Table_1_Correlative analysis from a phase I clinical trial of intrapleural administration of oncolytic vaccinia virus (Olvi-vec) in patients with malignant pleural mesothelioma.doc... by Navin K. Chintala (14631764)

“…Vaccinia virus was detectable in tumor cells 2-5 days post-treatment, and treatment was associated with a decrease in tumor cell density and an increase in immune cell density as assessed by a pathologist blinded to the clinical observations. …”

Long function evolution of the montelukast and placebo group. by David Ruttens (5071316)

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…RNLEs includes 12 common negative life events that have occurred in the past year, and were classified as low RNLEs (0 RNLEs), intermediate RNLEs (1–5 RNLEs), and high RNLEs (6–12 RNLEs). A healthy lifestyle score in adulthood was constructed as the sum of five modifiable lifestyle factors (i.e., smoking status, drinking status, regular physical activity, sleep duration, and living alone), and was classified as unfavorable [0–2 points], intermediate [3 points], and favorable [4–5 points] groups. …”

Supplementary Material for: Underwater Clip Closure versus Conventional Clip Closure following Endoscopic Submucosal Dissection in Colorectal Lesions: A First Comparative Study by figshare admin karger (2628495)

“…Multiple regression analysis identified both resection area (p < 0.001) and closure method (p = 0.002) as independent factors affecting closure time. Conclusion UCC may decrease the time required for post-ESD closure of colorectal lesions measuring ≤5 cm, while using a comparable number of clips to CCC, with no serious complications.…”

Morphology, interfacial interaction, and thermal degradation of polycarbonate/MCM-41 (nano)composites by Sibeko, M.A.

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DataSheet1_Trabecular bone remodeling in the aging mouse: A micro-multiphysics agent-based in silico model using single-cell mechanomics.docx by Daniele Boaretti (13030515)

“…Notably, in silico models are regarded as powerful tools to further understand the signaling pathways that regulate this intricate spatial cellular interplay. To this end, we have established a 3D multiscale micro-multiphysics agent-based (micro-MPA) in silico model of trabecular bone remodeling using longitudinal in vivo data from the sixth caudal vertebra (CV6) of PolgA^{(D257A/D257A)} mice, a mouse model of premature aging. …”

Inhibitory effect of TF3 on Hla production by <i>Staphylococcus aureus</i> USA300. by Anna Goc (316065)

“…(B) Densitometry of western blot bands. (C) Dose-dependent decrease in <i>hla</i> and <i>agr</i>A genes expression by <i>S</i>. …”

Building the foundation for a community-generated national research blueprint for inherited bleeding disorders: research priorities for ultra-rare inherited bleeding disorders by Diane Nugent (14796787)

“…Without disorder-appropriate treatment, affected individuals potentially face life-threatening bleeding, delayed diagnosis, suboptimal management of invasive procedures, psychosocial distress, pain, and decreased quality-of-life.</p> <p>The National Hemophilia Foundation (NHF) and the American Thrombosis and Hemostasis Network identified the priorities of people with inherited BDs and their caregivers, through extensive inclusive community consultations, to inform a blueprint for future decades of research. …”

Data_Sheet_1_Assessing causal relationships between sarcopenia and nonalcoholic fatty liver disease: A bidirectional Mendelian randomization study.DOCX by Ze-Hua Zhao (3451817)

“…However, whether there are causal relationships between sarcopenia and NAFLD remains undetermined. Here, we aim to address the question using a two-sample bidirectional Mendelian randomization (MR) analysis approach.…”

Caveolin-1 Plays a Crucial Role in Inhibiting Neuronal Differentiation of Neural Stem/Progenitor Cells via VEGF Signaling-Dependent Pathway by Yue Li (102191)

“…<div><p>In the present study, we aim to elucidate the roles of caveolin-1(Cav-1), a 22 kDa protein in plasma membrane invaginations, in modulating neuronal differentiation of neural progenitor cells (NPCs). …”

Video_1_Vagus nerve stimulation allows to cease maintenance electroconvulsive therapy in treatment-resistant depression: a retrospective monocentric case series.MP4 by Oumaima Aboubakr (17279054)

“…At last follow-up, 4 (57%) patients had stopped ECT. Five (71%) patients implanted with VNS were good responders (50% decrease relative to baseline MADRS). …”

Data Sheet 1_Microbial communities and their association with soil health indicators under row cash crop and cover crop diversification: a case study.pdf by Rachel Wooliver (670638)

“…-soybean] annual crop rotation with a five-species winter cover crop mix. We characterized bacterial and fungal communities at three timepoints per year (spring, fall, summer) and quantified a suite of soil health indicators at each timepoint.…”

Supplementary Material for: Participant characteristics associated with changes in mental health in a trial of behavioural weight management programmes: Secondary analysis of the W... by Jones R.A. (12411430)

“…It is important to identify those at risk of harm to provide more effective psychological support. We aimed to identify participant characteristics associated with changes in depression and anxiety in participants of a behavioural weight management programme. …”

Effect Of Aspect Ratio On Torsional Capacity Of High-Strength Plain Concrete Deep Beams by Samman, Tamim A.

“…Concrete strengths of 51.01, 58.53, 76.60 and 83.66 MPa and depth/width (aspect) ratios varying from 1 to 5 were used. The tested beams failed suddenly and violently along a smooth surface. …”
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Table2_Identify Tcea3 as a novel anti-cardiomyocyte hypertrophy gene involved in fatty acid oxidation and oxidative stress.xls by Yingying Guo (318604)

“…Subsequently, RT-PCR results showed that knockdown of Tcea3 up-regulated Ces1d and Pla2g5 mRNA expression levels. In PE induced cardiomyocyte hypertrophy, Tcea3 silencing results in decreased fatty acid utilization, decreased ATP synthesis and increased mitochondrial oxidative stress.…”

Table1_Identify Tcea3 as a novel anti-cardiomyocyte hypertrophy gene involved in fatty acid oxidation and oxidative stress.docx by Yingying Guo (318604)

“…Subsequently, RT-PCR results showed that knockdown of Tcea3 up-regulated Ces1d and Pla2g5 mRNA expression levels. In PE induced cardiomyocyte hypertrophy, Tcea3 silencing results in decreased fatty acid utilization, decreased ATP synthesis and increased mitochondrial oxidative stress.…”

Inhibitory effect of theaflavins and catechins on Hla secretion by <i>Staphylococcus aureus</i>. by Anna Goc (316065)

“…<p>(A) Dose-dependent decrease in Hla secretion by <i>S</i>. …”

Data_Sheet_1_Greensporone C, a Freshwater Fungal Secondary Metabolite Induces Mitochondrial-Mediated Apoptotic Cell Death in Leukemic Cell Lines.pdf by Kirti S. Prabhu (4246144)

“…Antitumor activity of greensporone C (GC), a new resorcylic acid lactone isolated from an organic extract of a culture of a Halenospora sp. freshwater fungus, was subjected for screening against a panel of leukemic cell lines (K562, U937, and AR320). …”

Regional Variation in Acute Kidney Injury Requiring Dialysis in the English National Health Service from 2000 to 2015 – A National Epidemiological Study by Nitin V. Kolhe (300674)

“…We therefore studied regional variation in the epidemiology of AKI-D in English National Health Service over a period of 15 years.…”

DataSheet_1_Anti-diabetic combination therapy with pioglitazone or glimepiride added to metformin on the AGE-RAGE axis: a randomized prospective study.pdf by Eugenio Ragazzi (2211859)

“…The aim of this study was to evaluate in the diabetes condition the influence of two different oral anti-diabetic treatments on the AGE/s-RAGE ratio, during a 5-year observation period.</p>Methods<p>Seventy-three patients with type 2 diabetes mellitus were randomly assigned to a drug therapy with pioglitazone or glimepiride, combined to metformin. …”