Alterations in the relative abundance of <i>Faecalibacterium prausnitzii</i> correlate with changes in fecal calprotectin in patients with ileal Crohn’s disease: a longitudinal stu... by Olle Björkqvist (6712793)

Caveolin-1 Plays a Crucial Role in Inhibiting Neuronal Differentiation of Neural Stem/Progenitor Cells via VEGF Signaling-Dependent Pathway by Yue Li (102191)

“…Moreover, the enhanced phosphorylations of p44/42MAPK, Akt and Stat3, and neuronal differentiation were abolished by co-treatment of VEGF inhibitor V1. These results provide strong evidence to prove that Cav-1 can inhibit neuronal differentiation via down-regulations of VEGF, p44/42MAPK, Akt and Stat3 signaling pathways, and that VEGF signaling is a crucial target of Cav-1. …”

An integrated digital healthcare platform for diabetes management with AI-based dietary management: 48-week results from a randomized controlled trial by You-Bin Lee (3391988)

DataSheet_1_Fractionation of toxic metal Pb from truly dissolved and colloidal phases of seaward rivers in a coastal delta.docx by Peng Ren (337555)

DataSheet4_A comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta.docx by Yan Feng (128912)

“…</p><p>Conclusion: Our findings provide a profile of the dysregulated steroid hormone biosynthesis in PE placenta, we observed a dysregulated cortisol-to-cortisone ratio, testosterone accumulation, decreased testosterone downstream metabolites, impaired production of estrone and estriol, and aberrant hydroxylation and methylation of estradiol. …”

Experiences in responders and non-responders to pulmonary rehabilitation among people with chronic obstructive pulmonary disease: a clinical study with convergent mixed analysis by Charlotte Simonÿ (10574466)

Table 1_Antidiabetic agent use and clinical outcomes in patients with diabetes hospitalized for COVID-19: a systematic review and meta-analysis.xlsx by Jordan N. Keels (20356608)

“…</p>Purpose<p>To examine the relationship between antidiabetic agent use and clinical outcomes in individuals with DM hospitalized for COVID-19.</p>Methods<p>A systematic review of the literature (2020-2024) was performed across five databases. …”

Association of maternal methionine synthase reductase gene polymorphisms with the risk of congenital heart disease in offspring: a hospital-based case-control study by Jianhui Wei (10970457)

Data_Sheet_1_Macrophages Down-Regulate Gene Expression of Intervertebral Disc Degenerative Markers Under a Pro-inflammatory Microenvironment.docx by Ana J. Silva (6906773)

Table_1_Calorie-restricted diet mitigates weight gain and metabolic abnormalities in obese women with schizophrenia: a randomized controlled trial.DOC by Lei Zhang (38117)

“…Compared to the normal diet, adherence to the CRD significantly decreased body weight (2.38 ± 1.30 kg), body mass index (0.94 ± 0.52 kg/m²), waist circumference (4.34 ± 2.75 cm), hip circumference (3.37 ± 2.36 cm), mid-upper circumferences, triceps skin-fold thickness, fat mass and free fat mass with large effect sizes (p = <0.001, ηp² range between 0.145 and 0.571), as well as total cholesterol (0.69 ± 0.70 mmol/L) with a medium effect size (p = 0.028, ηp² = 0.054). …”

DataSheet3_A comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta.xlsx by Yan Feng (128912)

“…</p><p>Conclusion: Our findings provide a profile of the dysregulated steroid hormone biosynthesis in PE placenta, we observed a dysregulated cortisol-to-cortisone ratio, testosterone accumulation, decreased testosterone downstream metabolites, impaired production of estrone and estriol, and aberrant hydroxylation and methylation of estradiol. …”

DataSheet1_A comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta.xlsx by Yan Feng (128912)

“…</p><p>Conclusion: Our findings provide a profile of the dysregulated steroid hormone biosynthesis in PE placenta, we observed a dysregulated cortisol-to-cortisone ratio, testosterone accumulation, decreased testosterone downstream metabolites, impaired production of estrone and estriol, and aberrant hydroxylation and methylation of estradiol. …”

DataSheet2_A comprehensive analysis of metabolomics and transcriptomics to reveal major metabolic pathways and potential biomarkers of human preeclampsia placenta.xlsx by Yan Feng (128912)

“…</p><p>Conclusion: Our findings provide a profile of the dysregulated steroid hormone biosynthesis in PE placenta, we observed a dysregulated cortisol-to-cortisone ratio, testosterone accumulation, decreased testosterone downstream metabolites, impaired production of estrone and estriol, and aberrant hydroxylation and methylation of estradiol. …”

Spontaneous glutamate transients and neuronal activity after blockade of specific pathways of glutamate transport and release. by Saju Balakrishnan (58265)

“…<b><i>E</i></b><i>–</i>Application of ACSF containing 5% dextran decreased the amplitude and frequency of glutamate spikes. …”

Supplementary Figure 3 from miR-34a Silences c-SRC to Attenuate Tumor Growth in Triple-Negative Breast Cancer by Brian D. Adams (1701025)

Figure 7 from N-Myristoytransferase Inhibition Causes Mitochondrial Iron Overload and Parthanatos in TIM17A-Dependent Aggressive Lung Carcinoma by Sofia Geroyska (19217412)

Screening for Novel LRRK2 Inhibitors Using a High-Throughput TR-FRET Cellular Assay for LRRK2 Ser935 Phosphorylation by Spencer B. Hermanson (139911)

“…Phosphorylation at Ser935 in these cells is detected using a terbium labeled anti-phospho-Ser935 antibody that generates a TR-FRET signal between terbium and GFP. …”

Data_Sheet_1_Ataxia with oculomotor apraxia type 2 caused by a novel homozygous mutation in SETX gene, and literature review.docx by Shuaishuai Chen (7275431)

“…She had elevated AFP, increased serum follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and decreased anti-Müllerian hormone (AMH) levels. We identified a novel homozygous missense mutation of the SETX gene, c.7118 C>T (p. …”

PrP^CGPIThy-1 L150 mice show a delay to terminal disease and altered neuropathology upon prion infection. by Berta Puig (344828)

“…Chart underneath shows mean relative intensity of PrP referred to actin where WTPrP^C samples are set to 100% as a reference (error bars are SEM; n = 5 for each genotype). …”

Data Sheet 1_A randomized, sham-controlled clinical trial to evaluate the NET Device™ for reducing withdrawal symptom severity during opioid discontinuation.pdf by Mark K. Greenwald (6897305)

“…COWS scores decreased more for active (-11.1 ± 5.2) than sham (-8.8 ± 6.3), p<.05, d=-.41. …”