CaMKII inhibition attenuates apoptosis in rat hippocampal slice cultures exposed to oxygen glucose deprivation. by Qing Lu (28914)

“…<p>Rat hippocampal slice cultures were exposed to OGD in the presence of the CaMKII inhibitor, KN93 or its inactive analog, KN92 (10 µM, 2 h prior to OGD). Slices were harvested 8 h after OGD and subjected to Western blot analysis to determine effects on cleaved caspase-3 (A). …”

Image_1_Effects of Circular RNA of Chicken Growth Hormone Receptor Gene on Cell Proliferation.TIF by Haidong Xu (35210)

“…Real-time PCR showed that circGHR was increased from E13 to the 7th week in the liver but decreased in the thigh and breast muscle. …”

LNA-anti-miR-182 and -381 had anticancer effects on glioma cells and subcutaneously transplanted tumors in nude mice. by Hailin Tang (129690)

“…(B) LNA-mediated miR-182 and -381 silencing blocked cell cycle progression in the G0/G1 phase, induced pRb expression, and decreased E2F3 expression. (C) <i>BRD7</i> silencing inhibited the proliferation of glioma cells and blocked the cell cycle in the G0/G1 phase. * <i>p</i><0.05 compared with control (siRNA scrambled). …”

siRNA knockdown of miR-574-3p target genes and effect on PCa cell viability. by Takeshi Chiyomaru (140914)

“…Representative images of wound healing assay are shown at 200× magnification. (E) Knockdown of RAC1, EGFR and EP300 significantly decreased cell invasion. …”

Effects of U0126, T0070907, and Pioglitazone hydrochloride (Pio) on NO production in LPS-stimulated RAW264.7 macrophages. by Xiang Li (114679)

“…ENL does-dependently attenuated NO secretion, U0126, T0070907, and Pio further strengthened ENL's effect. 50 µM SDL also showed NO inhibition activity, while U0126 enhanced SDL's effect. * Means compared with model group (200 ng/ml LPS treated alone), and # stands for statistic significance analysis between two groups with and without small molecular tool drugs (<i>i.e.…”

Overview Experiment 1. by Ivar R. Kolvoort (18349698)

“…Each sample was numbered (e.g. ‘Weather #23’) to emphasize that they represented individual instantiations of the causal variables. …”

The role of HIF-α pathyway in osteocyte morphology. by Gui-lai Zuo (711620)

“…The number of dendrites is significantly decreased and less interconnected in the ΔVHL mice. …”

Image_4_Diet drives the gut microbiome composition and assembly processes in winter migratory birds in the Poyang Lake wetland, China.TIF by Binhua Wang (8769938)

“…Microbial networks for the gut microbiome of the herbivorous and carnivorous were less integrated, i.e., had lower average node degree and greater decreased network stability upon node attack removal than those of the omnivorous birds. …”

Integrating Flux Balance Analysis into Kinetic Models to Decipher the Dynamic Metabolism of <em>Shewanella oneidensis</em> MR-1 by Xueyang Feng (185519)

“…The dFBA profiled biologically meaningful dynamic MR-1 metabolisms: 1. the oxidative TCA cycle fluxes increased initially and then decreased in the late growth stage; 2. fluxes in the pentose phosphate pathway and gluconeogenesis were stable in the exponential growth period; and 3. the glyoxylate shunt was up-regulated when acetate became the main carbon source for MR-1 growth.…”

Quantification of Ki67 Staining in Rat Pulmonary Arteries. by Daniel J. Kass (173086)

“…Magnification ×400, inset line 20 mm. (E) Ki67+ nuclei in the medial layer (n = 4–6 per group) and (F) Ki67+ nuclei in endothelial cells of the pulmonary arteries (n = 4 per group) were quantified per hpf as described in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0035388#s2" target="_blank">Materials and Methods</a>. …”

Multiple endophenotypes exhibited by <i>bbs</i> mutants. by Calvin A. Mok (201207)

“…Kruskal-Wallis with Dunn's, *** p<0.001, n≥25, N≥2 replicates. Data represent mean squares roamed ± SEM. …”

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception by Shameem Sultana Syeda (1277550)

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception by Shameem Sultana Syeda (1277550)

CHD8 knockdown in B-ALL cells leads to cell death without a cell cycle arrest. by Jennifer R. Shingleton (829013)

“…<b>(C)</b> Bar graph showing increased <i>CCNE1</i> and <i>CCNE2</i> expression upon CHD8 knockdown. Shown are averages ± SD. …”

Data_Sheet_1_The postbiotic of hawthorn-probiotic ameliorating constipation caused by loperamide in elderly mice by regulating intestinal microecology.zip by Yu Wei (365236)

“…</p>Results<p>Postbiotic of hawthorn-probiotic improved intestinal movement and pathomorphology, elevated AQP3, Enac-γ and mucin-2 expression, accompanied by decreased serum TNF-α and cell apoptosis, but increased proliferation. …”

Design, Synthesis, and in Vitro and in Vivo Evaluation of Ouabain Analogues as Potent and Selective Na,K-ATPase α4 Isoform Inhibitors for Male Contraception by Shameem Sultana Syeda (1277550)

Data_Sheet_1_The msaABCR Operon Regulates Persister Formation by Modulating Energy Metabolism in Staphylococcus aureus.docx by Shanti Pandey (4612024)

“…We also showed that msaABCR (through MsaB) represses the ccpE and ndh₂ genes, thereby regulating TCA cycle activity and the generation of membrane potential, respectively. …”

Image_1_Diet drives the gut microbiome composition and assembly processes in winter migratory birds in the Poyang Lake wetland, China.TIF by Binhua Wang (8769938)

“…Microbial networks for the gut microbiome of the herbivorous and carnivorous were less integrated, i.e., had lower average node degree and greater decreased network stability upon node attack removal than those of the omnivorous birds. …”

Recovery of Rare Earth Elements from Low-Grade Feedstock Leachates Using Engineered Bacteria by Dan M. Park (473553)

“…Herein, we engineered <i>E. coli</i> cells for enhanced cell surface-mediated extraction of REEs by functionalizing the OmpA protein with 16 copies of a lanthanide binding tag (LBT). …”

Image_4_Effects of Circular RNA of Chicken Growth Hormone Receptor Gene on Cell Proliferation.TIF by Haidong Xu (35210)

“…Real-time PCR showed that circGHR was increased from E13 to the 7th week in the liver but decreased in the thigh and breast muscle. …”