Monoacidic Inhibitors of the Kelch-like ECH-Associated Protein 1: Nuclear Factor Erythroid 2‑Related Factor 2 (KEAP1:NRF2) Protein–Protein Interaction with High Cell Potency Identi... by Thomas G. Davies (2606863)

NRF2 positively modulates CSCC cellular malignant phenotypes. by Jun-Qi Ma (135472)

“…<p>A, D, G and J: Cell apoptosis, Proliferation, Migration and invasion in Siha cells, respectively (Normal controls). B, E, H and K: a Knockdown of NRF2 increased cell apoptosis, decreased cell proliferation, migration and invasion, which significantly decreased malignant phenotypes of Siha cells. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

CO and O₂ Binding to Pseudo-tetradentate Ligand−Copper(I) Complexes with a Variable N-Donor Moiety: Kinetic/Thermodynamic Investigation Reveals Ligand-Induced Changes in... by Heather R. Lucas (2258476)

“…The change in mechanism was not simply related to alterations in ^DLCu^II/I geometries or the order in which O₂ and THF coordinate. …”

Effects of chlorpyrifos on the crustacean <i>Litopenaeus vannamei</i> by Edisson Duarte-Restrepo (8703723)

“…In addition, inhibition of acetylcholinesterase (AChE) was determined in the brain. LC₅₀ (96-hours) was 2.10 μg/L of chlorpyrifos. …”

Reversal of GABAergic postsynaptic currents by the ANO2 inhibitor. by Weiping Zhang (311523)

“…<b>(C)</b> During the continued presence of the ANO2 inhibitor, virtually all postsynaptic currents reverse to positive polarity (Cl^- influx) indicating that GABAergic synapses experience an E_Cl more negative than V_hold. …”

Determination of substrate binding affinity of PKM2 variants. by Suparno Nandi (7285886)

“…(D-F) PEP binding affinities of (D) PKM2 R106A (E) PKM2 N70D (F) PKM2 N75L in the absence and presence of the AAs (color scheme for the AAs is identical to (C)). …”

The influence of fluoxetine treatment on <i>P</i>. <i>berghei</i> pathogenesis. by Li Gao (131516)

H₂S protected human pulmonary artery endothelial cells (HPAECs) from O₂-induced toxicity. by Arul Vadivel (424484)

“…(<b>E</b>) After 48 hours culture in hyperoxia (95%), ROS activity evaluated by measuring the dichlorofluorescein (DCF) shows that hyperoxia increases the ROS production in HPAECs, treatment with GYY4137 significantly decreased the ROS (n = 6/group, *P<0.005 Hyperoxia vs O₂+H₂S).…”

Potassium Zinc Borohydrides Containing Triangular [Zn(BH₄)₃]⁻ and Tetrahedral [Zn(BH₄)_<i>x</i>Cl_4–<i>x</i>]<sup>2–... by Radovan Černý (1441396)

“…Tetragonal K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> is a substitutional and deformation variant of the tetragonal (<i>I</i>4/<i>mcm</i>) Cs₃CoCl₅ structure type possibly with the space group <i>P</i>4₂/<i>ncm</i>. K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> decomposes nearly at the same temperature as KZn(BH₄)₃, i.e., at ∼400 K, with the formation of K₂Zn(BH₄)_<i>x</i>Cl_4–<i>x</i> and KBH₄, indicating that the compound is an adduct of the two latter compounds.…”

Potassium Zinc Borohydrides Containing Triangular [Zn(BH₄)₃]⁻ and Tetrahedral [Zn(BH₄)_<i>x</i>Cl_4–<i>x</i>]<sup>2–... by Radovan Černý (1441396)

“…Tetragonal K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> is a substitutional and deformation variant of the tetragonal (<i>I</i>4/<i>mcm</i>) Cs₃CoCl₅ structure type possibly with the space group <i>P</i>4₂/<i>ncm</i>. K₃Zn(BH₄)_<i>x</i>Cl_5–<i>x</i> decomposes nearly at the same temperature as KZn(BH₄)₃, i.e., at ∼400 K, with the formation of K₂Zn(BH₄)_<i>x</i>Cl_4–<i>x</i> and KBH₄, indicating that the compound is an adduct of the two latter compounds.…”

G6 Reduces the Levels of Vimentin Protein within T98G-derived Tumors. by Rebekah Baskin (622078)

“…Scale bars represent either 50 µm (top panels) or 10 µm (bottom panels). D) The intensity of vimentin staining was quantified via relative pixel counting and the average pixel counts were then plotted as a function treatment group. …”

LBH589 treatment inhibited the growth of SK-NEP-1 xenograft tumors in nude mice. by Tao Yan-Fang (770096)

“…Down regulation of Bcl-2 and cleaved PARP and caspase 9 was observed after 24 hours of treatment with 50nM and 100nM LBH589. …”

Optimal endobronchial tool sizes for targeting lung lesions based on 3D modeling by Torre M. Bydlon (295015)

“…The simulations showed that the percentage of reachable lesions decreases with increasing tool diameter and decreasing lesion diameter. …”

Electrochemical Synthesis and Structural and Physical Characterization of One- and Two-Electron-Reduced Forms of [SMo₁₂O₄₀]^2- by Truc Vu (2942610)

“…Under these conditions, [SMo₁₂O₄₀]^3- protonates and disproportionates into [SMo₁₂O₄₀]^2- and the (2e^-, 2H⁺)-reduced anion [H₂SMo₁₂O₄₀]^2-.…”

Responses to paraquat-induced oxidative stress in transgene flies. by Jeannette A. E. Söderberg (221671)

“…Knockdown of <i>Dilp5</i> leads to a drastic increase in median and total lifespan (P<0.001 and P<0.0005 compared to parental controls; n = 50–60 for the different genotypes) whereas <i>Sod2</i>-RNAi decreases lifespan (P<0.01 and P<0.02 compared to parental controls; n = 50–60 for the different genotypes).…”

SYT-SSX2 associates with Polycomb complex proteins. by Roy Barco (265844)

BRF2 activation contributes to cell growth and proliferation. by William W. Lockwood (163274)

“…(B) Decrease in <i>BRF2</i> mRNA levels in H520 cells expressing shRNAs targeting <i>BRF2</i> relative to those expressing a negative vector control (mean ± SEM of triplicate samples). …”

Image2_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.TIF by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.…”