IL-2 activates the podocyte mitochondrial intrinsic pathway and inhibits podocyte autophagy. by Arnold H. Zea (411800)

Effect of SARS-CoV-2 3CL^pro on 2N4R tau degradation. by Raphael Josef Eberle (16859186)

“…<b>E</b>: Chromatogram of peak region III shown enlarged, two protein bands appear over the 72h experimental time.…”

TRLS2^-/- mice demonstrate appropriate hormone responses to low blood glucose. by Daniel W. Fisher (4872406)

“…<p><b>A)</b> Blood glucose was assessed at two time points in <i>Trls2</i>^+/+, <i>Trls2</i>^+/-, and <i>Trls2</i>^-/- mice, one hour after lights on (top graph) and an hour after lights off (bottom graph). …”

Effect of fluspirilene treatment on the expressions of important proteins involved in G1-to-S transition. by Xi-Nan Shi (765399)

“…<p>Fluspirilene treatment decreased the expressions of CDK2, Rb, cyclin E, pho-CDK2 and pho-Rb, but not cyclin D1 and cyclin B1.…”

LRP1 interacts with GluA1 and regulates its turnover in neurons. by Ming Gan (673850)

Image2_Case report: Double filtration plasmapheresis (DFPP) for severe rhesus-D alloimmunization in two pregnant patients.tiff by Yuling Liang (4636447)

“…The titers of IgG-D, IgG-A, and IgG-B decreased after DFPP treatment. One woman successfully prolonged pregnancy until 20 weeks of gestation. …”

Image_2_The Pioneer Transcription Factor Foxa2 Modulates T Helper Differentiation to Reduce Mouse Allergic Airway Disease.jpeg by Diana C. Yánez (11418371)

“…Conditional deletion of Foxa2 from T-cells led to increased Th2 cytokine secretion and differentiation, but decreased Th1 differentiation and IFN-γ expression in vitro. …”

image_2_Resolvin D2 Restrains Th1 Immunity and Prevents Alveolar Bone Loss in Murine Periodontitis.jpeg by Gabriel Mizraji (5139530)

Impaired muscle function and integrity in SGCA- and SGCD-null mice. by S. Pasteuning-Vuhman (4348486)

“…<b>(d)</b> Creatine kinase levels were significantly elevated in both LGMD strains. <b>(e)</b> No significant differences were detected in respiration amplitude between the mouse models. …”

The variation of gravity scaling exponent of COVID-19 diffusion in Hubei Province. by Yanguang Chen (204520)

Image_1_The novel chimeric multi-agonist peptide (GEP44) reduces energy intake and body weight in male and female diet-induced obese mice in a glucagon-like peptide-1 receptor-depe... by James E. Blevins (11405813)

“…We hypothesized that GEP44 reduces energy intake and BW primarily through a GLP-1R dependent mechanism. To test this hypothesis, GLP-1R^+/+ mice and GLP-1R null (GLP-1R^-/-) mice were fed a high fat diet for 4 months to elicit diet-induced obesity prior to undergoing a sequential 3-day vehicle period, 3-day drug treatment (5, 10, 20 or 50 nmol/kg; GEP44 vs the selective GLP-1R agonist, exendin-4) and a 3-day washout. …”

Figure 1; Figure 2; Figure 3; Figure 4; Figure 5; Table 1; Table 2; Table 3; Table 4; SupTable 1; SupTable 2; SupTable 3 by Ramachandran Chelliah (3837415)

“…Smoking also disrupts calciotropic hormone activity (e.g., reduced levels of 25-OH-D and 1,25-(OH)₂-D), leading to decreased intestinal calcium absorption and heightened bone resorption via the RANKL/OPG axis. …”

Association between scPDSI and dengue incidence in 291 locations across the eight countries, relative to a scPDSI value of zero. by Sophearen Ith (13194956)

<i>Ezh2^fl/fl:Nkx2.5-cre+</i> mice exhibited hypoplastic endocardial cushions. by Li Chen (5749)

“…<p>(<b>A–B′</b>) H&E staining revealed a decrease in the cell population in the EC region of <i>Ezh2</i> null hearts compared with that of control (arrows) at E10.5. …”

Mechanism of GD2-induced platelet apoptosis. by Kim Anh Nguyen (416639)

“…NS: Not significant. (<b>E</b>) Western blot demonstrates strong expression of Bax and Bak in GD2-treated human platelets and this expression was prevented by blocking anti Siglec-7 pAb. …”

Image1_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

Image2_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

Image4_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

Image3_Biochanin A Regulates Key Steps of Inflammation Resolution in a Model of Antigen-Induced Arthritis via GPR30/PKA-Dependent Mechanism.TIF by Franciel Batista Felix (10699536)

LS174T and HepG2 cells predominantly express sLe^X on core 2 O-glycans. by Catherine A. St. Hill (357388)

“…(E) Similar results were observed for HepG2 cells after BGN, ^#p = 0.0005, and after BGN and SWN, ^##p<0.0001, compared to untreated cells.…”