Aged mated and unmated germlines maintain DSB-2 localization in early pachytene. by Erik Toraason (5724689)

Subjects:

Data_Sheet_2_High Rates of Genome Rearrangements and Pathogenicity of Shigella spp..CSV by Zaira Seferbekova (10583336)

“…The high rearrangement rate resulted in independent disruption of syntenic regions and parallel rearrangements in different Shigella lineages. Specifically, we identified two types of chromosomally encoded E3 ubiquitin-protein ligases acquired independently by all Shigella strains that also showed a high level of sequence conservation in the promoter and further in the 5′-intergenic region. …”

LincRNA-miRNA-mRNA regulatory network during skeletal muscle development. by Yalan Yang (735975)

Growth curves expressed in cell.mL^-1 of <i>E</i>. <i>paludosa</i> (A), <i>N</i>. <i>alexandrina</i> (B), and <i>Staurosira</i> sp. (C) as a function of time under differ... by Eva Cointet (7828550)

The affected dogs have a complete loss of IP₃R3 and reduced IP₃R1 and IP₃R2 protein levels. by Marjo K. Hytönen (8522271)

Macrocyclic Metalloenediynes of Cu(II) and Zn(II):  A Thermal Reactivity Comparison by Tilak Chandra (1586797)

“…Specifically, as the size of the macrocycle increases, the temperatures at which these compounds undergo Bergman cyclization decrease by ∼5 °C per additional carbon atom, leading to an overall decrease across the series of 19 °C. …”

Old rats present impaired wound healing compared to young rats. by María Paz Saldías (4430032)

Differentially expressed <i>E</i>. <i>coli</i> cellular proteins in response to treatment with titanium dioxide nanoparticles. by Mariane Planchon (279941)

As a result of the clean vehicle rebate project, net local SO₂ and NO_X emissions decrease more for least disadvantaged communities than for disadvantaged comm... by Jaye Mejía-Duwan (15401425)

PPA between Fusion^® SARS-CoV-2 pooled test results and neat test results from three SARS-CoV-2 assays. by Rudolph Park (14070418)

Table_1_Empagliflozin Decreases Lactate Generation in an NHE-1 Dependent Fashion and Increases α-Ketoglutarate Synthesis From Palmitate in Type II Diabetic Mouse Hearts.DOCX by Hong Zhang (25820)

“…</p><p>Conclusions: The present study shows for the first time that the SGLT2 inhibitor Empagliflozin has acute specific metabolic effects in isolated diabetic hearts, i.e., decreased lactate generation from labeled glucose and increased α-ketoglutarate synthesis from labeled palmitate. …”

Identification and Characterization of a Leoligin-Inspired Synthetic Lignan as a TGR5 Agonist by Alexander F. Perhal (20946742)

“…We showed that LT-188A (<b>1</b>) decreased the levels of production of these inflammatory mediators in macrophages. …”

Viral ORF57 inhibits eIF2α phosphorylation through down-regulation of PKR pathway. by Nishi R. Sharma (4543936)

“…<p>(A) Diagrams of four major stress pathways leading to phosphorylation of eIF2α via different kinases. PERK, PKR-like endoplasmic reticulum kinase; PKR, protein kinase R; GCN2, general control nonderepressible 2; HRI, heme regulated inhibitory kinase. …”

Table_5_Exploring the multifaceted therapeutic mechanism of Schisanlactone E (XTS) in APP/PS1 mouse model of Alzheimer’s disease through multi-omics analysis.XLSX by Zhenyan Song (17434881)

“…After an acclimatization period of 7 days, intraperitoneal injections were administered over a 60-day treatment period. The NC and M groups received saline, while the Tre group received XTS at 2 mg/kg. …”

The role of the ER stress sensor PERK in ox-LDL-induced NO decrease in HCMECs. by Dan Hong (731836)

Junction assembly in 3D cell cultures is severely impaired for W2A mutant. by Stefanie Bunse (491659)

“…At 3 h (inset) the roundness of all mutants was significantly lower than WT. W2A and V81D/V174D had significantly lower roundness even after 20 h and 48 h of spheroid formation (two-tailed unpaired, t-test, P < 0.05). n(WT) = 9, n(W2A) = 9, n(R14E) = 8, n(V81D/V174D) = 8 spheroids. …”

Gene expression analysis of T3-regulated genes <i>Dio1</i>, <i>Gsta2</i> and <i>Ucp2</i> in the liver and <i>Hcn2</i>, <i>Atp2a2</i>, <i>Myh6 and Myh7</i> in heart of vehicle treat... by Soledad Bárez-López (607514)

Fabrication of (a) schematic diagram of solid oxide fuel cell using GDC/BNMO/LSCO and (b) shows the cell components that serve as structural materials. by Nacer Badi (14046883)

Supplementary Material for: A Novel Mask with Selective Ports for Inflow and Outflow Reduces CO₂ Rebreathing during Non-Invasive Ventilation: A Physiological Study in He... by Rezoagli E. (14097681)

“…In phase 1, six ventilation settings were tested for each mask: CPAP (PEEP 5 cmH₂O) and pressure support ventilation (PSV, PS Level 5 cmH₂O) using a mechanical ventilator with a bias flow of 8 or 20 L/min; free-flow CPAP (PEEP 5 cmH₂O) with 60 or 90 L/min of gas flow. …”

DataSheet1_CYP3A5 influences oral tacrolimus pharmacokinetics and timing of acute kidney injury following allogeneic hematopoietic stem cell transplantation.docx by Nathan D. Seligson (10358404)

“…Additionally, Expression of CYP3A5 *1 was associated with decreased risk of developing AKI as an inpatient (p = 0.06). …”