OCA alone markedly decreases and combined with Gemcitabine or Cisplatin abrogates growth of iCCA xenografts. by S. Di Matteo (6260417)

“…After 4 weeks, when the tumor size was approximately 100 mm³ (T₀) mice were treated with OCA (0.03% w/w, 30 mg/kg) alone or combined with Cisplatin (2.4 mg/Kg in 100 μl) or Gemcitabine (1.05 mg/Kg in 100 μl) for 5 additional weeks. a) Results are expressed as percent increase in tumor volume at different time points. …”

Pathways of macrophages and neutrophils were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Sample-enrichment analysis (SLEA) of pathways of monocytes, macrophages M1 and M2 pathways, and neutrophils signaling at 4 dpi following SARS-CoV-2 challenge in vaccinated hamsters (shown in pink and blue colors), sham unvaccinated hamsters (shown in green) and in naïve control hamsters (shown in red). …”

SOCS3 decreases IL-10 secretion and increases IL-6 release in fetal type II cells exposed to mechanical stretch. by Michael A. Hokenson (391291)

Compressive strength as a function of glass fiber layers modified GFRPs. by Shaban Gul (14309526)

Subjects:

Proinflammatory signaling pathways were decreased in Ad26.COV2.S vaccinated compared to sham unvaccinated hamsters. by Malika Aid (7303874)

“…<p><b>(A)</b> Boxplots of SARS-CoV-2 transcripts normalized read counts across all animals, vaccinated hamsters are shown in blue and pink, and sham animals in green. …”

Blocking specific receptor-ligand interactions can decrease deformation, invasion and echinocytosis of the host erythrocyte. by Greta E. Weiss (248607)

Odds ratios (OR) and 95% confidence intervals (CI) calculated with conditional logistic regression for the association of pancreatic cancer with decrease in body mass index (BMI) i... by Agnieszka Lemanska (13911532)

Numerical data values for Figs 2B, 3C, 3D, 4B, 4C, 5A, 5B, 5C, 5D, 6D, 6F, 8A, 8B, 8C, 8D, 9D and 9E. by Shweta Singh (409313)

CD43^-/- septic mice exhibit decreased frequencies of apoptotic CD8⁺ T_EM as compared to WT septic mice. by Katherine T. Fay (2576998)

“…D) There was a significant decrease in apoptosis of CD44^HI CD62L^LO CD8⁺ T_EM in CD43^-/- septic mice compared to WT septic mice (10.3±1.1 vs 17.9±1.9, p = 0.006). …”

LdAg-based prophylactic vaccine decreases <i>Leishmania</i> parasitic burden. by Doumet Georges Helou (7255823)

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_1_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_3_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Image_2_Loss of early B cell protein λ5 decreases bone mass and accelerates skeletal aging.jpeg by Mohamed Khass (695111)

“…The trabecular bone volume over total volume (BV/TV) in J_H^-/- mice was similar to WT mice at all ages. In contrast, at six months of age and thereafter, λ5^-/- and J_H^-/-λ5^-/- mice demonstrated a severe decrease in trabecular bone mass. …”

Loss of PI3K activity reduces Notch signaling by decreasing N1ICD stability. by Hongge Li (437334)

Over-expression of YKL-40 in 76N MECs decreases E-cad and β-casein, but increases MMP-9 expression and cell invasiveness. by Steve Scully (202724)

Nucleophilicity of Oximes Based upon Addition to a Nitrilium <i>closo</i>-Decaborate Cluster by Dmitrii S. Bolotin (1953220)

“…Three types of oxime species, i.e., 4-morpholyl­carb­ami­doxime (hydroxy­guanidine), phenyl­acet­amidoxime and benzamidoxime (amidoximes), and cyclo­hexanone oxime and benzo­phenone oxime (ketoximes), react at room temperature with the 2-nitrilium <i>closo</i>-decaborate clusters, leading to 2-iminium <i>closo</i>-decaborates (14 examples; 57–94%). …”

Nucleophilicity of Oximes Based upon Addition to a Nitrilium <i>closo</i>-Decaborate Cluster by Dmitrii S. Bolotin (1953220)

“…Three types of oxime species, i.e., 4-morpholyl­carb­ami­doxime (hydroxy­guanidine), phenyl­acet­amidoxime and benzamidoxime (amidoximes), and cyclo­hexanone oxime and benzo­phenone oxime (ketoximes), react at room temperature with the 2-nitrilium <i>closo</i>-decaborate clusters, leading to 2-iminium <i>closo</i>-decaborates (14 examples; 57–94%). …”