Supplementary Material for: National Trends in Emergency Room Visits of Dialysis Patients for Adverse Drug Reactions by Chan L. (5371679)

“…<b><i>Results:</i></b> While ED visits for ADEs decreased in both groups, they were over 10-fold higher in dialysis patients than non-dialysis patients (65.8–88.5 per 1,000 patients vs. 4.6–5.4 per 1,000 patients respectively, <i>p</i> < 0.001). …”

Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid‑1 Receptor Antagonists for Metabolic Syndrome Disorders by Szabolcs Dvorácskó (14767447)

“…We have designed orally bioavailable, non-brain-penetrant antagonists of the cannabinoid-1 receptor (CB₁R) with a built-in biguanide sensor to mimic 5′-adenosine monophosphate kinase (AMPK) activation for treating obesity-associated co-morbidities. …”

Supplementary Material for: Clinical Impact of Early Tumour Shrinkage in Metastatic or Unresectable Oesophageal Cancer Treated with Pembrolizumab plus Chemotherapy by Sugase T. (2871863)

“…The median progression-free survival (PFS) and overall survival (OS) for ETS ≥20% and <20% were 12.7 and 5.5 months and 14.4 and 8.2 months, and 12.7 and 4.9 months and 14.4 and 8.0 months for DpR ≥30% and <30%, respectively. …”

Data_Sheet_1_Proliferation of Lung Epithelial Cells Is Regulated by the Mechanisms of Autophagy Upon Exposure of Soots.PDF by Rituraj Niranjan (11164974)

“…Exposure of fullerene soot protected the cell death of A549 cells, caused by hydrogen peroxide, and inhibited LPS-induced autophagy. …”

Table 4_Characteristics of pediatric interventional drug trials registered between 2015 and 2024 on ClinicalTrials.gov.docx by Yinghong Zhou (6873053)

“…Among these, 1,975 (67.5%) enrolled no more than 100 participants, and 153 (5.2%) were restricted to either males or females, with this gender-specific enrollment correlated with disease epidemiology. …”

DataSheet_1_Blocking autofluorescence in brain tissues affected by ischemic stroke, hemorrhagic stroke, or traumatic brain injury.zip by Shaoshuai Wang (720590)

“…Sudan black B (SBB) is a staining dye widely used in histological studies to eliminate autofluorescence. …”

Cannabinoformins: Designing Biguanide-Embedded, Orally Available, Peripherally Selective Cannabinoid‑1 Receptor Antagonists for Metabolic Syndrome Disorders by Szabolcs Dvorácskó (14767447)

“…We have designed orally bioavailable, non-brain-penetrant antagonists of the cannabinoid-1 receptor (CB₁R) with a built-in biguanide sensor to mimic 5′-adenosine monophosphate kinase (AMPK) activation for treating obesity-associated co-morbidities. …”

Image_2_Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway.JPEG by Xiu-ying Luo (10984614)

“…The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly, a MI mouse model was established by coronary artery ligation, which was then treated with different concentrations of TMZ (5, 10, and 20 mg kg^–1 day^–1). …”

Table_1_Microbial community succession in the intestine of mice with deep partial-thickness burns.DOCX by Li-Jian Chen (3356018)

“…On day 28 after the burn, the microbiome composition largely returned to the pre-burn level, although day 5 was a turning point for change. Some probiotics, such as the Lachnospiraceae_NK4A136_group, decreased in composition after the burn but were restored in the later recovery period. …”

Image 4_Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis.tif by Tao Sun (91038)

“…Introduction<p>The Th2 immune response plays a pivotal role in the pathogenesis of schistosomiasis, contributing to the formation of hepatic granulomas and fibrosis. …”

Table_3_Dietary Corn Bran Altered the Diversity of Microbial Communities and Cytokine Production in Weaned Pigs.docx by Ping Liu (156158)

“…On day 28, piglets fed dietary CB had a higher shannon index (P < 0.05). The population of the Firmicutes in CB treatment were decreased (P < 0.05), while the percentage of the Bacteroidetes were increased (P < 0.05). …”

Image_6_Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway.JPEG by Xiu-ying Luo (10984614)

“…The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly, a MI mouse model was established by coronary artery ligation, which was then treated with different concentrations of TMZ (5, 10, and 20 mg kg^–1 day^–1). …”

Data_Sheet_1_Indirect regulation of topsoil nutrient cycling by groundwater depth: impacts on sand-fixing vegetation and rhizosphere bacterial communities.docx by Lianyi Hao (17559537)

“…</p>Results<p>The four plant growth indices (Pielou, Margalef, Simpson, and Shannon-Wiener indices) and soil water content (SWC) at the Artem and Salix sites all showed a decreasing trend with increasing GTD. Salix had a higher nutrient content than Artem. …”

Data_Sheet_1_Late-Season Nitrogen Applications Increase Soybean Yield and Seed Protein Concentration.docx by Anuj Chiluwal (6633080)

“…The results showed that cover crops had a negative effect on yield in two out of six site-years and decreased seed protein concentration by 8.2 mg g⁻¹ on average in Minnesota. …”

Table 2_Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis.docx by Tao Sun (91038)

“…Introduction<p>The Th2 immune response plays a pivotal role in the pathogenesis of schistosomiasis, contributing to the formation of hepatic granulomas and fibrosis. …”

Changes in cervical immunity from before to after acquisition of cervicovaginal infections (CVIs) stratified by hormonal contraceptive use (no HC, DMPA and COC) and adjusted for si... by Raina N. Fichorova (7251227)

“…<p>CVIs include: (1) vaginal dysbiosis defined by Nugent 4–6, Nugent 7–10 or a positive test for candida, and (2) sexually transmitted infections positive for <i>Chlamydia trachomatis</i> (CT), <i>Neisseria gonorrhoeae</i> (NG), <i>Trichomonas vaginalis</i> (TV) or genital herpes (HSV-2). …”

Data_Sheet_1_Morel (Morchella spp.) intake alters gut microbial community and short-chain fatty acid profiles in mice.docx by Longying Pei (17024469)

“…Healthy mice were randomly assigned to five groups: a control group (0% morel) and four intervention groups supplemented with different levels of morel mushrooms (5% for M5, 10% for M10, 15% for M15, and 20% for M20) over a period of 4 weeks. …”

Supplementary file 1_Model-based multi-year P flow analyses and strategies for sustainable food chain management in Changzhou city at China's Taihu Basin.docx by Zheng Guo (14989)

“…This study employed the substance flow analysis (SFA) method to construct a P flow model for the food chain in Changzhou, a representative lakeside city in the Taihu Basin. …”

Image_15_Function and Mechanism of Trimetazidine in Myocardial Infarction-Induced Myocardial Energy Metabolism Disorder Through the SIRT1–AMPK Pathway.JPEG by Xiu-ying Luo (10984614)

“…The current study set out to evaluate the effect and mechanism of TMZ on MEM disorder induced by myocardial infarction (MI). Firstly, a MI mouse model was established by coronary artery ligation, which was then treated with different concentrations of TMZ (5, 10, and 20 mg kg^–1 day^–1). …”

Image 2_Glucocorticoid receptor inhibits Th2 immune responses by down-regulating Pparg and Gata3 in schistosomiasis.tif by Tao Sun (91038)

“…Introduction<p>The Th2 immune response plays a pivotal role in the pathogenesis of schistosomiasis, contributing to the formation of hepatic granulomas and fibrosis. …”