Table_1_High Circulating Methylated DNA Is a Negative Predictive and Prognostic Marker in Metastatic Colorectal Cancer Patients Treated With Regorafenib.pdf
Published 2019“…In addition, high cmDNA/ml values during regorafenib treatment predicted with higher accuracy shorter PFS (<16 weeks with a PPV of 96%), therefore associated with increased risk of progression (HR for progression = 2.985; [95%CI: 1.63–5.46; p < 0.0001).…”
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64773
Nucleotide excision repair pathway assessment in DNA exposed to low-intensity red and infrared lasers
Published 2019“…Also, plasmid DNA was exposed to laser light to study DNA lesions produced in vitro by T4endonuclease V. Low-intensity lasers: i) had no effect on survival of wild-type E. coli but decreased the survival of uvrA protein-deficient cells, ii) induced bacterial filamentation, iii) did not alter the electrophoretic profile of plasmids in agarose gels, and iv) did not alter the electrophoretic profile of plasmids incubated with T4 endonuclease V. …”
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64774
Table2_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx
Published 2024“…SNHG9 knockdown resulted in a significant increase in G1 phase cells and a decrease in S and G2 phases, indicating inhibition of DNA synthesis and cell cycle progression. …”
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64775
Table1_Cuproptosis-related lncRNAs emerge as a novel signature for predicting prognosis in prostate carcinoma and functional experimental validation.docx
Published 2024“…SNHG9 knockdown resulted in a significant increase in G1 phase cells and a decrease in S and G2 phases, indicating inhibition of DNA synthesis and cell cycle progression. …”
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64776
datasheet1_Biochar-Swine Manure Impact on Soil Nutrients and Carbon Under Controlled Leaching Experiment Using a Midwestern Mollisols.docx
Published 2021“…Three biochars 1) neutral pH red-oak (RO), 2) highly alkaline autothermal corn (Zea mays) stover (HAP), and 3) mild acidic Fe-treated autothermal corn stover (HAPE) were incubated with swine manure for a month. The biochar-manure mixture was applied in triplicate to soil columns with an application rate determined by the P<sub>2</sub>O<sub>5</sub>-P content in manure or manure-biochar mixtures after the incubation. …”
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64777
Fig 1 -
Published 2022“…(E) Cell cycle assay by FACS showed that DOX significantly decreased the proportion of cells in the G1 phase and increased those in the G2 phase of the cell cycle (unpaired t-test, n = 6, *** <i>p</i> < 0.001, ** <i>p</i> < 0.01, NS: no significant difference). …”
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64778
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64779
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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64780
Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19·1 million participants
Published 2017“…Global age-standardised prevalence of raised blood pressure was 24·1% (21·4–27·1) in men and 20·1% (17·8–22·5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. …”
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