LBH589 treatment inhibited the growth of SK-NEP-1 xenograft tumors in nude mice. by Tao Yan-Fang (770096)

“…Down regulation of Bcl-2 and cleaved PARP and caspase 9 was observed after 24 hours of treatment with 50nM and 100nM LBH589. …”

Optimal endobronchial tool sizes for targeting lung lesions based on 3D modeling by Torre M. Bydlon (295015)

“…The simulations showed that the percentage of reachable lesions decreases with increasing tool diameter and decreasing lesion diameter. …”

Electrochemical Synthesis and Structural and Physical Characterization of One- and Two-Electron-Reduced Forms of [SMo₁₂O₄₀]^2- by Truc Vu (2942610)

“…Under these conditions, [SMo₁₂O₄₀]^3- protonates and disproportionates into [SMo₁₂O₄₀]^2- and the (2e^-, 2H⁺)-reduced anion [H₂SMo₁₂O₄₀]^2-.…”

Responses to paraquat-induced oxidative stress in transgene flies. by Jeannette A. E. Söderberg (221671)

“…Knockdown of <i>Dilp5</i> leads to a drastic increase in median and total lifespan (P<0.001 and P<0.0005 compared to parental controls; n = 50–60 for the different genotypes) whereas <i>Sod2</i>-RNAi decreases lifespan (P<0.01 and P<0.02 compared to parental controls; n = 50–60 for the different genotypes).…”

SYT-SSX2 associates with Polycomb complex proteins. by Roy Barco (265844)

BRF2 activation contributes to cell growth and proliferation. by William W. Lockwood (163274)

“…(B) Decrease in <i>BRF2</i> mRNA levels in H520 cells expressing shRNAs targeting <i>BRF2</i> relative to those expressing a negative vector control (mean ± SEM of triplicate samples). …”

Image2_Anti-hyperglycemic effects of Cissus quadrangularis extract via regulation of gluconeogenesis in type 2 diabetic db/db mice.TIF by Jeong-Won Kim (18464976)

“…In this study, the therapeutic effects of C. quadrangularis extract (CQR-300) on type 2 diabetes mellitus (T2DM) were investigated in a leptin receptor-mutated db/db mouse model.…”

The influence of 5-HT in mice serum on <i>Plasmodium</i> infection in mosquitoes. by Li Gao (131516)

Two electrophysiological sleep states exist in the Argentine tegu. by Paul-Antoine Libourel (561599)

“…(I) Histograms showing from top to bottom a significant decrease of the heart rate variability (<i>p</i> = 0.0079, <i>n</i> = 5); an increase in the number of eye movements (<i>p</i> = 0.0079, <i>n</i> = 5); and a small decrease in muscle tone computed as the norm of the Hilbert transform (<i>p</i> = 0.0079, <i>n</i> = 5) between S2 (red) and S1 (bluish) for each episode lasting more than two seconds. …”

Model outlining the histone chaperone-mediated nucleosome assembly process illustrated in free-energy reaction diagram. by Hsiu-Fang Fan (214382)

5-HT supplementation induces mitochondrial damage. by Li Gao (131516)

DataSheet1_Macleayins A From Macleaya Promotes Cell Apoptosis Through Wnt/β-Catenin Signaling Pathway and Inhibits Proliferation, Migration, and Invasion in Cervical Cancer HeLa Ce... by Chunmei Sai (11240097)

“…We found that MA inhibited the growth of HeLa cells at 72 h (IC₅₀ = 26.88 µM) via inducing apoptotic process, reduced the proliferation rate by 29.89%, and decreased the cells migration and invasion as compared to the untreated group. …”

The cochlear nuclear complex is differently affected in <i>Hoxb1</i>, <i>Hoxb2</i>, and <i>Hoxa2</i> mutants. by Maria Di Bonito (280277)

“…(D) Formation of the AVCN is strongly affected in E18.5 <i>Hoxa2^null</i> brains, as seen by decreased expression of <i>Atoh7</i> and <i>Hoxb2</i> (arrows). …”

Increased Myeloid Progenitors in Twist-2–Deficient Mice by Andrew B Sharabi (269342)

“…</p> <p>(C) Flow cytometric analysis showing a subtle decrease in Lin⁻c-Kit⁺Sca1⁺ HSC compartment in Twist-2 KO mice. …”

Image_1_SUMOylation of the Kv4.2 Ternary Complex Increases Surface Expression and Current Amplitude by Reducing Internalization in HEK 293 Cells.pdf by Meghyn A. Welch (11633842)

“…Second, instead of decreasing IA Gmax, enhanced SUMOylation at K579 now produced a significant ∼37–70% increase in IA maximum conductance (Gmax) and a significant ∼30–50% increase in Kv4.2g surface expression that was accompanied by a 65% reduction in TC internalization. …”

Graph of R2score value results. by Qirong Lu (5155976)

Unlike SIRPγ^high T-cells, sub-optimal numbers of SIRPγ^low T-cells are sufficient to cause xenoGVHD in NSG mice. by Sushmita Sinha (348580)

Activity of miR-124 and miR-23a in NSC-derived neurons and astrocytes. by Annalisa Lattanzi (427545)

“…(B–E) A significant decrease of GFP expression is observed in bdLV.miRT124-transduced neurons (βtubIII, MAP2) (<b>B, C</b>) and in bdLV.miRT23a-transduced astrocytes (GFAP) and immature glial cells (nestin) (<b>D, E</b>). …”

Fucose treatment inhibits invadopodia formation and ECM degradation. by Tyler Keeley (5429525)

Population effects are also evident in single subjects. by Philipp Schwedhelm (3558275)

“…For each subject, two Naka-Rushton equations per cue type were fit to the psychophysical data, revealing four informative coefficients. A decrease in <i>c</i>₅₀ between validly and invalidly cued trials indicates a contrast gain effect and an increase in <i>d</i>′_<i>max</i> a response gain effect. …”