Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

Subjects:

Development of (2-(Benzyloxy)phenyl)methanamine Derivatives as Potent and Selective Inhibitors of CARM1 for the Treatment of Melanoma by Zhihao Liu (419349)

Subjects:

Density increases cadherin-11 and GSK3β inhibitors decrease cadherin-11 expression. by Anne K. Farina (266373)

Imatinib induces the differentiation of human normal erythroblasts and decreases cell surface expression of c-Kit. by Diane D'allard (405441)

Luteolin decreases production of IL-6, IL-8 and VEGF in TNF-triggered primary NHEKs. by Zuyi Weng (109988)

Tyro 3 overexpression decreases the production of Aβ from 293APPswe cells and Gas6 inhibits the effect in a concentration-dependent manner. by Yan Zheng (61178)

“…Both sets of cells were treated with different concentrations of Gas6 (12.5, 25, 50, 100 ng/ml). Total Aβ was also significantly lower in Tyro-3-transfected cells treated with low concentrations of Gas6 (12.5, 25 ng/ml) than in GFP controls. …”

<i>Pw1</i> deletion does not result in significant decrease in oxytocin production and release. by Anne-Lyse Denizot (3170142)

Apoptosis is induced in EYFP-LIPT2 and ΔmitotagLIPT2 expressing cells. by Emanuele Bernardinelli (4117372)

Decrease of excitability in small IB4-positive TG neurons over-expressing TRESK channels. by Zhaohua Guo (383295)

Leishmanization with <i>L</i>. <i>major</i> + Pam3CSK4 decreases lesion size and parasite burden in mice. by Lu Huang (211625)

Methylation levels of the <i>Ucp1</i> promoter decreased following genistein (GEN) treatment. by Noriko Sato (201880)

<i>Pf-Rel</i> knockdown decreased the <i>Nacrein</i> gene expression level. by Juan Sun (439334)

“…The expression levels of <i>Nacrein</i> slightly decreased after dsRNA injection, compared to the control group. 6 days after injection, the expression level of both <i>Pf-Rel</i> and <i>Nacrein</i> were suppressed by nearly 50%. …”

Effects of TGF-β1 on the expression of fibrosis indicators in HBdSMCs and the effects of MEL on the expression of fibrosis indicators in HBdSMCs induced by TGF-β1. by Yang Zhang (30734)

Sustained expression of radmis results in decreased cell proliferation and increased cell-cycle exit of NSPCs. by Takahito Yumoto (481671)

The density of the Som+ cells in the EPL of the OB is significantly decreased in the Sp8 conditional mutant mice. by Xuhua Jiang (436379)

<i>mitfa</i> and <i>mitfb</i> expression is decreased in <i>otx</i> morphants. by Brandon M. Lane (123574)

“…<p>Expression of <i>mitfa</i> (A–D) and <i>mitfb</i> (E–H) was examined through in situ hybridization at the 21 somite stage in embryos injected with a control morpholino (A,E), or morpholinos against <i>otx1a</i> (B,F), <i>otx1b</i> (C,G), or <i>otx2</i> (D,H). …”

Antagonism of miR-21 reversed EMT phenotype, as well as decreased cell migration and invasion. by Mingli Han (318317)

“…<p>MDA-MB-231 cells were transfected with hsa-miR-21 antagomir or hsa-miR-21 antagomir control at a final concentration of 50 nmol for 48 h. (A) MDA-MB-231 cells were treated with hsa-miR-21 antagomir decreased the expression of miR-21, as compared to control groups (n1 = n2 = 3; p = 0.0015), by real-time RT-PCR analysis. …”

Migratory CD103+ DC in the MLN show decreased expression of CD86 and CD40. by Matheswaran Kandasamy (105167)

Protection of ethanol-mediated neuronal cell death by the AGE inhibitor pyridoxamine by decreasing RAGE levels. by Kyunghee Byun (162379)

Gene ontology biological processes overrepresented among genes exhibiting decreased expression in human psoriasis. by William R. Swindell (175427)

“…<p>A total of 3540 transcripts were identified as significantly decreased in psoriatic plaques obtained from human patients relative to normal skin obtained from control subjects (FDR-adjusted P<0.05 and log₂-transformed fold-change less than -0.50). …”