Disruption of <em>Yarrowia lipolytica TPS1</em> Gene Encoding Trehalose-6-P Synthase Does Not Affect Growth in Glucose but Impairs Growth at High Temperature by Carmen-Lisset Flores (206091)

“…Trehalose content was below 1 nmol/mg dry weight in <em>Y. lipolytica</em>, but it increased in strains expressing <em>YlTPS1</em> under the control of the <em>YlTEF1</em>promoter or with a disruption of YALI0D15598 encoding a putative trehalase. mRNA levels of <em>YlTPS1</em> were low and did not respond to thermal stresses, but that of <em>YlTPS2</em> (YALI0D14476) and <em>YlTPS3</em> (YALI0E31086) increased 4 and 6 times, repectively, by heat treatment. …”

Table 1_Ambroxol attenuates detrimental effect of LPS-induced glia-mediated neuroinflammation, oxidative stress, and cognitive dysfunction in mice brain.xlsx by Safi Ullah (18598897)

“…Among various factors, lipopolysaccharides (LPSs) from Gram-negative bacteria, such as E. coli, are considered potential causative agents. …”

Data_Sheet_1_TRIM18-Regulated STAT3 Signaling Pathway via PTP1B Promotes Renal Epithelial–Mesenchymal Transition, Inflammation, and Fibrosis in Diabetic Kidney Disease.docx by Qi Chen (144168)

“…TRIM18 knockdown inhibits high glucose (HG)-induced epithelial–mesenchymal transition (EMT), inflammation, and fibrosis of HK-2 cells. This is accompanied by decreased levels of tumor necrosis factor alpha, interleukin-6, hydroxyproline (Hyp), connective tissue growth factor, and α-smooth muscle actin. …”

Phenotypic alterations caused by the interruption of <i>ter1</i> in <i>U</i>. <i>maydis</i>. by Juan Antonio Sanpedro-Luna (14833497)

“…(B) Serial 10-fold dilutions of cultures were spotted on YEPS or MC plates and incubated for 2 days at 28°C; ter1 mutants showed dramatic decreases in colony formation and colony size, consistent with the loss of telomerase activity described in other organisms. …”

Data_Sheet_1_Comparison of the Metabolic Profiles in the Plasma and Urine Samples Between Autistic and Typically Developing Boys: A Preliminary Study.PDF by Xin-Jie Xu (462961)

Data_Sheet_1_L-Canavanine, a Root Exudate From Hairy Vetch (Vicia villosa) Drastically Affecting the Soil Microbial Community and Metabolite Pathways.PDF by Hossein Mardani-Korrani (8483940)

“…Prediction of the soil metabolic pathways using PICRUSt2 estimated that the L-arginine degradation pathway was enriched 1.3-fold when L-canavanine was added to the soil. …”

Biotransformation capacity. by Semjon Seemann (796546)

“…<p>Benzyloxyresorufin-O-debenzylation [BROD] (A), ethoxyresorufin-O-deethylation [EROD] (B), ethylmorphine-N-demethylation [EMND] (C) and glutathione-S-transferase (D, as 1-chloro-2,4-dinitrobenzene conjugation) activities in 9000g supernatants are shown exemplarily. …”

Data_Sheet_1_Sex-Differences in Aortic Stenosis: Mechanistic Insights and Clinical Implications.pdf by Lara Matilla (5270021)

“…</p>Approach and Results<p>238 patients with severe AS undergoing surgical valve replacement were recruited. Two hundred and two AVs (39.1% women) were used for ex vivo analyses and 36 AVs (33.3% women) for in vitro experiments. …”

Image_3_Dynamics of HIV-1 Molecular Networks Reveal Effective Control of Large Transmission Clusters in an Area Affected by an Epidemic of Multiple HIV Subtypes.TIF by Mingchen Liu (9637724)

“…The dynamics of large clusters were estimated by proportional detection rate (PDR), cluster growth predictor, and effective reproductive number (R_e). Most large clusters showed decreased or stable during the study period, indicating that expansion was slowing. …”

Growth and behavioral defects in <i>lov⁴⁷</i> larvae. by Sonia M. Bjorum (404513)

Data_Sheet_1_Physiological and transcriptome analyses reveal the photosynthetic response to drought stress in drought-sensitive (Fengjiao) and drought-tolerant (Hanjiao) Zanthoxylu... by Haichao Hu (1510828)

“…“Hanjiao”) was analyzed under drought stress using physiological indicators and transcriptome data. Drought decreased stomatal aperture and stomatal conductance (Gsw), reduced transpiration rate (E) and sub-stomatal CO₂ concentration (Ci), and lowered chlorophyll and carotenoid content, which reduced the net photosynthetic rate (Pn) of Z. bungeanum. …”

IFT mutant fish develop and maintain a functional BRB. by Lana M. Pollock (9193262)

“…Some autofluorescence (likely from the lens) is observed in the areas outside of the hyaloid vessels (arrowhead in D). (E) As an example of BRB breakdown, <i>Tg(l-fabp</i>:<i>DBP-EGFP;flk1</i>:<i>mCherry)</i> embryos were treated with 0.15 μM BMS493, an inhibitor of retinoic acid signaling, from 2 dpf until 7 dpf. …”

Low-Field Dynamic Magnetic Separation by Self-Fabricated Magnetic Meshes for Efficient Heavy Metal Removal by Xiangxia Wei (4503091)

“…In the end, after one filtration process, the heavy metal concentration can be significantly decreased from 1.0 mg L^–1 to below the drinking water standard recommended by the World Health Organization (e.g., less than 0.01 mg L^–1 for Pb). …”

Microbial Communities in Full-Scale Wastewater Treatment Systems Exhibit Deterministic Assembly Processes and Functional Dependency over Time by Jinjin Yu (788889)

“…In contrast, the occurrence of sludge bulking and foaming in the activated sludge system led to an increase in stochastic assembly processes (i.e., limited dispersal and undominated events), a shift toward functional redundancy and less community diversity, a decreased community niche breadth index, and a more compact co-association network. …”

Image_3_Serglycin-Deficiency Causes Reduced Weight Gain and Changed Intestinal Cytokine Responses in Mice Infected With Giardia intestinalis.tif by Zhiqiang Li (102723)

“…<p>The proteoglycan serglycin (SG) is expressed by different innate and adaptive immune cells, e.g. mast cells, macrophages, neutrophils, and cytotoxic T lymphocytes, where SG contributes to correct granule storage and extracellular activity of inflammatory mediators. …”

Metasurface Measuring Twisted Light in Turbulence by Thomas Dinter (6976187)

Table_1_Axitinib Reverses Resistance to Anti-Programmed Cell Death-1 Therapy in a Patient With Renal Cell Carcinoma.xls by Yonghao Yang (3415943)

“…Herein, we report the case of a 58-year-old woman with renal cell carcinoma associated with Xp11.2 translocation/transcription factor E3 gene fusion, who had already showed resistance to both anti-PD-1 monotherapy and standard-dose axitinib. …”

Image1_Synaptic and functional alterations in the development of mutant huntingtin expressing hiPSC‐derived neurons.TIF by Margarita C. Dinamarca (13115538)

Tracking Endogenous Amelogenin and Ameloblastin <i>In Vivo</i> by Jaime Jacques (578442)

“…Moreover, in mandibular tissues AMELX and AMBN mRNA levels varied according to two parameters: 1) ontogenic stage (decreasing with age), and 2) tissue-type (<i>e.g.…”

Tamoxifen Ameliorates Peritoneal Membrane Damage by Blocking Mesothelial to Mesenchymal Transition in Peritoneal Dialysis by Jesús Loureiro (405934)

“…Tamoxifen blocked the MMT induced by transforming growth factor (TGF)-β1, as it preserved the expression of E-cadherin and reduced the expression of mesenchymal-associated molecules such as snail, fibronectin, collagen-I, α-smooth muscle actin, and matrix metalloproteinse-2. …”