Acss2/HIF-2 regulates cancer-associated factors in HT29 cells. by Joseph A. Garcia (7865855)

Acss2/HIF-2 regulates cancer-associated factors in HCT116 cells. by Joseph A. Garcia (7865855)

HOXA2 control of target enhancers. by Laure Bridoux (481118)

“…Strong HOX and TALE binding is observed in both tissues, with higher acetylation levels in BA2. B. Heatmap shows <i>Meis2 and Zfp703</i> expression in E11.5 mouse BA1, BA2 and PBA, based on the normalized expression values CPM [<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1009162#pgen.1009162.ref030" target="_blank">30</a>]. …”

Data_Sheet_2_Differences in the Seed Germination of Leymus chinensis (Poaceae) Ecotypes Reveal Distinct Strategies for Coping With Salinity Stress: A Common Garden Experiment.CSV by Meng-Yao Ma (11434510)

“…As the salinity level increased, the radicle length of the two ecotypes decreased; however, GG had longer radicles and a higher number of radicles, even at 200 mM NaCl when no radicle protruding from the seed coat was detected in YG. …”

Magnetic resonance anatomical imaging and selective fat imaging in control (Ctr) and <i>lepb</i>-deficient (<i>lepb</i>^<i>-/-</i>) adult zebrafish. by Muhamed N. Hashem Eeza (15295543)

A missense variant in <i>FTCD</i> is associated with arsenic metabolism and toxicity phenotypes in Bangladesh by Brandon L. Pierce (181635)

“…Among the 19,992 coding variants analyzed exome-wide, the minor allele (A) of rs61735836 (p.Val101Met) in exon 3 of <i>FTCD</i> (formiminotransferase cyclodeaminase) was associated with increased urinary iAs% (P = 8x10^-13), increased MMA% (P = 2x10^-16) and decreased DMA% (P = 6x10^-23). …”

Mendelian randomization results with COVID-19. by Alish B. Palmos (5857379)

Stimulation of iNKT Cells with α-GalCer during an Established <i>L. donovani</i> Infection Results in a Decreased Frequency of Hepatic iNKT Cells Producing IFNγ and TNF, and an Inc... by Amanda C. Stanley (42433)

RPMI-8226/hRANKL/eGFP-bearing mice have elevated serum soluble RANKL, increased osteoclast number and reduced trabecular bone volume. by Clive Henry Buckle (309400)

“…E. RPMI-8226/hRANKL/eGFP-treated mice have decreased trabecular bone volume (27%) when compared to RPMI-8226/eGFP cell-bearing animals. …”

Developmental competence and mtDNA residue in mouse SCCT-generated embryos in vivo. by Xiaoyu Liao (8161995)

MtDNA replacement in human oocytes with MRR-SCCT procedure. by Xiaoyu Liao (8161995)

S1 Data - by Angélica González Maciel (18946369)

“…Estimation of Purkinje neurons in mid-sagittal slices of the cerebellum of control and Giardia intestinalis parasitized gerbils by Cresyl violet staining (Normal) and the TUNEL technique (mean and SD). Tab E. Data for <a href="http://www.plosntds.org/article/info:doi/10.1371/journal.pntd.0012302#pntd.0012302.t002" target="_blank">Table 2</a>. …”

Summary of the 44 features used for prediction. by Daniel A. Adler (12468970)

Table 3_E-ACTIVE AGING study protocol: Evaluating an exergame-based and multicomponent exercise program for community-dwelling older adults at risk of falling.docx by Paloma Lillo-Urzúa (22767998)

Table 1_E-ACTIVE AGING study protocol: Evaluating an exergame-based and multicomponent exercise program for community-dwelling older adults at risk of falling.docx by Paloma Lillo-Urzúa (22767998)

Data_Sheet_1_Rbfox1 Is Expressed in the Mouse Brain in the Form of Multiple Transcript Variants and Contains Functional E Boxes in Its Alternative Promoters.docx by Sonia Casanovas (8799128)

“…Using reporter assays we found that the promoter regions of the two first exons E1B and E1C/E1C.1 contain several functional E-boxes. …”

Expression of CRYAB in normal and tumor tissue samples across different cancer types. by Rasool Saghaleyni (10526301)

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”

Design and Synthesis of Novel Epigenetic Inhibitors Targeting Histone Deacetylases, DNA Methyltransferase 1, and Lysine Methyltransferase G9a with <i>In Vivo</i> Efficacy in Multip... by Obdulia Rabal (124515)

“…The corresponding epigenetic functional cellular responses are observed: histone-3 acetylation, DNA hypomethylation, and decreased histone-3 methylation at lysine-9. These chemical probes, multitarget epigenetic inhibitors, were validated against the multiple myeloma cell line MM1.S, demonstrating promising <i>in vitro</i> activity of <b>12a</b> (CM-444) with GI₅₀ of 32 nM, an adequate therapeutic window (>1 log unit), and a suitable pharmacokinetic profile. …”