Effect of low cross-linked matrices on osteoblast and osteoclast. by Takako Ida (5787254)

“…(d) Alkaline phosphatase (ALP) activity increased in cells seeded on low cross-linked matrices. (e) Gene expression of <i>Cbfa1/Runx2</i>, type I collagen α2 chain (<i>Col1a2</i>), alkaline phosphatase (<i>Alpl</i>), and osteocalcin (<i>Spp1</i>) significantly increased in these matrices at 3 and 7 days of culture. …”

Supplementary file 1_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.pdf by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

The optimal pulse shape depends on the shape of the nonlinearity. by Patrick A. Fletcher (583336)

“…The production rate function is F(A) = A². (<b>E</b>) Sigmoidal production rate functions give rise to bell-shaped response. …”

Data_Sheet_1_Aspergillus niger Spores Are Highly Resistant to Space Radiation.PDF by Marta Cortesão (6398336)

“…In all strains, UV-C treated spores (1000 J/m²) were shown to have decreased biofilm formation (81% reduction in wild-type spores). …”

Table 1_Cross-education: motor unit adaptations mediate the strength increase in non-trained muscles following 8 weeks of unilateral resistance training.xlsx by Edoardo Lecce (20518145)

“…These gains were accompanied by significant decreases in motor unit recruitment thresholds (p < 0.01) and higher net discharge rate (i.e., gain in discharge rate from recruitment to peak) following intervention (p < 0.05). …”

Increased TMJ Osteoarthritis-like characteristics in <i>Prg4</i>⁻^<i>/</i>− mice. by Adele Hill (298189)

“…Insets in C and D correspond to a magnification of the field indicated in the red dotted line and highlight the extracellular localization of aggrecan neopeptide staining (arrows). (<b>E–J</b>) TRAP staining in 2-, 6- and 9- month TMJ sections. …”

Spontaneous replay switches between multiple environments. by Bastian Pietras (14295598)

“…In the meso- and microscopic models, transitions from environment <i>k</i> to <i>j</i> are equally likely for all pairs (<i>k</i>, <i>j</i>) ∈ {1, 2, 3}². But the deterministic (macro and RT) models show a clear preference for transitions 1 → 3 → 2 → 1, which is also apparent in the high probability of the corresponding subsequences of three distinct, subsequently active environments. …”

DataSheet1_Agmatine Alleviates Epileptic Seizures and Hippocampal Neuronal Damage by Inhibiting Gasdermin D-Mediated Pyroptosis.PDF by Xueying Li (449429)

“…H&E and Nissl staining were used to evaluate hippocampal neuronal damage. …”

Phenotypic characterization of mice. by Troy Perry (4442725)

“…#p<0.05 compared with Ct and Sh. (E) 16s gene copy number in terminal ileum. There was a significant increase in bacterial load in the ICR groups by day 31 (Group 2 –late DSS). * p≤0.05 relative to Ct and Sh.…”

DataSheet_1_Systematic Investigation of the Efficacy of Sinitang Decoction Against Ulcerative Colitis.docx by Enhui Ji (9325940)

“…Additionally, SNT reversed the upregulated levels of serum tumor necrosis factor (TNF)-α, prostaglandin E₂ (PGE₂), interleukin (IL)-6, and nitric oxide (NO) in UC model rats. …”

Table_1_Predicting Disease Progression and Mortality in Aortic Stenosis: A Systematic Review of Imaging Biomarkers and Meta-Analysis.docx by Alain Nchimi (798171)

Data Sheet 9_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Image_4_Case Report: Severe McCune–Albright syndrome presenting with neonatal Cushing syndrome: navigating through clinical obstacles.pdf by Yagmur Unsal (16644225)

Data Sheet 6_Lathyrol inhibits the proliferation of Renca cells by altering expression of TGF-β/Smad pathway components and subsequently affecting the cell cycle.xlsx by Shengyou Song (22391068)

“…In vivo, lathyrol suppressed the mRNA and protein expression of TGF-β1, TGF-βR1, Smad2, Smad3, Smad4, and Smad9 in RCC xenografts; promoted the protein expression of Smad6; and decreased the protein expression of cyclin D1, cyclin B1, cyclin A1, cyclin E1, CDK6, CDK4, and CDK1 while increasing the expression of P16, P21, and P27.…”

Table_3_Effects of Dietary Fatty Acids on Bovine Oocyte Competence and Granulosa Cells.DOCX by Arpna Sharma (5600399)

“…ALA and cis-9, trans-11 CLA significantly down-regulated the expression of STAR, CYP19A1, FSHR, LHCGR and decreased the 17β-Estradiol (E2) and progesterone (P4) production. …”

Table 1_Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework.docx by Rajamohanan Pillai Ranith (22589207)

A Majority of Human Melanoma Cell Lines Exhibits an S Phase-Specific Defect in Excision of UV-Induced DNA Photoproducts by François Bélanger (21876)

“…In addition, melanoma strains deficient in S phase-specific DNA photoproduct removal manifest significantly lower levels of phosphorylated histone H2AX at 1 h post-UV, suggesting diminished activation of ataxia telangiectasia and Rad 3-related (ATR) kinase, i.e., a primary orchestrator of the cellular response to UV-induced DNA replication stress. …”

Table_1_Effects of Dietary Fatty Acids on Bovine Oocyte Competence and Granulosa Cells.DOCX by Arpna Sharma (5600399)

“…ALA and cis-9, trans-11 CLA significantly down-regulated the expression of STAR, CYP19A1, FSHR, LHCGR and decreased the 17β-Estradiol (E2) and progesterone (P4) production. …”

Comparison between LEVs and SEVs of their different origins and compositions, and the inhibitory effect of different inhibitors on the release of virus in EVs by western blot. by Weining Wu (3355445)

“…<b>(C)</b> MTT cytotoxicity assay measures cytotoxic effect on BSR cells at the concentrations of GW4869 and EerI used. Two-way ANOVA test *<i><i>p</i></i> < 0.05. <b>(D)</b> The expression of sphingomyelin phosphodiesterase 2 (SMPD2), which is inhibited by GW4869 treatment, and (E) ubiquitinated proteins on EerI treatment were analyzed by western blot. …”

Kinome-Wide Functional Genomics Screen Reveals a Novel Mechanism of TNFα-Induced Nuclear Accumulation of the HIF-1α Transcription Factor in Cancer Cells by Angela Schoolmeesters (183679)

“…On the other hand, depletion of PRKAR2B, ADCK2, TRPM7, and TRIB2 significantly decreases the effect of TNFα on HIF-1α stability in osteosarcoma and prostate cancer cell lines. …”