DataSheet_1_PRMT5 Promotes Cyclin E1 and Cell Cycle Progression in CD4 Th1 Cells and Correlates With EAE Severity.docx by Stephanie A. Amici (10939380)

“…Treatment of T helper 1 (mTh1) cells with the selective PRMT5 inhibitor, HLCL65, arrested activation-induced T cell proliferation at the G1 stage of the cell cycle, suggesting PRMT5 promotes cell cycle progression in CD4⁺ T cells. The Cyclin E1/Cdk2 pair promoting G1/S progression was also decreased after PRMT5 inhibition, as was the phosphorylation of retinoblastoma. …”

Mass spectrum of 7-MH. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

ANOVA for 7-MH yield. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

Raw images of Western blot experiment. by Juthamart Maneenet (15999769)

“…This study evaluated the anti-cancer potential of 7-methoxyheptaphylline (7-MH), a carbazole alkaloid from <i><i>Clausena harmandiana</i></i>, against pancreatic cancer cells (PANC-1) and developed an environmentally sustainable extraction methodology using ultrasonic-assisted extraction (UAE). 7-MH demonstrated selective cytotoxicity against PANC-1 cells with preferential activity under nutrient deprivation conditions (PC₅₀ = 4.54 μM) compared to nutrient-rich conditions (IC₅₀ = 46.84 μM). …”

Fig 1 - by Emily Baker (3492485)

Experimental setup of H9c2 cells exposed to normoxia/hypoxia. by Frederik Abel (8452101)

Association of knee OA AMVF patients with continuous variables. by Izzatul Nadiah Zolkiply (19681460)

S1 Graphical abstract - by Jennifer Astley (19859612)

“…</p><p>Results</p><p>Population structure did not appear to affect the timeline of elimination targets and screening individuals over the age of 30 at a high (50% per year) coverage could bring forward achievement of the incidence elimination target by four years compared to baseline (approximately 6% per year). …”

Data_Sheet_2_Nitrate Feed Improves Growth and Ethanol Production of Clostridium ljungdahlii With CO2 and H2, but Results in Stochastic Inhibition Events.pdf by Christian-Marco Klask (8802542)

“…; and (2) does feeding nitrate influence the product spectrum under controlled pH conditions with CO₂ and H₂? …”

Strong Effects of Temperature on the Early Life Stages of a Cold Stenothermal Fish Species, Brown Trout (<i>Salmo trutta </i>L.) by Emilie Réalis-Doyelle (3170874)

“…The energetic budget showed that at the two extreme temperatures (4°C and 12°C) there was less energy left in the yolk sac at first food intake, suggesting a limited ability to survive starvation.…”

Estimation of influenza transmission and death rates among individuals aged 0–17, 18–64, and 65+ in the United States using actual data. by Shuanglin Jing (11886368)

Protocol (timeline) of this study. by Akira Umeda (14197382)

SURF6 overexpression does not disturb morphology of HeLa cells [31]. by Anastasiia Moraleva (16548419)

IQGAP1 alters the expression of YAP. by Shaojun Huang (12489901)

SURF6 knockdown does not disturb morphology of HeLa cells. by Anastasiia Moraleva (16548419)

Human <i>CTSZ</i> variants are associated with TB severity, and CTSZ is present at the host-pathogen interface within human pulmonary <i>Mtb</i> granulomas. by Rachel K. Meade (22216529)

Phosphatidylglycerol molecular species composition during microspore embryogenesis of <i>Brassica napus</i>. by Xin-Qiao Du (13150022)

Phosphatidylcholine molecular species composition during microspore embryogenesis of <i>Brassica napus</i>. by Xin-Qiao Du (13150022)

S1 Data - Cathepsin Z is a conserved susceptibility factor underlying tuberculosis severity by Rachel K. Meade (22216529)

Phosphatidylethanolamine molecular species composition during microspore embryogenesis of <i>Brassica napus</i>. by Xin-Qiao Du (13150022)